Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement

Autor: Ting Yu, Yanli Li, Fengmei Fan, Hongbao Cao, Xingguang Luo, Shuping Tan, Fude Yang, Xiangyang Zhang, Yin Yao Shugart, L. Elliot Hong, Chiang-Shan R. Li, Yunlong Tan

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)

Abstract Tardive dyskinesia (TD) is a devastating motor disorder associated with the etiological process of schizophrenia or antipsychotic medication treatments. To examine whether cerebral morphological changes may manifest in TD, we used voxel-base

Externí odkaz: https://doaj.org/article/9a7822d2ac9e4183a003d6464cc9eff6

Robust Reference Powered Association Test of Genome-Wide Association Studies

Autor: Yi Wang, Yi Li, Meng Hao, Xiaoyu Liu, Menghan Zhang, Jiucun Wang, Momiao Xiong, Yin Yao Shugart, Li Jin

Publikováno v: Frontiers in Genetics, Vol 10 (2019)

Genome-wide association studies (GWASs) have identified abundant genetic susceptibility loci, GWAS of small sample size are far less from meeting the previous expectations due to low statistical power and false positive results. Effective statistical

Externí odkaz: https://doaj.org/article/fe6c28ad305343a9a6625d62974a9ffc

Supplementary Figures 1-6, Figure Legend 1 from Comprehensive Pathway-Based Association Study of DNA Repair Gene Variants and the Risk of Nasopharyngeal Carcinoma

Autor: Wei-Hua Jia, Yi-Xin Zeng, Timothy J. Jorgensen, Jian Jun Liu, Wei Huang, Li-Zhen Chen, Qi-Sheng Feng, Lina Chen, Qing-Hua Pan, Jin-Xin Bei, Yin Yao Shugart, Hai-De Qin

Supplementary Figures 1-6, Figure Legend 1 from Comprehensive Pathway-Based Association Study of DNA Repair Gene Variants and the Risk of Nasopharyngeal Carcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981e390189922931e5d3466f8b97a9f5
https://doi.org/10.1158/0008-5472.22386096.v1

Mapsnp: an R package to plot a genomic map for single nucleotide polymorphisms.

Autor: Fuquan Zhang, Yong Xu, Hongbao Cao, Chunhui Jin, Zaohuo Cheng, Guoqiang Wang, Yin Yao Shugart

Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0123609 (2015)

Single-nucleotide polymorphism (SNP) is one of the most common sources of genetic variations of the genome. Currently, SNPs are a main target for most genetic association studies. Visualizing genomic coordinates of SNPs, including their physical loca

Externí odkaz: https://doaj.org/article/72ced149f5a04f34bb1d24858d485a3c

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.

Autor: Lea K Davis, Dongmei Yu, Clare L Keenan, Eric R Gamazon, Anuar I Konkashbaev, Eske M Derks, Benjamin M Neale, Jian Yang, S Hong Lee, Patrick Evans, Cathy L Barr, Laura Bellodi, Fortu Benarroch, Gabriel Bedoya Berrio, Oscar J Bienvenu, Michael H Bloch, Rianne M Blom, Ruth D Bruun, Cathy L Budman, Beatriz Camarena, Desmond Campbell, Carolina Cappi, Julio C Cardona Silgado, Danielle C Cath, Maria C Cavallini, Denise A Chavira, Sylvain Chouinard, David V Conti, Edwin H Cook, Vladimir Coric, Bernadette A Cullen, Dieter Deforce, Richard Delorme, Yves Dion, Christopher K Edlund, Karin Egberts, Peter Falkai, Thomas V Fernandez, Patience J Gallagher, Helena Garrido, Daniel Geller, Simon L Girard, Hans J Grabe, Marco A Grados, Benjamin D Greenberg, Varda Gross-Tsur, Stephen Haddad, Gary A Heiman, Sian M J Hemmings, Ana G Hounie, Cornelia Illmann, Joseph Jankovic, Michael A Jenike, James L Kennedy, Robert A King, Barbara Kremeyer, Roger Kurlan, Nuria Lanzagorta, Marion Leboyer, James F Leckman, Leonhard Lennertz, Chunyu Liu, Christine Lochner, Thomas L Lowe, Fabio Macciardi, James T McCracken, Lauren M McGrath, Sandra C Mesa Restrepo, Rainald Moessner, Jubel Morgan, Heike Muller, Dennis L Murphy, Allan L Naarden, William Cornejo Ochoa, Roel A Ophoff, Lisa Osiecki, Andrew J Pakstis, Michele T Pato, Carlos N Pato, John Piacentini, Christopher Pittenger, Yehuda Pollak, Scott L Rauch, Tobias J Renner, Victor I Reus, Margaret A Richter, Mark A Riddle, Mary M Robertson, Roxana Romero, Maria C Rosàrio, David Rosenberg, Guy A Rouleau, Stephan Ruhrmann, Andres Ruiz-Linares, Aline S Sampaio, Jack Samuels, Paul Sandor, Brooke Sheppard, Harvey S Singer, Jan H Smit, Dan J Stein, E Strengman, Jay A Tischfield, Ana V Valencia Duarte, Homero Vallada, Filip Van Nieuwerburgh, Jeremy Veenstra-Vanderweele, Susanne Walitza, Ying Wang, Jens R Wendland, Herman G M Westenberg, Yin Yao Shugart, Euripedes C Miguel, William McMahon, Michael Wagner, Humberto Nicolini, Danielle Posthuma, Gregory L Hanna, Peter Heutink, Damiaan Denys, Paul D Arnold, Ben A Oostra, Gerald Nestadt, Nelson B Freimer, David L Pauls, Naomi R Wray, S Evelyn Stewart, Carol A Mathews, James A Knowles, Nancy J Cox, Jeremiah M Scharf

Publikováno v: PLoS Genetics, Vol 9, Iss 10, p e1003864 (2013)

The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated variants. We have quanti

Externí odkaz: https://doaj.org/article/dcefb124869a49fdb60299acf97e56f6