Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Yilei, Zhang"'
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Limited supply of certain nutrients and deregulation of nucleus pulposus (NP) plays a key role in the pathogenesis of intervertebral disc degeneration (IVDD). However, whether nutrient deprivation-induced cell death, particularly
Externí odkaz:
https://doaj.org/article/2e86340dbb0249e593e71b932bb9dbb4
Autor:
Jin Wang, Minglin Wang, Shaobo Wu, Yanan Zhu, Kexin Fan, Yuhan Chen, Zhengtao Xiao, Jing Chen, Kangsheng Tu, Dongsheng Huang, Yilei Zhang, Qiuran Xu
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-11 (2024)
Abstract BAP1, BRCA1-Associated Protein 1, serves as a novel tumor suppressor through the deubiquitination of monoubiquitination of H2A and subsequent gene transcriptional regulation. Regulated cell death like apoptosis or ferroptosis is considered a
Externí odkaz:
https://doaj.org/article/5bf0559bd36e4f91963b65f9f14edbc5
Autor:
Zhan Liu, Kexin Fan, Aikedaimu Abudukeremu, Min Gao, Xinyue Tan, Xiaojuan Mao, Xinyu Li, Wenting Ma, Xusheng Ma, Caolong Li, Yinglai Yang, Kangsheng Tu, Jing Chen, Yilei Zhang, Yaqun Guan
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract LIMA1 is a LIM domain and Actin binding 1 protein that acts as a skeleton protein to promote cholesterol absorption, which makes it an ideal target for interfering with lipid metabolism. However, the detailed regulation of LIMA1 remains uncl
Externí odkaz:
https://doaj.org/article/5720a4e9218945a0a86eff0bb7a43dd0
Autor:
Shixiong Sun, Shilin Luo, Jie Chen, Ou Zhang, Qiongying Wu, Nianju Zeng, Jinlian Bi, Chunbing Zheng, Tenglong Yan, Zhiyuan Li, Jindong Chen, Yilei Zhang, Bing Lang
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionAutism spectrum disorders (ASD) are a set of heterogeneous neurodevelopmental disorders characterized by impaired social interactions and stereotypic behaviors. Current clinical care is palliative at the most and there remains huge unmet
Externí odkaz:
https://doaj.org/article/acaa3b06692b45fe950305f802098acf
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveTo assess the effectiveness and tolerability of both PD-1 and PD-L1 inhibitors in advanced cervical cancer (CC), focusing on varying PD-L1 levels.MethodsA comprehensive exploration was carried out on EMBASE, PubMed, Cochrane Library database
Externí odkaz:
https://doaj.org/article/7d5fe4a45db04564a6f81d79662069fe
Autor:
Shanshan Chen, Chunying Fan, Zijian Xu, Mengyao Pei, Jiemin Wang, Jiye Zhang, Yilei Zhang, Jiyu Li, Junliang Lu, Cheng Peng, Xiaofeng Wei
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract We disclose herein a strategy for the rapid synthesis of versatile organoselenium compounds under mild conditions. In this work, magnesium-based selenium nucleophiles are formed in situ from easily available organic halides, magnesium metal,
Externí odkaz:
https://doaj.org/article/f13ebc4f6cfe4db7ba6c7d3ea885c919
Autor:
Rundong Chen, Hanchen Liu, Guanghao Zhang, Qian Zhang, Weilong Hua, Lei Zhang, Nan Lv, Yilei Zhang, Dongwei Dai, Rui Zhao, Qiang Li, Qinghai Huang, Yi Xu, Pengfei Yang, Jianmin Liu, Qiao Zuo
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-12 (2024)
Abstract Background Stroke is the second leading cause of death worldwide, and observational studies have suggested a correlation between antioxidants and reduced stroke risk. However, it remains unclear whether causal relationships exist. Methods Th
Externí odkaz:
https://doaj.org/article/2f69255f920d4b389fe8b34393e1e863
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
As one lethal malignancy in women’s reproductive systems, ovarian cancer (OC) is frequently detected at an advanced phase during diagnosis. when the disease has spread widely. The absence of obvious symptoms and powerful screening tools in the earl
Externí odkaz:
https://doaj.org/article/88da4e9f92fe4dff96e85c2bdbcc0478
Publikováno v:
Zhenduanxue lilun yu shijian, Vol 22, Iss 06, Pp 567-572 (2023)
Objective: To investigate the value and significance of 18F-prostate-specific membrane antigen (18F-PSMA)-1007 PET/MR for early diagnosis of recurrence and metastasis in prostate cancer patients after radical prostatectomy (RP). Methods: A total of 1
Externí odkaz:
https://doaj.org/article/e6293bd238814fdfbf734af7a8c0cbad
Publikováno v:
Smart Cities, Vol 6, Iss 5, Pp 2347-2366 (2023)
The transport of freight involves numerous intermediate steps, such as freight consolidation, truck allocation, and routing, all of which exhibit high day-to-day variability. On the delivery side, drivers usually cover specific geographic regions, al
Externí odkaz:
https://doaj.org/article/884ab1d3e7fb45ae95a4f71f7ac39eed