Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yin H. Lai"'
Autor:
Glen Spraggon, Smith Jeffrey M, Chianelli Donatella, Advait Nagle, Christian Wiesmann, Xiaodong Liu, Yongping Xie, Richard J. Sciotti, Todd Groessl, Kevin Johnson, Xianzhong Liu, Celine Be, Christopher Thompson, Yin H. Lai, Jan Jiricek, Patrick J Rudewicz, Brandon S. Pybus, Casey J. N. Mathison, Valentina Molteni, Honnappa Srinivas, Richard Glynne, Jaime Ballard, Agnes Biggart, Diana Caridha, Andreas Hein, Ashley Mitchell Berman, Mu-Yun Gao, Lauren C. Davis, Michael Shapiro, Michael Gibney, Yen Liang Chen, Vince Yeh, Fabian K. Eggimann, Badry Bursulaya, Mara Kreishman-Deitrick, Lerario Isabelle K, Fang Liang, Shilpi Khare, Wendy Richmond, Srinivasa P. S. Rao, Frantisek Supek, Tove Tuntland, Alexandre Luneau
Publikováno v:
Journal of Medicinal Chemistry
Visceral leishmaniasis is responsible for up to 30,000 deaths every year. Current treatments have shortcomings that include toxicity and variable efficacy across endemic regions. Previously, we reported the discovery of GNF6702, a selective inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37584f6654d3dc34b0710ef1ed444634
https://doi.org/10.1021/acs.jmedchem.0c00499
https://doi.org/10.1021/acs.jmedchem.0c00499
Autor:
Advait Nagle, Ben G. Wen, Srinivasa P. S. Rao, Monique Stinson, Glenn C. Federe, Richard Glynne, Yin H. Lai, Ianne C. Rivera, Ansgar Brock, Michael Shapiro, Hazel X. Y. Koh, John D. Venable, Jaime Ballard, J. Robert Gillespie, Badry Bursulaya, Glen Spraggon, Xianzhong Liu, Mu-Yun Gao, Vince Yeh, Tove Tuntland, Fang Liang, S. Whitney Barnes, Todd Groessl, Shilpi Khare, Elmarie Myburgh, Agnes Biggart, Lauren C. Davis, Jocelyn Tan, Pranab Mishra, Frantisek Supek, Casey J. N. Mathison, Valentina Molteni, Jeremy C. Mottram, Frederick S. Buckner, John R. Walker
Publikováno v:
Nature
Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide and lead to more than 50,000 deaths annually1. The diseases are caused by infection with the kinetoplastid parasites Trypanosoma cruzi, Leishmania spp. and Trypano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bc027b1d63c94a64adf691d28ee40c
http://europepmc.org/articles/PMC5161665
http://europepmc.org/articles/PMC5161665