Zobrazeno 1 - 10
of 884
pro vyhledávání: '"Yijun Chen"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Exosomes play a crucial role in the progression and spread of pancreatic cancer, serving not only as promoters of tumor growth and organ-specific metastasis but also as promising biomarkers and targets for treatment. These nano vesicles enha
Externí odkaz:
https://doaj.org/article/01d55d8cfb0b4148871867ed5ea4b8db
Autor:
Yanzi Sun, Yishu Wang, Chunyan Liu, Yingshuang Huang, Qiulin Long, Caoyun Ju, Can Zhang, Yijun Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Tyrosine kinase inhibitors have been the standard treatment for patients with Philadelphia chromosome-positive (Ph+) leukemia. However, a series of issues, including drug resistance, relapse and intolerance, are still an unmet medical need.
Externí odkaz:
https://doaj.org/article/ab03536952134cfcbd34ade302bbd69c
Autor:
Xuemei Zeng, Yijun Chen, Anuradha Sehrawat, Jihui Lee, Tara K. Lafferty, Julia Kofler, Sarah B. Berman, Robert A. Sweet, Dana L. Tudorascu, William E. Klunk, Milos D. Ikonomovic, Anna Pfister, Henrik Zetterberg, Beth E. Snitz, Anne D. Cohen, Victor L. Villemagne, Tharick A. Pascoal, M. llyas Kamboh, Oscar I. Lopez, Kaj Blennow, Thomas K. Karikari
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-22 (2024)
Abstract Alzheimer’s disease (AD), the most common form of dementia, remains challenging to understand and treat despite decades of research and clinical investigation. This might be partly due to a lack of widely available and cost-effective modal
Externí odkaz:
https://doaj.org/article/64c9dbe829a54f7ea0148397b7f5ae86
Autor:
Yan Wang, Yijun Chen, Junpeng Gao, Haoling Xie, Yuqing Guo, Jingwei Yang, Jun’e Liu, Zonggui Chen, Qingqing Li, Mengyao Li, Jie Ren, Lu Wen, Fuchou Tang
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-22 (2024)
Abstract Single-cell whole-genome sequencing methods have undergone great improvements over the past decade. However, allele dropout, which means the inability to detect both alleles simultaneously in an individual diploid cell, largely restricts the
Externí odkaz:
https://doaj.org/article/863cc5ee8c764e3b8137dd097ef7eb65
Autor:
Edward H. Livingston, MD, FACS, AGAF, Hila Zelicha, RD, PhD, Erik P. Dutson, MD, Zhaoping Li, MD, PhD, Matthew L. Maciejewski, PhD, Yijun Chen, MD
Publikováno v:
Annals of Surgery Open, Vol 5, Iss 2, p e414 (2024)
Objective:. To assess the external validity of randomized controlled trials (RCTs) of bariatric surgical treatment on diabetes control. Background:. Multisite RCTs provide the strongest evidence supporting clinical treatments and have the greatest in
Externí odkaz:
https://doaj.org/article/111e3e7f07a34740aa5b887c46bb5b8b
Autor:
Mengya Zhao, Beiying Dai, Xiaodong Li, Yixin Zhang, Chun Qiao, Yaru Qin, Zhao Li, Qingmei Li, Shuzhen Wang, Yong Yang, Yijun Chen
Publikováno v:
eLife, Vol 12 (2024)
Philadelphia chromosome-positive (Ph+) leukemia is a fatal hematological malignancy. Although standard treatments with tyrosine kinase inhibitors (TKIs) have achieved remarkable success in prolonging patient survival, intolerance, relapse, and TKI re
Externí odkaz:
https://doaj.org/article/e37ea5e03f2b4c1590e63e874d6ee52f
Publikováno v:
Mathematical Biosciences and Engineering, Vol 21, Iss 2, Pp 2787-2812 (2024)
In response to the problem of coverage redundancy and coverage holes caused by the random deployment of nodes in wireless sensor networks (WSN), a WSN coverage optimization method called GARWOA is proposed, which combines the genetic algorithm (GA) a
Externí odkaz:
https://doaj.org/article/814addf52e7a4f2f8cbcb314b8a09634
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract To explore the mechanism of the end-to-end transmission delay of the communication network on the collaborative driving process for traffic flow in the vehicle-to-vehicle communication environment, based on the idea of the car-following mode
Externí odkaz:
https://doaj.org/article/a756830e11a34282be831be7c33d9bf9
Autor:
Jiayu Hu, Yijun Chen
Publikováno v:
Bioresources and Bioprocessing, Vol 10, Iss 1, Pp 1-10 (2023)
Abstract Background The accumulation of fast-growing polyethylene terephthalate (PET) wastes has posed numerous threats to the environments and human health. Enzymatic degradation of PET is a promising approach for PET waste treatment. Currently, the
Externí odkaz:
https://doaj.org/article/5fdff8c88bb94bcab34d5d561da3ca03
Autor:
Yijun Chen, Fengyu Zhang, Bolin Zhang, Bogusz Trojanowicz, Monika Hämmerle, Jörg Kleeff, Yoshiaki Sunami
Publikováno v:
Cancer Reports, Vol 7, Iss 2, Pp n/a-n/a (2024)
Abstract Background Pancreatic cancer is one of the most aggressive human malignancies. Previous research has shown that periostin (POSTN) promotes pancreatic cancer cell proliferation, migration, and invasion. Further, POSTN is involved in tumor mic
Externí odkaz:
https://doaj.org/article/83c6cda3760144b5987c4eed8cf60852