Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state.

Autor: Barrett TF; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA., Patel B; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA., Khan SM; Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Brain Tumor Immunology and Immunotherapy Program, Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Mullins RDZ; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Yim AKY; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Pugazenthi S; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA., Mahlokozera T; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA., Zipfel GJ; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.; Brain Tumor Center, Washington University School of Medicine/Siteman Cancer Center, St. Louis, MO, USA., Herzog JA; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.; Brain Tumor Center, Washington University School of Medicine/Siteman Cancer Center, St. Louis, MO, USA., Chicoine MR; Department of Neurological Surgery, University of Missouri School of Medicine, Columbia, MO, USA., Wick CC; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.; Brain Tumor Center, Washington University School of Medicine/Siteman Cancer Center, St. Louis, MO, USA., Durakovic N; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.; Brain Tumor Center, Washington University School of Medicine/Siteman Cancer Center, St. Louis, MO, USA., Osbun JW; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA., Shew M; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.; Brain Tumor Center, Washington University School of Medicine/Siteman Cancer Center, St. Louis, MO, USA., Sweeney AD; Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA., Patel AJ; Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA., Buchman CA; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.; Brain Tumor Center, Washington University School of Medicine/Siteman Cancer Center, St. Louis, MO, USA., Petti AA; Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. apetti@mgh.harvard.edu.; Brain Tumor Immunology and Immunotherapy Program, Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. apetti@mgh.harvard.edu., Puram SV; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA. sidpuram@wustl.edu.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA. sidpuram@wustl.edu.; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA. sidpuram@wustl.edu., Kim AH; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA. alberthkim@wustl.edu.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA. alberthkim@wustl.edu.; Brain Tumor Center, Washington University School of Medicine/Siteman Cancer Center, St. Louis, MO, USA. alberthkim@wustl.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jan 12; Vol. 15 (1), pp. 478. Date of Electronic Publication: 2024 Jan 12.

The clinical characteristics of pediatric patients infected by SARS-CoV-2 Omicron variant and whole viral genome sequencing analysis.

Autor: Tsang HF; Department of Clinical Laboratory and Pathology, Hong Kong Adventist Hospital, Hong Kong, China.; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China., Yu ACS; Codex Genetics Limited, Hong Kong, China., Yim AKY; Codex Genetics Limited, Hong Kong, China., Jin N; Codex Genetics Limited, Hong Kong, China., Wu YO; Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Cheng HYL; Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Cheung WL; Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Leung WMS; Department of Clinical Laboratory and Pathology, Hong Kong Adventist Hospital, Hong Kong, China., Lam KW; Department of Clinical Laboratory and Pathology, Hong Kong Adventist Hospital, Hong Kong, China., Hung TN; Department of Clinical Laboratory and Pathology, Hong Kong Adventist Hospital, Hong Kong, China., Chan L; Department of Clinical Laboratory and Pathology, Hong Kong Adventist Hospital, Hong Kong, China., Chiou J; Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Pei XM; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China., Lee OYA; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China., Cho WCS; Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong, China., Wong SCC; Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.

Publikováno v: PloS one [PLoS One] 2023 Mar 10; Vol. 18 (3), pp. e0282389. Date of Electronic Publication: 2023 Mar 10 (Print Publication: 2023).

The diagnostic significance of CDH17-positive circulating tumor cells in patients with colorectal cancer.

Autor: Pei XM; Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong Special Administrative Region, China., Wong HT; Department of Pathology, Kiang Wu Hospital, Macao, Macau Special Administrative Region, China., Ng SSM; Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region, China., Leung WW; Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region, China., Wong YN; Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region, China., Tsang HF; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, Hong Kong Special Administrative Region, China., Chan AKC; Department of Pathology, Queen Elizabeth Hospital, Hong Kong, Hong Kong Special Administrative Region, China., Wong YKE; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, Hong Kong Special Administrative Region, China., Yu ACS; Department of Research and Develpment, Codex Genetics Limited, Hong Kong, Hong Kong Special Administrative Region, China., Yim AKY; Department of Research and Develpment, Codex Genetics Limited, Hong Kong, Hong Kong Special Administrative Region, China., Cho WCS; Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong Special Administrative Region, China., Chan JKC; Department of Pathology, Queen Elizabeth Hospital, Hong Kong, Hong Kong Special Administrative Region, China., Wong KF; Department of Research and Develpment Arbele Limited, Hong Kong, Hong Kong Special Administrative Region, China., Luk JM; Department of Research and Develpment Arbele Limited, Hong Kong, Hong Kong Special Administrative Region, China., Tai WCS; Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong Special Administrative Region, China., Wong SCC; Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong Special Administrative Region, China.; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, Hong Kong Special Administrative Region, China.

Publikováno v: Expert review of molecular diagnostics [Expert Rev Mol Diagn] 2023 Feb; Vol. 23 (2), pp. 171-179. Date of Electronic Publication: 2023 Feb 09.

Disentangling glial diversity in peripheral nerves at single-nuclei resolution.

Autor: Yim AKY; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Wang PL; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Bermingham JR Jr; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Hackett A; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Strickland A; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Miller TM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Ly C; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Mitra RD; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Milbrandt J; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA. jmilbrandt@wustl.edu.

Publikováno v: Nature neuroscience [Nat Neurosci] 2022 Feb; Vol. 25 (2), pp. 238-251. Date of Electronic Publication: 2022 Feb 03.

An update on COVID-19 pandemic: the epidemiology, pathogenesis, prevention and treatment strategies.

Autor: Tsang HF; Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Chan LWC; Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Cho WCS; Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong Special Administrative Region., Yu ACS; Department of Research, Codex Genetics Limited, Hong Kong Special Administrative Region., Yim AKY; Department of Research, Codex Genetics Limited, Hong Kong Special Administrative Region., Chan AKC; Department of Pathology, Queen Elizabeth Hospital, Hong Kong Special Administrative Region., Ng LPW; Department of Pathology, Queen Elizabeth Hospital, Hong Kong Special Administrative Region., Wong YKE; Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Pei XM; Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Li MJW; Department of Research, Codex Genetics Limited, Hong Kong Special Administrative Region., Wong SC; Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong Special Administrative Region.

Publikováno v: Expert review of anti-infective therapy [Expert Rev Anti Infect Ther] 2021 Jul; Vol. 19 (7), pp. 877-888. Date of Electronic Publication: 2020 Dec 29.