Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yin-Sui Xu"'
Publikováno v:
New Journal of Chemistry. 45:20743-20750
It is imperative to develop innovative and efficient antibacterial agents, on account of the mounting prevalence of complicated infections induced by multidrug-resistant bacteria. In this work, Chol-b-Lys nanoparticles (CL-NPs) with a diameter of 304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b63fbbfddddfc5730853f6e623adc18f
https://doi.org/10.1039/d1nj03944j
https://doi.org/10.1039/d1nj03944j
Autor:
Yin-Sui Xu, Jia-Zhu Chigan, Jia-Qi Li, Huan-Huan Ding, Le-Yun Sun, Lu Liu, Zhenxin Hu, Ke-Wu Yang
Publikováno v:
Bioorganic chemistry. 124
The emerging COVID-19 pandemic generated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has severely threatened human health. The main protease (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198ca12c3a0f18c0762f36f26685fe69
https://pubmed.ncbi.nlm.nih.gov/35462235
https://pubmed.ncbi.nlm.nih.gov/35462235
Publikováno v:
Chemical biologydrug designREFERENCES. 99(2)
Bacterial resistance caused by metallo-β-lactamases (MβLs) has become an emerging public health threat, and the development of MβLs inhibitor is an effective way to overcome the resistance. In this study, thirteen novel O-aryloxycarbonyl hydroxama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00958dc4cfb27d4eabf7444af1af0fe
https://pubmed.ncbi.nlm.nih.gov/34862744
https://pubmed.ncbi.nlm.nih.gov/34862744
Autor:
Lu, Liu, Yin-Sui, Xu, Jia-Zhu, Chigan, Le, Zhai, Huan-Huan, Ding, Xiao-Rong, Wu, Wei-Ya, Chen, Ke-Wu, Yang
Publikováno v:
Bioorganic Chemistry. 127:105928
The superbug infection mediated by metallo-β-lactamases (MβLs) has grown into anemergent health threat, and development of MβL inhibitors is an ideal strategy to combat the infection. In this work, twenty-five thiosemicarbazones 1a-e, 2a-e, 3a-e,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e2c77e49274bd03668db5d9a1fed77
https://doi.org/10.1016/j.bioorg.2022.105928
https://doi.org/10.1016/j.bioorg.2022.105928
Autor:
Ke-Wu Yang, Han Gao, Yin-Sui Xu, Jia-Qi Li, Le Zhai, Huan Wang, Lu Liu, Jia-Zhu Chigan, Peng-Wei Kang
Publikováno v:
Bioorganic chemistry. 114
The expression of β-lactamases, especially metallo-β-lactamases (MβLs) in bacteria is one of the main causes of drug resistance. In this work, an effective N-acylhydrazone scaffold as MβL inhibitor was constructed and characterized. The biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c710c442cf1cbc5e741cb6d2e93794
https://pubmed.ncbi.nlm.nih.gov/34229201
https://pubmed.ncbi.nlm.nih.gov/34229201
Publikováno v:
Bioorganic Chemistry. 120:105654
The "superbug" infection caused by metallo-β-lactamases (MβLs) has grown into anemergent health threat, and development of effective MβL inhibitors to restore existing antibiotic efficacy is an ideal alternative. Although the serine-β-lactamase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01919ed911505a28afd87909f8636971
https://doi.org/10.1016/j.bioorg.2022.105654
https://doi.org/10.1016/j.bioorg.2022.105654