Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Yimin, Jia"'
Autor:
Yimin Jia, Cun Sun, Ting Chen, Hui Zhu, Tianrui Wang, Yan Ye, Xing Luo, Xiaoqiang Zeng, Yun Yang, Hao Zeng, Quanming Zou, Enqiang Liu, Jieping Li, Hongwu Sun
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Acute myeloid leukemia (AML) is an invasive hematopoietic malignancy caused by excessive proliferation of myeloblasts. Classical chemotherapies and cell transplantation therapies have remarkable efficacy in AML treatment; however, 30–40% o
Externí odkaz:
https://doaj.org/article/5344dd2aa046458e9dcaf9bf8ef3a2a1
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-12 (2023)
Abstract In the process of inflammatory activation, macrophages exhibit lipid metabolism disorders and accumulate lipid droplets. Kupffer cells (KCs) are the resident hepatic macrophage with critical defense functions in the pathogenesis of several t
Externí odkaz:
https://doaj.org/article/619ede46d48f45d299c0288068f873fd
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
ObjectiveChronic stress leads to a high circulating level of glucocorticoids, which disrupts lipid metabolism and causes non-alcoholic fatty liver disease in mice and humans. Meanwhile, bile acid (BA), a class of metabolites initially synthesized in
Externí odkaz:
https://doaj.org/article/f6125baf1ee84cf68faa728d36634a04
Publikováno v:
Interdisciplinary Medicine, Vol 1, Iss 2, Pp n/a-n/a (2023)
Abstract BRCA1/2 gene mutations, which result in a dysfunction of homologous recombination repair, have been discovered in at least 5% of breast cancer (BC) patients with the increase in BC incidence in recent years. PARP inhibitors (PARPis), the fir
Externí odkaz:
https://doaj.org/article/e814a7ed07ac47cb91a9e7c846383bea
Autor:
Yang Yang, Wanwan Han, Aijia Zhang, Mindie Zhao, Wei Cong, Yimin Jia, Deyun Wang, Ruqian Zhao
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Corticotropin-releasing hormone (CRH), the major secretagogue of the hypothalamic-pituitary-adrenal (HPA) axis, is intricately intertwined with the clock genes to regulate the circadian rhythm of various body functions. N6-methyla
Externí odkaz:
https://doaj.org/article/9c46039defaa45ebabc8e2db9227ba27
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Background Glucocorticoid receptor (GR) mediated corticosterone-induced fatty liver syndrome (FLS) in the chicken by transactivation of Fat mass and obesity associated gene (FTO), leading to demethylation of N6-methyladenosine (m6A) and post
Externí odkaz:
https://doaj.org/article/ccb34693258742b080e1b56feaf00134
Autor:
Yanwen Zhang, Li Ren, Xiaoxiao Sun, Zhilong Zhang, Jie Liu, Yining Xin, Jianmin Yu, Yimin Jia, Jinghao Sheng, Guo-fu Hu, Ruqian Zhao, Bin He
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Paternal environmental inputs can influence various phenotypes in offspring, with important implications for basic biology and public health. Here the authors show that Ang-mediated biogenesis of 5′-tsRNAs in sperm contributes to paternal inflammat
Externí odkaz:
https://doaj.org/article/53aabb0785ef48efaf1f35fe61011e0a
Autor:
Yue Feng, Haibo Dong, Bo Sun, Yun Hu, Yang Yang, Yimin Jia, Longfei Jia, Xiang Zhong, Ruqian Zhao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 839-856 (2021)
Background and Aims: Transforming growth factor β1 (TGF-β1) secreted from activated Kupffer cells (KC) promotes the progression of nonalcoholic steatohepatitis (NASH) to liver fibrosis. N6-methyladenosine (m6A) RNA modification participates in vari
Externí odkaz:
https://doaj.org/article/7a5c5e289bf34ed0923db46d3e67dc46
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Background: There has been a recent appreciation that some metabolic enzymes can profoundly influence the nature of the immune response produced in macrophages. However, the role of mitochondrial phosphoenolpyruvate carboxykinase (PCK2) in immune res
Externí odkaz:
https://doaj.org/article/ae556057db294e1fb5ce8f8a7321f598
Autor:
Yue Feng, Shihui Guo, Yulan Zhao, Haibo Dong, Jiayu Qian, Yun Hu, Lei Wu, Yimin Jia, Ruqian Zhao
Publikováno v:
Cell Death & Differentiation. 30:1211-1220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4d5aa8a625388078c3e03ae43b4db4d
https://doi.org/10.1038/s41418-023-01130-3
https://doi.org/10.1038/s41418-023-01130-3