Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yik Y. L. Yu"'
Autor:
Marielle C Gold, Stefania Cerri, Susan Smyk-Pearson, Meghan E Cansler, Todd M Vogt, Jacob Delepine, Ervina Winata, Gwendolyn M Swarbrick, Wei-Jen Chua, Yik Y L Yu, Olivier Lantz, Matthew S Cook, Megan D Null, David B Jacoby, Melanie J Harriff, Deborah A Lewinsohn, Ted H Hansen, David M Lewinsohn
Publikováno v:
PLoS Biology, Vol 8, Iss 6, p e1000407 (2010)
Control of infection with Mycobacterium tuberculosis (Mtb) requires Th1-type immunity, of which CD8+ T cells play a unique role. High frequency Mtb-reactive CD8+ T cells are present in both Mtb-infected and uninfected humans. We show by limiting dilu
Externí odkaz:
https://doaj.org/article/d438072d9b3a4f378beabc48f892f372
Autor:
James E. McLaren, Kristin Ladell, Gwendolyn Swarbrick, David Price, Joseph A. Reistetter, Ted H. Hansen, Ole Lund, Deborah A. Lewinsohn, Morten Nielsen, David M. Lewinsohn, Yik Y. L. Yu, Marielle C. Gold, Sue Smyk-Pearson
Publikováno v:
Molecular Immunology. 68:133-167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7f2d33da27a003a0ef58fcdbda2547
https://doi.org/10.1016/j.molimm.2014.04.002
https://doi.org/10.1016/j.molimm.2014.04.002
Autor:
Changwon Park, Inyoung Kang, Ting Wang, Kyunghee Choi, Fang Liu, Dennis K. Watson, Ju Young Kim, Min‐Ji Cha, Yik Y. L. Yu, Daofeng Li
Publikováno v:
EMBO reports. 16:654-669
The ETS factor ETV2 (aka ER71) is essential for the generation of the blood and vascular system, as ETV2 deficiency leads to a complete block in blood and endothelial cell formation and embryonic lethality in the mouse. However, the ETV2-mediated gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2748907738180b63feb283a94df694af
https://doi.org/10.15252/embr.201439939
https://doi.org/10.15252/embr.201439939
Autor:
Paul F. Robbins, Zhili Zheng, Steven A. Rosenberg, John R. Wunderlich, Morvarid Moayeri, Michael S. Hughes, Mark E. Dudley, Yong Li, Richard A. Morgan, Robert G. Hawley, Yik Y. L. Yu
Publikováno v:
Human Gene Therapy. 16:457-472
The genes for the alpha and beta chains of a highly reactive anti-MART-1 T-cell receptor were isolated from T-lymphocytes that mediated in vivo regression of tumor in a patient with metastatic melanoma. These genes were cloned and inserted into MSCV-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd5217c73a95f8e0c4a7fb1636108f8
https://doi.org/10.1089/hum.2005.16.457
https://doi.org/10.1089/hum.2005.16.457
Autor:
Mark E. Dudley, Zhili Zheng, Steven A. Rosenberg, Nicholas P. Restifo, John R. Wunderlich, Paul F. Robbins, Richard A. Morgan, Marc R. Theoret, Michael S. Hughes, Yik Y. L. Yu
Publikováno v:
The Journal of Immunology. 171:3287-3295
The α- and β-chains of the TCR from a highly avid anti-gp100 CTL clone were isolated and used to construct retroviral vectors that can mediate high efficiency gene transfer into primary human lymphocytes. Expression of this TCR gene was confirmed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4b593ab4be7350922e2d8cd4f6d549
https://doi.org/10.4049/jimmunol.171.6.3287
https://doi.org/10.4049/jimmunol.171.6.3287
Publikováno v:
The Journal of Immunology. 168:3145-3149
We report in this work the expression and characterization of class I molecules expressed as single-chain trimers consisting of an antigenic peptide-spacer-β2-microglobulin-spacer H chain. Our results indicate that these single-chain constructs asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b706c6949053ac87cc9b62a2999494
https://doi.org/10.4049/jimmunol.168.7.3145
https://doi.org/10.4049/jimmunol.168.7.3145
Publikováno v:
The Journal of Immunology. 166:6686-6692
Before peptide binding in the endoplasmic reticulum, the class I heavy (H) chain-β2-microglobulin complexes are detected in association with TAP and two chaperones, TPN and CRT. Recent studies have shown that the thiol-dependent reductase, ERp57, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e19a15ec01c86cc074799a8ee8ad8b
https://doi.org/10.4049/jimmunol.166.11.6686
https://doi.org/10.4049/jimmunol.166.11.6686
Autor:
Yik Y. L. Yu, Christine M. Hilbert, Ted H. Hansen, Nancy B. Myers, Michael R. Harris, Ganesaratnam K. Balendiran
Publikováno v:
International Immunology. 11:1897-1906
Nascent class I molecules have been hypothesized to undergo a conformational change when they bind peptide based on the observation that most available antibodies only detect peptide-loaded class I. Furthermore recent evidence suggests that this pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8189f86450b7ac5ca17d64cb67bc5fe1
https://doi.org/10.1093/intimm/11.12.1897
https://doi.org/10.1093/intimm/11.12.1897
Autor:
Yik Y. L. Yu, H¯eth R. Turnquist, Nancy B. Myers, Ganesaratnam K. Balendiran, Ted H. Hansen, Joyce C. Solheim
Publikováno v:
The Journal of Immunology. 163:4427-4433
Presentation of antigenic peptides to CTLs at the cell surface first requires assembly of MHC class I with peptide and β2-microglobulin in the endoplasmic reticulum. This process involves an assembly complex of several proteins, including TAP, tapas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e00f16f6d855e8e0396970ed240c5075
https://doi.org/10.4049/jimmunol.163.8.4427
https://doi.org/10.4049/jimmunol.163.8.4427
Publikováno v:
The Journal of Immunology. 160:5404-5409
Before peptide binding, a variety of endoplasmic reticulum (ER) proteins are associated with class I including calnexin, TAP, calreticulin, and tapasin. Although the selective functions of any one of these ER proteins have been difficult to define, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ae9cc6ceec5744b8b06ffa922d9b43
https://doi.org/10.4049/jimmunol.160.11.5404
https://doi.org/10.4049/jimmunol.160.11.5404