Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Yikang S. Rong"'
Publikováno v:
Fly, Vol 12, Iss 1, Pp 41-45 (2018)
Telomere protects the ends of linear chromosomes. Telomere dysfunction fuels genome instability that can lead to diseases such as cancer. For over 30 years, Drosophila has fascinated the field as the only major model organism that does not rely on th
Externí odkaz:
https://doaj.org/article/89e56e3d6efb411e82651fbf983a54a6
A Single Residue Mutation in the Gαq Subunit of the G Protein Complex Causes Blindness in Drosophila
Autor:
Jinguo Cao, Murali K. Bollepalli, Yuhui Hu, Jin Zhang, Qiang Li, Hongmei Li, Hua Chang, Feng Xiao, Roger C. Hardie, Yikang S. Rong, Wen Hu
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 363-371 (2018)
Heterotrimeric G proteins play central roles in many signaling pathways, including the phototransduction cascade in animals. However, the degree of involvement of the G protein subunit Gαq is not clear since animals with previously reported strong l
Externí odkaz:
https://doaj.org/article/5e1c027e9e414dabbde1af7bf92904f3
Autor:
Pingsu Mao, Jingfan Liu, Zepeng Zhang, Hong Zhang, Haiying Liu, Song Gao, Yikang S. Rong, Yong Zhao
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Telomeres protect the ends of chromosomes from the DNA damage recognition machinery, however how damage in telomeres is repaired is poorly understood. Here the authors use CRISPR-Cas9 to induce DNA breaks and identify proliferation dependent homologo
Externí odkaz:
https://doaj.org/article/d2bac6d7cd1a4e06a3fb1dee8eae9893
Autor:
Maria Laura Di Giorgio, Patrizia Morciano, Elisabetta Bucciarelli, Antonella Porrazzo, Francesca Cipressa, Sara Saraniero, Diana Manzi, Yikang S. Rong, Giovanni Cenci
Publikováno v:
Cells, Vol 9, Iss 1, p 206 (2020)
The Drosophila melanogaster DmATPCL gene encodes for the human ATP Citrate Lyase (ACL) ortholog, a metabolic enzyme that from citrate generates glucose-derived Acetyl-CoA, which fuels central biochemical reactions such as the synthesis of fatty acids
Externí odkaz:
https://doaj.org/article/ae759777ef7d4722b470452473639d6f
Publikováno v:
G3 Genes|Genomes|Genetics. 12
Epithelia exposed to elements of the environment are protected by a mucus barrier in mammals. This barrier also serves to lubricate during organ movements and to mediate substance exchanges between the environmental milieu and internal organs. A majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e17fe80fa29b647d14a1dec729caf7e
https://doi.org/10.1093/g3journal/jkac126
https://doi.org/10.1093/g3journal/jkac126
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006435 (2016)
Multiple complexes protect telomeres. In telomerase-maintained organisms, Shelterin related complexes occupy the duplex region while the CST and Tpp1-Pot1 complexes bind the single stranded overhang of telomeres. Drosophila uses a transposon-based me
Externí odkaz:
https://doaj.org/article/fcf9bc8e86d14b939cb4cdb112cc3a11
Autor:
Tao Chen, Xiaolu Wei, Cécile Courret, Min Cui, Lin Cheng, Jing Wu, Kami Ahmad, Amanda M. Larracuente, Yikang S. Rong
Publikováno v:
PLOS Genetics. 18:e1010351
Advances in genomic technology led to a more focused pattern for the distribution of chromosomal proteins and a better understanding of their functions. The recent development of the CUT&RUN technique marks one of the important such advances. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b136df7797aab35b8d8637db56ed611
https://doi.org/10.1371/journal.pgen.1010351
https://doi.org/10.1371/journal.pgen.1010351
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 9 (2021)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
DNA topoisomerase I (Top1) maintains chromatin conformation during transcription. While Top1 is not essential in simple eukaryotic organisms such as yeast, it is required for the development of multicellular organisms. In fact, tissue and cell-type-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d89170db82088f88fe8dce84f3bfae
https://doi.org/10.1093/g3journal/jkab202
https://doi.org/10.1093/g3journal/jkab202
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009098 (2020)
PLoS Genetics
PLoS Genetics
The 2,2,7-trimethylguanosine (TMG) cap is one of the first identified modifications on eukaryotic RNAs. TMG, synthesized by the conserved Tgs1 enzyme, is abundantly present on snRNAs essential for pre-mRNA splicing. Results from ex vivo experiments i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3806e6dd1a5683e19001d372e9560e15
https://doaj.org/article/22ed57e4891c4604bd0f2cf5b597a6ff
https://doaj.org/article/22ed57e4891c4604bd0f2cf5b597a6ff
Autor:
Giovanni Cenci, Sara Saraniero, Antonella Porrazzo, Francesca Cipressa, Maria Laura Di Giorgio, Patrizia Morciano, Yikang S. Rong, Diana Manzi, Elisabetta Bucciarelli
Publikováno v:
Cells, Vol 9, Iss 1, p 206 (2020)
The Drosophila melanogaster DmATPCL gene encodes for the human ATP Citrate Lyase (ACL) ortholog, a metabolic enzyme that from citrate generates glucose-derived Acetyl-CoA, which fuels central biochemical reactions such as the synthesis of fatty acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6bc785e42116c7d80bab784de0ef45
https://www.mdpi.com/2073-4409/9/1/206
https://www.mdpi.com/2073-4409/9/1/206