Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yikai Shou"'
Autor:
Xiaoxue Dong, Liqi Shu, Jinyu Zhang, Xu Yang, Xuejun Cheng, Xingsen Zhao, Wenzheng Qu, Qiang Zhu, Yikai Shou, Guoping Peng, Binggui Sun, Wen Yi, Qiang Shu, Xuekun Li
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-27 (2023)
Abstract Previous studies have shown that Ogt-mediated O-GlcNAcylation is essential for neuronal development and function. However, the function of O-GlcNAc transferase (Ogt) and O-GlcNAcylation in astrocytes remains largely unknown. Here we show tha
Externí odkaz:
https://doaj.org/article/cff9bbf32161460396f938618c10ac86
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
BackgroundCryptococcus neoformans is an opportunistic pathogen, which is more common in patients with AIDS. Increased intracranial pressure (ICP) is an important complication of cryptococcal meningitis (CM) and affects the therapeutic effect of CM.Ob
Externí odkaz:
https://doaj.org/article/e2129b5dca0a4b5b8e91926a20e8efb2
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 224, Iss , Pp 112678- (2021)
PM2.5 exposure is considered harmful to central nerve system, while the specific biochemical mechanism underlying is still unrevealed. Neuronal apoptosis is believed the crucial event in pathogenesis of neurodegenerative diseases, but evidence suppor
Externí odkaz:
https://doaj.org/article/e88ba360a17744d0804023c823340c82
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Brain organoids are derived from induced pluripotent stem cells and embryonic stem cells under three-dimensional culture condition. The generation of an organoid requires the self-assembly of stem cells, progenitor cells, and multiple types of differ
Externí odkaz:
https://doaj.org/article/101138bb7f6a4555ba05431da50f4041
Autor:
Huanhuan Wang, Wenhai Huang, Meihao Liang, Yingying Shi, Chixiao Zhang, Qin Li, Meng Liu, Yikai Shou, Hongping Yin, Xiaozheng Zhu, Xiaoyan Sun, Yu Hu, Zhengrong Shen
Publikováno v:
Cell & Bioscience, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Background Microglia activation is a crucial event in neurodegenerative disease. The depression of microglial inflammatory response is considered a promising therapeutic strategy. NFκB signaling, including IKK/IκB phosphotylation, p65 nuce
Externí odkaz:
https://doaj.org/article/56b6a22ad30d449b928608b72c980f9f
Publikováno v:
CNSneurological disorders drug targets.
Background: Alzheimer's disease (AD) is one of the most common irreversible degenerative diseases of the central nervous system. Recent studies have found that patients with AD generally experienced abnormal glucose metabolism. Xylitol is a functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29168a4dd3e2a214c5147c9400eccda5
https://pubmed.ncbi.nlm.nih.gov/36154609
https://pubmed.ncbi.nlm.nih.gov/36154609
Autor:
Yingying Shi, Hongping Yin, Minyan Chen, Linjie Lu, Dongjiu Zhao, Xiaozheng Zhu, Qiwei Qian, Danna Zhu, Yikai Shou, Yu Hu, Huanhuan Wang
Publikováno v:
Toxicology Letters. 331:208-217
Fine particulate matter 2.5 (PM2.5), one of the main components of air pollutants, seriously threatens human health. Possible neuronal dysfunction induced by PM2.5 has received extensive attention. However, there is little evidence for the specific b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb34cf1d4c6abbfaed489cbc7ec4b03
https://doi.org/10.1016/j.toxlet.2020.06.014
https://doi.org/10.1016/j.toxlet.2020.06.014
Publikováno v:
Toxicology Letters. 329:31-37
PM2.5 particles are widely believed to be associated with respiratory and cardiovascular diseases. However, recent studies have reported that PM2.5 may be associated with neurodegenerative diseases. The exact mechanism by which PM2.5 mediates neuroto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a9235ab68134d5f383c5b9e934a51f
https://doi.org/10.1016/j.toxlet.2020.04.017
https://doi.org/10.1016/j.toxlet.2020.04.017
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 224, Iss, Pp 112678-(2021)
PM2.5 exposure is considered harmful to central nerve system, while the specific biochemical mechanism underlying is still unrevealed. Neuronal apoptosis is believed the crucial event in pathogenesis of neurodegenerative diseases, but evidence suppor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f8f2de741bfe3ec3fdecaf99fd5a42
http://www.sciencedirect.com/science/article/pii/S0147651321007909
http://www.sciencedirect.com/science/article/pii/S0147651321007909
Autor:
Weize Xu, Xuekun Li, Yikai Shou, Yuhang Cao, Yingliang Zhuang, Qiang Shu, Xiaoli Huang, Junchen Chen
Publikováno v:
Human Molecular Genetics. 29:727-735
N 6-methyladenosine (m6A) modification of RNA is deposited by the methyltransferase complex consisting of Mettl3 and Mettl14 and erased by demethylase Fto and Alkbh5 and is involved in diverse biological processes. However, it remains largely unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21803b851036986238200c3e164aa069
https://doi.org/10.1093/hmg/ddz274
https://doi.org/10.1093/hmg/ddz274