Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Yin‐Ming Kuo"'
Engaging student opinions on vaccine development innovation: Experiences from a 'Shark Tank' project
Autor:
Jeffrey S. Barrett, Jeffrey M. Skolnik, Mary Ingram, Yin‐Ming Kuo, Ann E. Metzloff, Ruizhe Jin, Yuanhan Wu, Nik Kroushl
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract A graduate course on vaccine development challenged students to propose concepts to improve upon current vaccine development paradigms in the context of a “Shark Tank‐style” format where students were asked to develop an abbreviated bu
Externí odkaz:
https://doaj.org/article/827811e1583e479aaba38c98a1c05be4
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 15, Iss , Pp 15-21 (2018)
Elevated plasma total homocysteine (tHcy) is associated with a number of human diseases including coronary artery disease, stroke, osteoporosis and dementia. It is highly correlated with intracellular S-adenosylhomocysteine (SAH). Since SAH is a stro
Externí odkaz:
https://doaj.org/article/e9d92253faa54cf4bcbe3f111c3f2047
Autor:
Steven Zhao, AnnMarie Torres, Ryan A. Henry, Sophie Trefely, Martina Wallace, Joyce V. Lee, Alessandro Carrer, Arjun Sengupta, Sydney L. Campbell, Yin-Ming Kuo, Alexander J. Frey, Noah Meurs, John M. Viola, Ian A. Blair, Aalim M. Weljie, Christian M. Metallo, Nathaniel W. Snyder, Andrew J. Andrews, Kathryn E. Wellen
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 1037-1052 (2016)
Mechanisms of metabolic flexibility enable cells to survive under stressful conditions and can thwart therapeutic responses. Acetyl-coenzyme A (CoA) plays central roles in energy production, lipid metabolism, and epigenomic modifications. Here, we sh
Externí odkaz:
https://doaj.org/article/1368c98dfbae4b1085e1112de5ae4ed8
Autor:
Rajesh K Yadav, Carolyn M Jablonowski, Alfonso G Fernandez, Brandon R Lowe, Ryan A Henry, David Finkelstein, Kevin J Barnum, Alison L Pidoux, Yin-Ming Kuo, Jie Huang, Matthew J O’Connell, Andrew J Andrews, Arzu Onar-Thomas, Robin C Allshire, Janet F Partridge
Publikováno v:
eLife, Vol 6 (2017)
Recurrent somatic mutations of H3F3A in aggressive pediatric high-grade gliomas generate K27M or G34R/V mutant histone H3.3. H3.3-G34R/V mutants are common in tumors with mutations in p53 and ATRX, an H3.3-specific chromatin remodeler. To gain insigh
Externí odkaz:
https://doaj.org/article/6f07b04184fd448199fb62c77f4d0ff3
Discordant Effects of Putative Lysine Acetyltransferase Inhibitors in Biochemical and Living Systems
Autor:
Ryan A. Henry, Yin-Ming Kuo, Zarek S. Siegel, Timothy J. Yen, Jennifer Rhodes, Erika A. Taylor, Andrew J. Andrews
Publikováno v:
Cells, Vol 8, Iss 9, p 1022 (2019)
Lysine acetyltransferases (KATs) are exquisitely fine-tuned to target specific lysine residues on many proteins, including histones, with aberrant acetylation at distinct lysines implicated in different pathologies. However, researchers face a lack o
Externí odkaz:
https://doaj.org/article/3613f48c79154f9f9fedcc3e801bc7ea
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118516 (2015)
In Saccharomyces cerevisiae, Rtt109, a lysine acetyltransferase (KAT), associates with a histone chaperone, either Vps75 or Asf1. It has been proposed that these chaperones alter the selectivity of Rtt109 or which residues it preferentially acetylate
Externí odkaz:
https://doaj.org/article/bfdfea5af66d43f2b00a5d01cc355a2c
Autor:
Yin-Ming Kuo, Andrew J Andrews
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54896 (2013)
Lysine acetyltransferases (KATs) play a unique role in regulating gene transcription as well as maintaining the epigenetic state of the cell. KATs such as Gcn5 and p300/CBP can modify multiple residues on a single histone; however, order and specific
Externí odkaz:
https://doaj.org/article/64b97b1eaf634762b5cf192731d9ec39
Correction: Quantitating the Specificity and Selectivity of Gcn5-Mediated Acetylation of Histone H3.
Autor:
Yin-Ming Kuo, Andrew J. Andrews
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/92c0c7fd16054cb58570715a8a9540bd
Autor:
Yin-Ming Kuo, 郭殷銘
90
In order to assess the safety of a underground radwaste repository, reactive transport models suitable for evaluating the fate and transport of radionuclides need to be established based on experimental observation and analysis. The goal of t
In order to assess the safety of a underground radwaste repository, reactive transport models suitable for evaluating the fate and transport of radionuclides need to be established based on experimental observation and analysis. The goal of t
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/24808068993747696664
Autor:
Zeng-Jie Yang, Tom Curran, Igor Astsaturov, Andrew J. Andrews, Jessica M. Y. Ng, Brian L. Egleston, Fang Du, Yin-Ming Kuo, Suraj Peri, Li Zhang, Renata E. Gordon
Simvastatin inhibits MB cell proliferation in Ptch1+/- mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a14c07bd9f06514e95b6227dcf4546
https://doi.org/10.1158/1078-0432.22461666
https://doi.org/10.1158/1078-0432.22461666