Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China

Autor: Yan, Ma, Dong Shan, Zhu, Ren Bo, Chen, Nan Nan, Shi, Si Hong, Liu, Yi Pin, Fan, Gui Hui, Wu, Pu Ye, Yang, Jiang Feng, Bai, Hong, Chen, Li Ying, Chen, Qiao, Feng, Tuan Mao, Guo, Yong, Hou, Gui Fen, Hu, Xiao Mei, Hu, Yun Hong, Hu, Jin, Huang, Qiu Hua, Huang, Shao Zhen, Huang, Liang, Ji, Hai Hao, Jin, Xiao, Lei, Chun Yan, Li, Min Qing, Li, Qun Tang, Li, Xian Yong, Li, Hong De, Liu, Jin Ping, Liu, Zhang, Liu, Yu Ting, Ma, Ya, Mao, Liu Fen, Mo, Hui, Na, Jing Wei, Wang, Fang Li, Song, Sheng, Sun, Dong Ting, Wang, Ming Xuan, Wang, Xiao Yan, Wang, Yin Zhen, Wang, Yu Dong, Wang, Wei, Wu, Lan Ping, Wu, Yan Hua, Xiao, Hai Jun, Xie, Hong Ming, Xu, Shou Fang, Xu, Rui Xia, Xue, Chun, Yang, Kai Jun, Yang, Sheng Li, Yuan, Gong Qi, Zhang, Jin Bo, Zhang, Lin Song, Zhang, Shu Sen, Zhao, Wan Ying, Zhao, Kai, Zheng, Ying Chun, Zhou, Jun Teng, Zhu, Tian Qing, Zhu, Hua Min, Zhang, Yan Ping, Wang, Yong Yan, Wang

Publikováno v: Biomedical and Environmental Sciences

Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear. Me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6bf89eb949881ab5b37c27a7b6e812e6
http://europepmc.org/articles/PMC7817475

Increased Th17 activation and gut microbiota diversity are associated with pembrolizumab-triggered tuberculosis

Autor: Yin-Zhen Wang, Ji-Xue Zhou, Bing Fang, Zhi-Dong Hu, Ka-Wing Wong, Fan Xia, Shi-Jia Liu, Yun-Bin Zhang

Publikováno v: Cancer immunology, immunotherapy : CII. 69(12)

A hypersensitivity response akin to immune reconstitution inflammatory syndrome (IRIS) has been proposed as a mechanism responsible for anti-PD-1 therapy-induced tuberculosis. IRIS is associated with enhanced activation of IL-17A-expressing CD4 + T c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607b03edefe58ccca1a594377225707b
https://pubmed.ncbi.nlm.nih.gov/32761425

On-line immobilized trypsin microreactor for evaluating inhibitory activity of phenolic acids by capillary electrophoresis and molecular docking

Autor: Hao Zhang, Zhao-Yu Wu, Yin-Zhen Wang, Feng-Qing Yang, De-qiang Li, Dong-Dong Zhou

Publikováno v: Food Chemistry. 310:125823

Phenolic acids, which are important aromatic secondary metabolites, are widely distributed in plant foods. In this study, a simple, economical and fast on-line immobilized trypsin microreactor was developed for evaluating the inhibitory activity of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8731d174b701338f0dbf7663624bd69d
https://doi.org/10.1016/j.foodchem.2019.125823

Evaluation of thrombin inhibitory activity of catechins by online capillary electrophoresis-based immobilized enzyme microreactor and molecular docking

Autor: Zhao-Yu Wu, Hua Chen, Feng-Qing Yang, Zhining Xia, Qiao-Qiao Li, Yin-Zhen Wang

Publikováno v: Talanta. 185

An online capillary electrophoresis (CE)-based thrombin (THR) immobilized enzyme microreactor (IMER) method was established to screen THR inhibitors in this study. S-2366 was used as chromogenic substrate for determination of THR activity and other k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c341d93e8a813cd6ac30778687bf03
https://pubmed.ncbi.nlm.nih.gov/29759183

Evaluation of interactions between RAW264.7 macrophages and small molecules by capillary electrophoresis

Autor: Yin-Zhen Wang, Yuanjia Hu, Feng-Qin Wang, Qiao-Qiao Li, Zhining Xia, Jian-Bo Wan, Peng Li, Feng-Qing Yang, Qian Zhang

Publikováno v: Electrophoresis. 38(6)

In this study, the affinity interactions between RAW 264.7 macrophages and three small molecules include naringin, oleuropein and paeoniflorin were evaluated by affinity capillary electrophoresis (ACE), partial filling affinity capillary electrophore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11b17c668857e1e402f31eb1900bdf6
https://pubmed.ncbi.nlm.nih.gov/27935131