Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yijian Yan"'
Autor:
Helena Aspernig, Thomas Heimbucher, Wenjing Qi, Dipak Gangurde, Sedric Curic, Yijian Yan, Erika Donner von Gromoff, Ralf Baumeister, Antje Thien
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1399-1409.e5 (2019)
Summary: Autophagy is stimulated by stress conditions and needs to be precisely tuned to ensure cellular homeostasis and organismal development and health. The kinase mechanistic target of rapamycin (mTOR) forms the enzymatic core of the highly conse
Externí odkaz:
https://doaj.org/article/d9f62352f8184565836af18d7e421512
Autor:
Wenjing Qi, Yijian Yan, Dietmar Pfeifer, Erika Donner V Gromoff, Yimin Wang, Wolfgang Maier, Ralf Baumeister
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006801 (2017)
Activation of the FOXO transcription factor DAF-16 by reduced insulin/IGF signaling (IIS) is considered to be beneficial in C. elegans due to its ability to extend lifespan and to enhance stress resistance. In the germline, cell-autonomous DAF-16 act
Externí odkaz:
https://doaj.org/article/0598276aa50b46e68fb5172b18d8bedf
Autor:
Weiping Zou, Jing-Yuan Fang, Ilona Kryczek, Haoyan Chen, Grzegorz Wallner, Marek Majewski, Witold Zgodziński, Linda Vatan, Sara Grove, Shuang Wei, Gaopeng Li, Yijian Yan, Peng Liao, Weimin Wang, Jiajia Zhou, Weichao Wang, Shasha Li, Jian Zhang, Xiong Li, Fang Hua, Wan Du
Supplementary Figure S1-9 and Supplementary Tables S1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92274e513c323e5adda02a029a22aa46
https://doi.org/10.1158/2159-8290.22540280.v1
https://doi.org/10.1158/2159-8290.22540280.v1
Autor:
Weiping Zou, Jing-Yuan Fang, Ilona Kryczek, Haoyan Chen, Grzegorz Wallner, Marek Majewski, Witold Zgodziński, Linda Vatan, Sara Grove, Shuang Wei, Gaopeng Li, Yijian Yan, Peng Liao, Weimin Wang, Jiajia Zhou, Weichao Wang, Shasha Li, Jian Zhang, Xiong Li, Fang Hua, Wan Du
Mutations in IFN and MHC signaling genes endow immunotherapy resistance. Patients with colorectal cancer infrequently exhibit IFN and MHC signaling gene mutations and are generally resistant to immunotherapy. In exploring the integrity of IFN and MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e53f27c74333b3e50384590815ff6de
https://doi.org/10.1158/2159-8290.c.6549344.v1
https://doi.org/10.1158/2159-8290.c.6549344.v1
Autor:
Wilson KC. Leung, Suk-yu Yau, Yijian Yang, Anthony WL. Kwok, Eliza ML. Wong, Jasmine KM. Cheung, Edward WC. Shum, Simon C. Lam, Lorna KP. Suen
Publikováno v:
Journal of Exercise Science & Fitness, Vol 22, Iss 4, Pp 278-287 (2024)
Background: /Objective. An explosion in global obesity epidemic poses threats to the healthcare system by provoking risks of many debilitating diseases, including cognitive dysfunction. Physical activity has been shown to alleviate the deleterious ef
Externí odkaz:
https://doaj.org/article/cfa10527679a4c559b0649df83990ec8
Autor:
Linda Vatan, Weichao Wang, Angelo Aguilar, Shasha Li, Sara Grove, Xueting Lang, Shaomeng Wang, Jing Li, Ilona Kryczek, Peng Liao, Jiajia Zhou, Yijian Yan, Weimin Wang, Wan Du, Shuang Wei, Gaopeng Li, Weiping Zou, Xiong Li, Jiali Yu, Heng Lin
Publikováno v:
Nature immunology
Targeting the p53-MDM2 pathway to reactivate tumor p53 is a chemotherapeutic approach. However, the involvement of this pathway in CD8+ T cell-mediated antitumor immunity is unknown. Here, we report that mice with MDM2 deficiency in T cells exhibit a
Autor:
Linda Vatan, Weiping Zou, Yijian Yan, Weichao Wang, Gaopeng Li, Xiong Li, Jiajia Zhou, Shuang Wei, Grzegorz Wallner, Weimin Wang, Marek Majewski, Wan Du, Jian Zhang, Shasha Li, Sara Grove, Haoyan Chen, Fang Hua, Witold Zgodziński, Jing-Yuan Fang, Peng Liao, Ilona Kryczek
Publikováno v:
Cancer Discovery. 11:1826-1843
Mutations in IFN and MHC signaling genes endow immunotherapy resistance. Patients with colorectal cancer infrequently exhibit IFN and MHC signaling gene mutations and are generally resistant to immunotherapy. In exploring the integrity of IFN and MHC
Publikováno v:
Journal of Exercise Science & Fitness, Vol 22, Iss 3, Pp 237-244 (2024)
Background/objective: Previous studies have indicated that mind-body exercises can reduce pain and improve function for patients with musculoskeletal conditions. Yi Jin Bang is a novel home-based Chinese mind-body Qigong exercise for shoulder pain. H
Externí odkaz:
https://doaj.org/article/61e8ba2ad8b343a19bf9b3aa71b25ca2
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract This study aims to enhance the safety and efficiency of port navigation by reducing ship collision accidents, minimizing environmental risks, and optimizing waterways to increase port throughput. Initially, a three-dimensional map of the por
Externí odkaz:
https://doaj.org/article/1af4cda581cd4263acfed515f7af7edb
Publikováno v:
Frontiers in Sports and Active Living, Vol 6 (2024)
The ageing population creates concerns and challenges worldwide. The large number of older adults (aged over 65) in Hong Kong continues to rise as people live longer. This may result in heavy burdens on public services and problems such as a shortage
Externí odkaz:
https://doaj.org/article/1be22ba37a034f6d8ec6c4a0f6922fe6