Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Yin‐Hu Wang"'
Autor:
Fangming Zhu, Ryan J. McMonigle, Andrew R. Schroeder, Xianyou Xia, David Figge, Braxton D. Greer, Edahí González-Avalos, Diego O. Sialer, Yin-Hu Wang, Kelly M. Chandler, Adam J. Getzler, Emily R. Brown, Changchun Xiao, Olaf Kutsch, Yohsuke Harada, Matthew E. Pipkin, Hui Hu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Follicular helper T (Tfh) cells are essential for germinal center (GC) B cell responses. However, it is not clear which PD-1+CXCR5+Bcl6+CD4+ T cells will differentiate into PD-1hiCXCR5hiBcl6hi GC-Tfh cells and how GC-Tfh cell differentiation
Externí odkaz:
https://doaj.org/article/35c086446d634d7882db802bef9f3af3
Autor:
Scott M Emrich, Ryan E Yoast, Xuexin Zhang, Adam J Fike, Yin-Hu Wang, Kristen N Bricker, Anthony Y Tao, Ping Xin, Vonn Walter, Martin T Johnson, Trayambak Pathak, Adam C Straub, Stefan Feske, Ziaur SM Rahman, Mohamed Trebak
Publikováno v:
eLife, Vol 12 (2023)
The essential role of store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions in B
Externí odkaz:
https://doaj.org/article/5b4624a722da497c9f2661a9b380baec
Autor:
Marilena Letizia, Yin‐Hu Wang, Ulrike Kaufmann, Lorenz Gerbeth, Annegret Sand, Max Brunkhorst, Patrick Weidner, Jörn Felix Ziegler, Chotima Böttcher, Stephan Schlickeiser, Camila Fernández, Megumi Yamashita, Kenneth Stauderman, Katherine Sun, Désirée Kunkel, Murali Prakriya, IBDome Researchers, Ashley Sanders, Britta Siegmund, Stefan Feske, Carl Weidinger
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 9, Pp n/a-n/a (2022)
Abstract Inflammatory bowel disease (IBD) is characterized by dysregulated intestinal immune responses. Using mass cytometry (CyTOF) to analyze the immune cell composition in the lamina propria (LP) of patients with ulcerative colitis (UC) and Crohn'
Externí odkaz:
https://doaj.org/article/997a99d779c54eab8e997f08e05290f9
Autor:
Martin Vaeth, Yin-Hu Wang, Miriam Eckstein, Jun Yang, Gregg J. Silverman, Rodrigo S. Lacruz, Kasthuri Kannan, Stefan Feske
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Regulatory T (Treg) cells are important for maintaining immune homeostasis. Here the authors show that STIM1 and STIM2, which activate the Ca2+ channel ORAI1, are essential for the differentiation of peripheral Treg cells into tissue-resident and fol
Externí odkaz:
https://doaj.org/article/0300d7db026b4d60913b2983240f24ef
Autor:
Wei Yang, Yuan Yao, Yan-Qing Yang, Fang-Ting Lu, Liang Li, Yin-Hu Wang, Takahiko Nakajima, Koichi Tsuneyama, William M Ridgway, M Eric Gershwin, Zhe-Xiong Lian
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105351 (2014)
IFN-γ is a signature Th1 cell associated cytokine critical for the inflammatory response in autoimmunity with both pro-inflammatory and potentially protective functions. IL-17A is the hallmark of T helper 17 (Th17) cell subsets, produced by γδT, C
Externí odkaz:
https://doaj.org/article/7b9e2cab18514d87b585017acf664a97
Autor:
Scott M Emrich, Ryan E Yoast, Xuexin Zhang, Adam J Fike, Yin-Hu Wang, Kristen N Bricker, Anthony Y Tao, Ping Xin, Vonn Walter, Martin T Johnson, Trayambak Pathak, Adam C Straub, Stefan Feske, Ziaur SM Rahman, Mohamed Trebak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6949a79f1dcda70f27e94b25331860
https://doi.org/10.7554/elife.84708.sa2
https://doi.org/10.7554/elife.84708.sa2
Autor:
Yin-Hu Wang, Lucile Noyer, Sascha Kahlfuss, Dimitrius Raphael, Anthony Y. Tao, Ulrike Kaufmann, Jingjie Zhu, Marisa Mitchell-Flack, Ikjot Sidhu, Fang Zhou, Martin Vaeth, Paul G. Thomas, Sean P. Saunders, Kenneth Stauderman, Maria A. Curotto de Lafaille, Stefan Feske
Publikováno v:
Science Advances. 8
T cell activation and function depend on Ca2+signals mediated by store-operated Ca2+entry (SOCE) through Ca2+release–activated Ca2+(CRAC) channels formed by ORAI1 proteins. We here investigated how SOCE controls T cell function in pulmonary inflamm
Autor:
Scott M. Emrich, Ryan E. Yoast, Xuexin Zhang, Adam J. Fike, Yin-Hu Wang, Kristen N. Bricker, Anthony Tao, Ping Xin, Vonn Walter, Martin T. Johnson, Trayambak Pathak, Adam C. Straub, Stefan Feske, Ziaur S.M. Rahman, Mohamed Trebak
The essential role of store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions in B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e396a01d7ac2ecf4a599e7218f0ccbf
https://doi.org/10.1101/2022.05.06.490918
https://doi.org/10.1101/2022.05.06.490918
Autor:
Liwei Wang, Lucile Noyer, Yin-Hu Wang, Anthony Y. Tao, Wenyi Li, Jingjie Zhu, Pedro Saavedra, Syed T. Hoda, Jun Yang, Stefan Feske
Publikováno v:
The Journal of general physiology. 154(10)
Ca2+ signals regulate the function of many immune cells and promote immune responses to infection, cancer, and autoantigens. Ca2+ influx in immune cells is mediated by store-operated Ca2+ entry (SOCE) that results from the opening of Ca2+ release-act
Autor:
Emrich, Scott M., Yoast, Ryan E., Xuexin Zhang, Fike, Adam J., Yin-Hu Wang, Bricker, Kristen N., Tao, Anthony Y., Ping Xin, Walter, Vonn, Johnson, Martin T., Pathak, Trayambak, Straub, Adam C., Feske, Stefan, Rahman, Ziaur S. M., Trebak, Mohamed
Publikováno v:
eLife; 3/9/2023, p1-33, 33p