Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Yili Ding"'
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-11 (2024)
Abstract As an orally effective benzimidazole anthelmintic agent, fenbendazole was not only widely used in agriculture and animal husbandry to prevent and treat parasites, but also shows anti-cancer effects against several types of cancer, exhibits a
Externí odkaz:
https://doaj.org/article/58b5298b25814c7eb4127460e08aa4c2
Publikováno v:
Molecules, Vol 29, Iss 9, p 1915 (2024)
As a powerful imidazole antifungal drug, ketoconazole’s low solubility (0.017 mg/mL), together with its odor and irritation, limited its clinical applications. The inclusion complex of ketoconazole with randomly methylated β-cyclodextrin was prepa
Externí odkaz:
https://doaj.org/article/bac90496717347e386d8ee8246162b48
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Icariin as a hepatoprotector from Herba epimedii can expand the cardiovascular and cerebral blood vessels, promote hematopoietic functions, enhance the immune system and show anti-liver tumor activities. However, its low solubility (0.02 mg/mL) limit
Externí odkaz:
https://doaj.org/article/f6228846809b4ce29e809bd033656f73
Publikováno v:
Molecules, Vol 28, Iss 21, p 7360 (2023)
Since griseofulvin was marketed as a non-polyene antifungal antibiotic drug in 1958, its poor water solubility has been an issue for its wide applications, and over the last sixty years, many attempts have been made to increase its water solubility;
Externí odkaz:
https://doaj.org/article/ed28d14d06514dcebe58478c3be4a284
Publikováno v:
Molecules, Vol 28, Iss 21, p 7295 (2023)
Albendazole is the preferred deworming drug and has strong insecticidal effects on human and animal helminth parasites, showing remarkable activity against hepatocellular carcinoma and colorectal cancer cells. However, it is classified as being in cl
Externí odkaz:
https://doaj.org/article/70463f8c089f4dcc84e4b534f00bb1db
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 334-343 (2020)
Enrofloxacin, a third-generation fluoroquinolone, is a broad-spectrum antimicrobial drug against a lot of veterinary bacterial diseases. However, bactericidal activity of enrofloxacin is concentration-dependent and its poor aqueous solubility and bit
Externí odkaz:
https://doaj.org/article/e0d55def843a424683bf1ff0b0ea1e03
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 9, Pp 103307- (2021)
An inclusion complex of praziquantel with 2-hydroxypropyl-β-cyclodextrin was designed and prepared by an optimized method and the inclusion complex was characterized by infrared absorption spectral, proton NMR spectral and scanning electron image st
Externí odkaz:
https://doaj.org/article/1c5445e41fb54cb6a836ad5f7de9ee12
Publikováno v:
Polymers, Vol 13, Iss 17, p 2939 (2021)
Cholic acid and galactose or lactose dual conjugated chitosan derivatives were designed and synthesized as potential anti liver cancer drug carriers, their structures were characterized through proton NMR spectra, elemental analysis, size distributio
Externí odkaz:
https://doaj.org/article/9fbb5de3853f474898688c71b941b83c
Publikováno v:
Journal of Chemistry, Vol 2019 (2019)
Fondaparinux (trade name Arixtra) is a safe and efficacious anticoagulant, and it is chemically related to low-molecular-weight heparins such as enoxaparin. Fondaparinux is a synthetic pentasaccharide, and its synthesis is difficult and expensive. Th
Externí odkaz:
https://doaj.org/article/6f88b897124f4120aab85c2139842686
Autor:
Yili, Ding, Bo, Yu, Jianzhou, Zhang, Charles, Ding, Zhiyuan, Zhang, Shufeng, Xu, Lu, Li, Hui, Yu
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 181:104-112
Tilmicosin, as an effective broad-spectrum antibacterial drug, has incomplete absorption and low bioavailability due to its low water solubility, which limits its veterinary clinical applications. As a non-polymeric drug carrier, γ-cyclodextrin was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35950734f7ef5bfccba83948bdcefaa8
https://doi.org/10.1016/j.ejpb.2022.10.024
https://doi.org/10.1016/j.ejpb.2022.10.024