Nonsteroidal Anti-Inflammatory Drugs Reduce Second Cancer Risk in Patients With Breast Cancer: A Nationwide Population-Based Propensity Score-Matched Cohort Study in Taiwan

Autor: Yin-Che Lu, Pin-Tzu Chen, Mei-Chen Lin, Che-Chen Lin, Shi-Heng Wang, Yi-Jiun Pan

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce mortality in patients with cancer, especially breast cancer, but their influence on second cancer risk is uncertain. This study aimed to examine whether NSAID use is associated with second cancer r

Externí odkaz: https://doaj.org/article/ba70d77f9b844b3983aa3c3cc979bfcd

Older Age and High Serum Ferritin Levels Associated With the Risk of Chronic Cytopenia in Hemodialysis Patients

Autor: Yu-Ting Lee, Wei-Yu Wang, Chin-Ho Kuo, Ming-Yang Lee, Yin-Che Lu, Chih-Yen Hsiao, Yueh-Han Hsu, Peir-Haur Hung

Publikováno v: Frontiers in Medicine, Vol 7 (2020)

Leukopenia or thrombocytopenia is sometimes observed in end-stage renal disease (ESRD) patients, but the association between chronic leukopenia or thrombocytopenia and hemodialysis (HD) is still unclear. We aimed to investigate the incidence of chron

Externí odkaz: https://doaj.org/article/f55ba75433884d789ff27ea212651640

Reversine Induced Multinucleated Cells, Cell Apoptosis and Autophagy in Human Non-Small Cell Lung Cancer Cells.

Autor: Yin-Che Lu, Ying-Ray Lee, Ji-Der Liao, Ching-Yen Lin, Yih-Yuan Chen, Ping-Tzu Chen, Ya-Shih Tseng

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0158587 (2016)

Reversine, an A3 adenosine receptor antagonist, has been shown to induce differentiated myogenic-lineage committed cells to become multipotent mesenchymal progenitor cells. We and others have reported that reversine has an effect on human tumor suppr

Externí odkaz: https://doaj.org/article/7da4edfd76b347d894eb2c037e632803

Rutin‐protected BisGMA ‐induced cytotoxicity, genotoxicity, and apoptosis in macrophages through the reduction of the mitochondrial apoptotic pathway and induction of antioxidant enzymes

Autor: Yu-Chao Chang, Min-Wei Lee, Chun-Hung Su, Yu-Hsiang Kuan, Yin-Che Lu, Fu-Mei Huang, Shiuan-Shinn Lee, Dom-Gene Tu, Kun-Lin Yeh, Sheng-Wen Wu, Chen-Yu Chiang

Publikováno v: Environmental Toxicology. 36:45-54

Bisphenol-A-glycidyldimethacrylate (BisGMA) is a resin monomer frequently used in dentin restorative treatments. The leakage of BisGMA monomer from BisGMA-based polymeric resins can lead to cytotoxicity in macrophages. Rutin has various beneficial bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93320922b07ec33f02e14ef8fed90a4
https://doi.org/10.1002/tox.23009

Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model

Autor: Shih Han Chen, Sara Collins, Shu-Fen Wu, Jui Ming Sun, Deching Chang, Weijun Wang, Hao Fang Chang, Thomas C. Chen, Bing Mao Chen, Yin Che Lu, Chien-Kuo Tai, Sheng Che Lin, Noriyuki Kasahara, Hsin Ell Wang

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 4
International journal of molecular sciences, vol 21, iss 4
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1433 (2020)

Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV) was previously shown to be highly effective in killing glioma cells both in culture and in vivo. To avoid receptor interference and enab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429231c40a824996e94b98b192450c4d