Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Yin-Shan Ng"'
Autor:
Zhengping Hu, Issahy Cano, Kahira L. Saez-Torres, Michelle E. LeBlanc, Magali Saint-Geniez, Yin-Shan Ng, Pablo Argüeso, Patricia A. D’Amore
Publikováno v:
Cells, Vol 9, Iss 6, p 1413 (2020)
Endomucin (EMCN) is the type I transmembrane glycoprotein, mucin-like component of the endothelial cell glycocalyx. We have previously shown that EMCN is necessary for vascular endothelial growth factor (VEGF)-induced VEGF receptor 2 (VEGFR2) interna
Externí odkaz:
https://doaj.org/article/32527e0a5dd34f8e9aae83b4878b641f
Autor:
Cindy Park-Windhol, Yin Shan Ng, Jinling Yang, Vincent Primo, Magali Saint-Geniez, Patricia A. D’Amore
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/94659447fca44762934706f78bb20464
Autor:
Patricia A. D'Amore, Yin-Shan Ng, Magali Saint-Geniez, Michelle E. LeBlanc, Kahira L. Saez-Torres, Issahy Cano, Jinling Yang
Publikováno v:
J Biol Chem
Contact between inflammatory cells and endothelial cells (ECs) is a crucial step in vascular inflammation. Recently, we demonstrated that the cell-surface level of endomucin (EMCN), a heavily O-glycosylated single-transmembrane sialomucin, interferes
Autor:
Yin-Shan Ng, Patricia A. D'Amore, Cindy Park-Windhol, Jinling Yang, Vincent Primo, Magali Saint-Geniez
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Angiogenesis is central to both normal and pathologic processes. Endothelial cells (ECs) express O-glycoproteins that are believed to play important roles in vascular development and stability. Endomucin-1 (EMCN) is a type I O-glycosylated, sialic-ri
Autor:
Lili Feng, Yin Shan Ng, Peter Adamson, Kameran Lashkari, Kei Ying Vivian Lee, Mariasilvia Evangelista, David T. Shima, Meihua Ju, Daiju Iwata, Richard Foxton, Ashley Mackey
Publikováno v:
The American Journal of Pathology. 187:2208-2221
Current treatments for choroidal neovascularization, a major cause of blindness for patients with age-related macular degeneration, treat symptoms but not the underlying causes of the disease. Inflammation has been strongly implicated in the pathogen
Autor:
Yin-Shan Ng, Zhengping Hu, Patricia A. D'Amore, Michelle E. LeBlanc, Kahira L. Saez-Torres, Magali Saint-Geniez, Issahy Cano, Pablo Argüeso
Publikováno v:
Cells
Cells, Vol 9, Iss 1413, p 1413 (2020)
Volume 9
Issue 6
Cells, Vol 9, Iss 1413, p 1413 (2020)
Volume 9
Issue 6
Endomucin (EMCN) is the type I transmembrane glycoprotein, mucin-like component of the endothelial cell glycocalyx. We have previously shown that EMCN is necessary for vascular endothelial growth factor (VEGF)-induced VEGF receptor 2 (VEGFR2) interna
Autor:
Esaie Pierre, Scott J Robbie, Peter Adamson, Achim Hans-Peter Krauss, Meihua Ju, Kanako Izumi-Nagai, David T. Shima, David C. Gale, Yin-Shan Ng, James W B Bainbridge, Nori Nagai
Publikováno v:
The American Journal of Pathology. 185:2534-2549
Choroidal neovascularization (CNV) is a defining feature of wet age-related macular degeneration. We examined the functional role of CCR3 in the development of CNV in mice and primates. CCR3 was associated with spontaneous CNV lesions in the newly de
Autor:
Richard Foxton, Peng T. Khaw, Yin-Shan Ng, James Edwards Morgan, Sauparnika Vijay, Annegret Dahlmann-Noor, David T. Shima, Arthur Finkelstein
Publikováno v:
The American Journal of Pathology
Vascular endothelial growth factor A (VEGF-A) is a validated therapeutic target in several angiogenic- and vascular permeability–related pathological conditions, including certain cancers and potentially blinding diseases, such as age-related macul
Autor:
Nobuo Jo, David T. Shima, Lichun Zhong, Jo Akita, Kazuaki Nishijima, Gregory S. Robinson, Anthony P. Adamis, John S. Bradley, Yin-Shan Ng, William Schubert, Steven J. Samuelsson
Publikováno v:
The American Journal of Pathology. 171:53-67
Vascular endothelial growth factor-A (VEGF-A) has recently been recognized as an important neuroprotectant in the central nervous system. Given its position as an anti-angiogenic target in the treatment of human diseases, understanding the extent of
Autor:
Cindy Park-Windhol, Jinling Yang, Vincent Primo, Patricia A. D'Amore, Magali Saint-Geniez, Yin-Shan Ng
Publikováno v:
The FASEB Journal. 29
Angiogenesis is central to both normal and pathologic processes. Endothelial cells (ECs) express high levels of O-glycoproteins that are believed to play important roles in vascular development and...