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Publikováno v:
Biomolecules & Biomedicine (2024)
The enzyme glutamate-cysteine ligase modifier subunit (GCLM) serves as the initial rate-limiting factor in glutathione (GSH) synthesis. GSH is the preferred substrate for glutathione peroxidase 4 (GPX4), directly impacting its activity and stability.
Externí odkaz:
https://doaj.org/article/034685b021ed4397a7ac18a565c8564d
