Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Yin Chao Tseng"'
Autor:
Ashley Dan, Haresh Vaswani, Alice Šimonová, Aleksandra Grząbka-Zasadzińska, Jingzhe Li, Koyel Sen, Shubhajit Paul, Yin-Chao Tseng, Rohit Ramachandran
Publikováno v:
International Journal of Pharmaceutics: X, Vol 6, Iss , Pp 100188- (2023)
In this study, the torque profiles of heterogeneous granulation formulations with varying powder properties in terms of particle size, solubility, deformability, and wettability, were studied, and the feasibility of identifying the end-point of the g
Externí odkaz:
https://doaj.org/article/ada886458cd14d5a81552ea64d15f09c
Autor:
Tipu, Sultan, Shubhajit, Paul, Enamul Hasan, Rozin, Yin-Chao, Tseng, Michael C F, Bazzocchi, Cetin, Cetinkaya
Publikováno v:
AAPS PharmSciTech. 24
Due to their constituent powders, the materials of advanced compressed oral solid dosage (OSD) forms are micro-composites and strongly visco-elastic at macro- and micro-length scales. The disintegration, drug release, and mechanical strength of OSD f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9773023c344c355e1d43d6d3ff4f10
https://doi.org/10.1208/s12249-022-02483-7
https://doi.org/10.1208/s12249-022-02483-7
Autor:
Tipu Sultan, Shubhajit Paul, Enamul Hasan Rozin, Christian Canino, Yin-Chao Tseng, Cetin Cetinkaya
Publikováno v:
International journal of pharmaceutics. 623
In compacted materials, elastic anisotropy coupled with residual stresses could play a determining role in the manifestation of various types of defects such as capping and lamination, as it creates shear planes/bands and temporal relaxation. This in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ee9c5472de05eb925fea8182187a70
https://pubmed.ncbi.nlm.nih.gov/35724823
https://pubmed.ncbi.nlm.nih.gov/35724823
Autor:
Ryan M Fryer, Mita Patel, Xiaomei Zhang, Katja S Baum-Kroker, Akalushi Muthukumarana, Brian Linehan, Yin-Chao Tseng
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Establishing a wide therapeutic index (TI) for pre-clinical safety is important during lead optimization (LO) in research, prior to clinical development, although is often limited by a molecules physiochemical characteristics. Recent advances in the
Externí odkaz:
https://doaj.org/article/f23ed065d90641de85aa0a48e9ca1c0d
Autor:
Shubhajit Paul, Yin-Chao Tseng
Publikováno v:
Journal of Pharmaceutical Sciences.
Capping is a mechanical defect in tablets, which is attributed to multiple factors including intrinsic material properties and tableting conditions. A suitable non-destructive approach using acoustically derived elastic modulus has showed distinctive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c5409671aecf55e906341e72a2f268
https://doi.org/10.1016/j.xphs.2021.02.032
https://doi.org/10.1016/j.xphs.2021.02.032
Autor:
Yin-Chao Tseng, Shubhajit Paul
Publikováno v:
Journal of pharmaceutical sciences. 110(6)
The evolution of tablet strength is mainly influenced by deformability (bonding area) and strength of intermolecular interactions (bonding strength) from the intrinsic material properties and tableting process, respectively. Therefore, understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201585d73e5448d823b12943b94e68dd
https://pubmed.ncbi.nlm.nih.gov/33744275
https://pubmed.ncbi.nlm.nih.gov/33744275
Autor:
Kathleen Hoyt, Kim Fletcher, Christian Harcken, Steven Richard Brunette, T. Gregg Davis, Delphine Collin, Ryan M. Fryer, Robert Sibley, Thomas Wieckowski, Jörg P Hehn, Dustin Smith, Yin-Chao Tseng, Stanley Kugler, Csengery Johanna, Donald Souza, Liang Shuang, Michael Robert Turner, Mark E. Labadia, Donna Terenzio, Anita L. Wayne, Mark Panzenbeck, Wu Lifen, Robert Hughes
Publikováno v:
ACS Med Chem Lett
[Image: see text] The interleukin (IL)-23/T helper (Th)17 axis plays a critical role in autoimmune diseases, and there is an increasing number of biologic therapies that target IL-23 and IL-17. The transcription factor retinoic acid receptor-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86af9280bb7f85b4a15b0ef59af3fcc
https://pubmed.ncbi.nlm.nih.gov/33488976
https://pubmed.ncbi.nlm.nih.gov/33488976
Publikováno v:
International journal of pharmaceutics. 599
Capping is the frequently observed mechanical defect in tablets arising from the sub-optimal selection of the formulation composition and their robustness of response toward process parameters. Hence, overcoming capping propensity based on the unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59bafdbe39448ce4515f99656252fa79
https://pubmed.ncbi.nlm.nih.gov/33662471
https://pubmed.ncbi.nlm.nih.gov/33662471
Autor:
Xiaorong He, Leon Schultz, Daniela Schröder, Martin Maus, Schwabe Robert J, Ecevit Bilgili, Pavol Rajniak, Yin Chao Tseng, Hossein Amini, Gulsad Kucuk
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 151
Moisture plays a major role in determining the attributes of granules prepared by fluidized bed granulation (FBG). Here, a semi-theoretical droplet-based evaporation rate model was developed and incorporated into moisture mass-enthalpy balances to si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843ebe13f349485d336e7f21ce6be80e
https://pubmed.ncbi.nlm.nih.gov/32304867
https://pubmed.ncbi.nlm.nih.gov/32304867
Publikováno v:
International Journal of Pharmaceutics. 491:208-217
A central composite design approach was applied to study the effect of polymer concentration, inlet temperature and air flow rate on the spray drying process of the Büchi B-90 nano spray dryer (B-90). Hypromellose acetate succinate-LF was used for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d85536e9c53da98849a66b38aecfa5
https://doi.org/10.1016/j.ijpharm.2015.06.006
https://doi.org/10.1016/j.ijpharm.2015.06.006