Terminal Alkyne-Modified DNA Aptamers with Enhanced Protein Binding Affinities.

Autor: Kohn EM; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Konovalov K; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.; Theoretical Chemistry Institute, Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Gomez CA; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Hoover GN; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Yik AK; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.; Theoretical Chemistry Institute, Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Huang X; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.; Theoretical Chemistry Institute, Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Martell JD; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.; Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2023 Sep 15; Vol. 18 (9), pp. 1976-1984. Date of Electronic Publication: 2023 Aug 02.