Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63-specific ubiquitination.

Autor: Ding MY; Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao SAR, China., Ning C; SUSTech Academy for Advanced Interdisciplinary Studies and Department of Chemistry, and Shenzhen Grubbs Institute, Southern University of Science and Technology, Shenzhen, China., Chen SR; Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao SAR, China., Yin HR; Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao SAR, China., Xu J; SUSTech Academy for Advanced Interdisciplinary Studies and Department of Chemistry, and Shenzhen Grubbs Institute, Southern University of Science and Technology, Shenzhen, China., Wang Y; Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao SAR, China.; Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Macao SAR, China.; Minister of Education Science Center for Precision Oncology, University of Macau, Macao SAR, China.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Sep 01. Date of Electronic Publication: 2024 Sep 01.

Targeting the NLRP3 inflammasome as new therapeutic avenue for inflammatory bowel disease.

Autor: Chen QL; State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, PR China; Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Avenida da Universidade, Taipa, Macao SAR, PR China., Yin HR; Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Avenida da Universidade, Taipa, Macao SAR, PR China., He QY; Minister of Education Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou 510632, PR China. Electronic address: tqyhe@jnu.edu.cn., Wang Y; Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Avenida da Universidade, Taipa, Macao SAR, PR China; Minister of Education Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou 510632, PR China. Electronic address: emilyywang@um.edu.mo.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jun; Vol. 138, pp. 111442. Date of Electronic Publication: 2021 Mar 02.

Genome-wide screening identifies oncofetal lncRNA Ptn-dt promoting the proliferation of hepatocellular carcinoma cells by regulating the Ptn receptor.

Autor: Huang JF; Department of Medical Genetics, Second Military Medical University, 200433, Shanghai, China.; Department of Clinical Genetics, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China., Jiang HY; Department of Gastroenterology, Zhongshan Hospital, Fudan University, 200032, Shanghai, China., Cai H; Department of General Surgery, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China., Liu Y; Department of Medical Genetics, Second Military Medical University, 200433, Shanghai, China., Zhu YQ; Department of Medical Genetics, Second Military Medical University, 200433, Shanghai, China., Lin SS; Center of Reproductive Medicine, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China., Hu TT; Center of Reproductive Medicine, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China., Wang TT; Department of Medical Genetics, Second Military Medical University, 200433, Shanghai, China.; Department of Clinical Genetics, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China., Yang WJ; Department of Medical Genetics, Second Military Medical University, 200433, Shanghai, China., Xiao B; Department of Medical Genetics, Second Military Medical University, 200433, Shanghai, China., Sun SH; Department of Medical Genetics, Second Military Medical University, 200433, Shanghai, China.; Department of Clinical Genetics, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China., Ma LY; Department of General Surgery, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China. malydr@163.com., Yin HR; Center of Reproductive Medicine, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China. topyin@126.com., Wang F; Department of Medical Genetics, Second Military Medical University, 200433, Shanghai, China. wfsjz@163.com.; Department of Clinical Genetics, Changhai Hospital, Second Military Medical University, 200433, Shanghai, China. wfsjz@163.com.

Publikováno v: Oncogene [Oncogene] 2019 May; Vol. 38 (18), pp. 3428-3445. Date of Electronic Publication: 2019 Jan 14.

Family participatory clown therapy in venipuncture in hospitalized children: A non-randomized controlled trial.

Autor: Chen, Tianyu¹ (AUTHOR), Chen, Qiying² (AUTHOR), Lin, Zhenhua² (AUTHOR), Ye, Jingfang¹ (AUTHOR) 116414063@qq.com

Publikováno v: PLoS ONE. 7/25/2024, Vol. 19 Issue 7, p1-16. 16p.

Integrated transcriptome and microRNA analysis reveals molecular responses to high-temperature stress in the liver of American shad (Alosa sapidissima).

Autor: Liu, Ying¹ (AUTHOR), Liang, Zhengyuan¹ (AUTHOR), Li, Yulin¹ (AUTHOR), Zhu, Wenbin² (AUTHOR), Feng, Bingbing³ (AUTHOR), Xu, Wei³ (AUTHOR), Fu, Jianjun² (AUTHOR), Wei, Panpan⁴ (AUTHOR), Luo, Mingkun^1,2 (AUTHOR) luomingkun@ffrc.cn, Dong, Zaijie^1,2 (AUTHOR) dongzj@ffrc.cn

Publikováno v: BMC Genomics. 7/1/2024, Vol. 25, p1-14. 14p.