Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Yimei Lu"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundAn increasing body of evidence suggests that neuroinflammation is one of the key drivers of late-onset Alzheimer’s disease (LOAD) pathology. Due to the increased permeability of the blood–brain barrier (BBB) in older adults, peripheral
Externí odkaz:
https://doaj.org/article/cc2d6377d5c74bce8ed45b6dc11beb6b
Autor:
Wenwen Ou, Yumeng Yang, Yafei Chen, Yunjing Li, Siqi Yang, Yimei Lu, Liang Li, Mei Huang, Mohan Ma, Guanyi Lv, Xiaotian Zhao, Yaqi Qing, Yumeng Ju, Yan Zhang
Publikováno v:
Child and Adolescent Psychiatry and Mental Health, Vol 17, Iss 1, Pp 1-10 (2023)
Abstract Background Parenting styles and the associated proximal psychological factors are suggested to increase suicidal risks in adolescents. However, how the two factors interact and confer risks on the emergence of adolescent suicidal thoughts re
Externí odkaz:
https://doaj.org/article/f167d6eced9843cda371190f47be3fe0
Autor:
Yan Zhang, Jin Liu, Mei Huang, Liang Li, Yumeng Ju, Bangshan Liu, Shuyin Xu, Xiyu Wei, Wenwen Ou, Mohan Ma, Guanyi Lv, Xiaotian Zhao, Yaqi Qin, Yunjing Li, Siqi Yang, Yimei Lu, Yafei Chen, Junwu Liu
Publikováno v:
General Psychiatry, Vol 37, Iss 2 (2024)
Background The co-occurrence of depression and anxiety among adolescents is typically associated with suicide ideation.Aims The study aimed to investigate the symptom-level relationship between suicide ideation and the comorbidity of depression and a
Externí odkaz:
https://doaj.org/article/a7198ef39f2c462f8a892d4bd696972b
Autor:
Davis Cammann, Yimei Lu, Melika J. Cummings, Mark L. Zhang, Joan Manuel Cue, Jenifer Do, Jeffrey Ebersole, Xiangning Chen, Edwin C. Oh, Jeffrey L. Cummings, Jingchun Chen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract A growing body of evidence suggests that dysbiosis of the human gut microbiota is associated with neurodegenerative diseases like Alzheimer’s disease (AD) via neuroinflammatory processes across the microbiota-gut-brain axis. The gut microb
Externí odkaz:
https://doaj.org/article/cf2aa3440ff0428cb92fe6491c96e93c
Autor:
Shuyin Xu, Yafei Chen, Yunjing Li, Siqi Yang, Yimei Lu, Liang Li, Mei Huang, Mohan Ma, Wenwen Ou, Guanyi Lv, Xiaotian Zhao, Yaqi Qin, Yumeng Ju, Yan Zhang, Lingjiang Li
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
ObjectivePrevious studies on the reliability and validity of the Affective Lability Scale short-form (ALS-SF) have only been evaluated in adults, which may not be able to generalize to the adolescent population. We aimed to examine the factor structu
Externí odkaz:
https://doaj.org/article/e7ca5c8110424cf19e529d32dee223c9
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Background. Of all intestinal microbiome-derived metabolites, trimethylamine N-oxide (TMAO) has received increasing attention because of its potent role in colorectal cancer development. Accumulating evidence suggests that TMAO generated by the gut m
Externí odkaz:
https://doaj.org/article/925db3c983154857b49a23b453921327
Autor:
Yang Fang, Xifeng Wang, Danying Yang, Yimei Lu, Gen Wei, Wen Yu, Xing Liu, Qingcui Zheng, Jun Ying, Fuzhou Hua
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The intracellular energy state will alter under the influence of physiological or pathological stimuli. In response to this change, cells usually mobilize various molecules and their mechanisms to promote the stability of the intracellular energy sta
Externí odkaz:
https://doaj.org/article/05e539612c32470291abf50c8c8f845c
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Microglia are the primary resident immune cells of the central nervous system that maintain physiological homeostasis in the brain and contribute to the pathogenesis of many psychiatric disorders and neurodegenerative diseases. Due to the lack of app
Externí odkaz:
https://doaj.org/article/3d2eba451bf44073a00c913fb7707a5a
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract 526-residue FUS functions to self-assemble into reversible droplets/hydrogels, which could be further solidified into pathological fibrils. FUS is intrinsically prone to aggregation, composed of N-terminal low-sequence complexity (LC); RNA-r
Externí odkaz:
https://doaj.org/article/ac31ba6d3f1f4c03806bbf71a176ee51
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000327 (2019)
526-residue Fused in sarcoma (FUS) undergoes liquid-liquid phase separation (LLPS) for its functions, which can further transit into pathological aggregation. ATP and nucleic acids, the universal cellular actors, were shown to modulate LLPS of FUS in
Externí odkaz:
https://doaj.org/article/f6415b2bf0094630bf592e2651194a1f