Vessel fractional flow reserve in assessment of non-culprit lesions in ST elevation myocardial infarction

Autor: Chun Chin Chang, Ming Ju Chuang, Yin Hao Lee, Yi Lin Tsai, Ya Wen Lu, Ruey Hsing Chou, Cheng Hsueh Wu, Tse Min Lu, Po Hsun Huang, Shing Jong Lin

Publikováno v: Open Heart, Vol 8, Iss 2 (2021)

Objectives We sought to evaluate the physiology of non-culprit lesions by using vessel fractional flow reserve (vFFR) among patients with ST elevation myocardial infarction (STEMI) and multivessel disease (MVD).Methods From January 2017 to December 2

Externí odkaz: https://doaj.org/article/b1901b093ab046e0be67fb03828b45ab

Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework

Autor: Nguan Soon Tan, Mintu Pal, Huizhi Chen, Lay Poh Tan, Bae Hoon Lee, Justin Yin Hao Lee, Yun Sheng Yip

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports

Cancer cells undergoing epithelial-mesenchymal transition (EMT) acquire stem cell-like phenotype associated with malignant behaviour, chemoresistance, and relapse. Current two-dimensional (2D) in-vitro culture models of tumorigenesis are inadequate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bf5f1f4a5ae5c845e9d5482a85de5e
http://link.springer.com/article/10.1038/s41598-019-45384-9

Machine learning of treadmill exercise test to improve selection for testing for coronary artery disease

Autor: Chen Huan Chen, Yin-Hao Lee, Hao Min Cheng, Tsai Tsung-Hsien, Chern-En Chiang, Chi-Jung Huang, Jun-Hong Chen

Publikováno v: Atherosclerosis. 340

The high false-positive rate of the treadmill exercise test (TET) may lead to unnecessary invasive coronary angiography. We aimed to develop a machine learning-based algorithm to improve the diagnostic performance of TET.Study included 2325 patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7b980e0dcf052a89f2d368bde30bc8
https://pubmed.ncbi.nlm.nih.gov/34871817

Risk of ischemic stroke in patients with end-stage renal disease receiving peritoneal dialysis with new-onset atrial fibrillation

Autor: Szu Yuan Li, Yu Wen Su, Jaw Wen Chen, Yin Hao Lee, Yung Tai Chen, Chun Chin Chang, Shing Jong Lin, Chien Yi Hsu, Po Hsun Huang, Chin Chou Huang, Hsin Bang Leu

Publikováno v: Journal of the Chinese Medical Association : JCMA. 83(12)

Background The clinical effect of atrial fibrillation (AF)-related ischemic cardiovascular events in patients undergoing peritoneal dialysis (PD) remains uncertain. This study aimed to investigate the risk of ischemic events in patients undergoing PD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d1c32bc8049575cdddd3d49960875d
https://pubmed.ncbi.nlm.nih.gov/32858549

Deficiency in fibroblast PPARβ/δ reduces nonmelanoma skin cancers in mice

Autor: Yin Hao Lee, Nguan Soon Tan, Hong Sheng Cheng, Zun Siong Low, Jeremy Soon Kiat Chan, Ming Keat Sng, Benjamin Jia Juin Leong, Walter Wahli, Eddie Han Pin Tan, Damien Chua, Mark Wei Yi Tan, Mintu Pal, Xiaomeng Wang, Yun Sheng Yip

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, In press, ⟨10.1038/s41418-020-0535-y⟩
Cell Death Differ

The incidence of nonmelanoma skin cancer (NMSC) has been increasing worldwide. Most studies have highlighted the importance of cancer-associated fibroblasts (CAFs) in NMSC progression. However much less is known about the communication between normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b79431bc8658ad77b9e96b23a36e31
https://hdl.handle.net/10356/144773