Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yin Hoon, Chew"'
Autor:
Yin Hoon Chew1,2, Seaton, Daniel D.1,3, Mengin, Virginie4,5, Flis, Anna4, Mugford, Sam T.6, George, Gavin M.7,8, Moulin, Michael9,10, Hume, Alastair11, Zeeman, Samuel C.7, Fitzpatrick, Teresa B.9, Smith, Alison M.6, Stitt, Mark4, Millar, Andrew J.1 Andrew.Millar@ed.ac.uk
Publikováno v:
In Silico Plants. 2022, Vol. 4 Issue 2, p1-15. 15p.
Autor:
Jonathan R. Karr, Yin Hoon Chew
Despite substantial potential to transform bioscience, medicine, and bioengineering, whole-cell models remain elusive. One of the biggest challenges to whole-cell models is assembling the large and diverse array of data needed to model an entire cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec129c64cfef109ad0cd272fa057b7f
http://arxiv.org/abs/2105.10627
http://arxiv.org/abs/2105.10627
Autor:
Balázs Szigeti, John Ap Sekar, Yosef D. Roth, Jonathan R. Karr, Yin Hoon Chew, Arthur P. Goldberg
Publikováno v:
Current Opinion in Biotechnology. 51:97-102
Whole-cell computational models aim to predict cellular phenotypes from genotype by representing the entire genome, the structure and concentration of each molecular species, each molecular interaction, and the extracellular environment. Whole-cell m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3620877419e108600b5c452bb729a397
https://doi.org/10.1016/j.copbio.2017.12.013
https://doi.org/10.1016/j.copbio.2017.12.013
Publikováno v:
SIGSIM-PADS
Whole-cell (WC) models comprehensively predict cellular phenotypes by simulating the biochemistry in individual cells. WC models have the potential to enable bioengineers and physicians to rationally design microorganisms and medical therapies. WC mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6067b7604d4959d43e846c12521aee65
https://doi.org/10.1145/2901378.2901402
https://doi.org/10.1145/2901378.2901402
Publikováno v:
Chew, Y H, Seaton, D & Millar, A 2016, ' Multi-scale modelling to synergise plant systems biology and crop science ', Field crops research, vol. 202 . https://doi.org/10.1016/j.fcr.2016.02.012
At the interface of the plant systems biology and crop modelling communities, a recurring theme is the construction of an in silico plant that links across many levels of biological organisation. These disciplines are not mutually exclusive; each has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef9c975f1c9b80ee0ccaae6238ba555
https://hdl.handle.net/20.500.11820/37328429-fb5e-4c3f-a341-1dabb8e7ded2
https://hdl.handle.net/20.500.11820/37328429-fb5e-4c3f-a341-1dabb8e7ded2
Autor:
Vasundra Touré, Matteo Cantarelli, Argyris Zardilis, Bertrand Moreau, Arthur P. Goldberg, Milenko Tokic, Pınar Pir, Dagmar Waltemath, Kieran Smallbone, Jens Hahn, Kambiz Baghalian, Daewon Lee, Naveen K. Aranganathan, Vijayalakshmi Chelliah, Arne T. Bittig, Namrata Tomar, Anna Zhukova, Florian Wendland, Marcus Krantz, Yan Zhu, Mahesh C. Sharma, Wolfram Liebermeister, Frank Bergmann, Joseph Cursons, Rafael S. Costa, Matthias König, Leandro Watanabe, Pedro Mendes, Natalie J. Stanford, James T. Yurkovich, Falk Schreiber, Harold F. Gómez, J. Kyle Medley, Martin Scharm, Vincent Knight-Schrijver, Denis Kazakiewicz, Ilya Kiselev, Jannis Uhlendorf, Daniel Alejandro Priego-Espinosa, Chris J. Myers, Sucheendra K. Palaniappan, Hojjat Naderi-Meshkin, Michael Hucka, Thawfeek M. Varusai, Nikita Mandrik, Markus Wolfien, Begum Alaybeyoglu, Paulo E. Pinto Burke, Daniel Federico Hernandez Gardiol, Audald Lloret-Villas, Tom Theile, Tuure Hameri, Christian Knüpfer, Jonathan R. Karr, Je-Hoon Song, Yin Hoon Chew, Tobias Czauderna
Publikováno v:
IEEE transactions on bio-medical engineering
Objective: Whole-cell (WC) modeling is a promising tool for biological research, bioengineering, and medicine. However, substantial work remains to create accurate comprehensive models of complex cells. Methods: We organized the 2015 Whole-Cell Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98a6b1a1a6703599a5ab9a1f9682138
Autor:
Yoke Lin Shia, Yin Hoon Chew, Mohamad Roji Sarmidi, Fadzilah Adibah Abdul Majid, Chew Tin Lee, Ramlan Aziz, Lee Suan Chua
Publikováno v:
Molecular and Cellular Endocrinology. 307:57-67
A mathematical model to describe the oscillatory bursting activity of pancreatic beta-cells is combined with a model of glucose regulation system in this work to study the bursting pattern under regulated extracellular glucose stimulation. The bursti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd68ce6438a31c54dbccf6a363fde6b
https://doi.org/10.1016/j.mce.2009.03.005
https://doi.org/10.1016/j.mce.2009.03.005
Publikováno v:
Food and Bioproducts Processing. 86:276-282
The application of immobilized enzyme in packed-bed reactor is gaining interest in the industry as it offers advantages over conventional chemical reactions. However, external mass transfer limitation is significant in immobilized enzyme packed-bed r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::373d620cbd81c6f72c38bbfbd6bd93da
https://doi.org/10.1016/j.fbp.2008.02.001
https://doi.org/10.1016/j.fbp.2008.02.001
Publikováno v:
Applied Thermal Engineering. 28:2089-2099
Process integration techniques have been widely accepted as an effective tool in synthesising a cost optimal heat exchanger network (HEN). However, most works on HEN synthesis have mainly focused on continuous processes. Much less work has been carri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf03a9b104c6a2ff6647e812c6019b47
https://doi.org/10.1016/j.applthermaleng.2008.02.006
https://doi.org/10.1016/j.applthermaleng.2008.02.006
Autor:
Yin Hoon Chew, Chew Tin Lee, Kian Kai Cheng, Ramlan Aziz, Mohamad Roji Sarmidi, Lee Suan Chua
Publikováno v:
Biochemical Engineering Journal. 39:516-520
The application of immobilized lipase (EC 3.1.1.3) is gaining interest in the oleochemical industry as it offers advantages over conventional chemical reactions. In the present study, a commercial immobilized lipase, Lipozyme TL IM, was used to catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f534e31e2801d59e00de11e17988160
https://doi.org/10.1016/j.bej.2007.10.019
https://doi.org/10.1016/j.bej.2007.10.019