Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Yiing Lin"'
Autor:
Yashvardhan Jain, Leah L. Godwin, Yingnan Ju, Naveksha Sood, Ellen M. Quardokus, Andreas Bueckle, Teri Longacre, Aaron Horning, Yiing Lin, Edward D. Esplin, John W. Hickey, Michael P. Snyder, Nathan Heath Patterson, Jeffrey M. Spraggins, Katy Börner
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract The Human BioMolecular Atlas Program (HuBMAP) aims to compile a Human Reference Atlas (HRA) for the healthy adult body at the cellular level. Functional tissue units (FTUs), relevant for HRA construction, are of pathobiological significance.
Externí odkaz:
https://doaj.org/article/a82090e71a744dd18fb9cc682a3d9c64
Autor:
Kelsy C. Cotto, Yang-Yang Feng, Avinash Ramu, Megan Richters, Sharon L. Freshour, Zachary L. Skidmore, Huiming Xia, Joshua F. McMichael, Jason Kunisaki, Katie M. Campbell, Timothy Hung-Po Chen, Emily B. Rozycki, Douglas Adkins, Siddhartha Devarakonda, Sumithra Sankararaman, Yiing Lin, William C. Chapman, Christopher A. Maher, Vivek Arora, Gavin P. Dunn, Ravindra Uppaluri, Ramaswamy Govindan, Obi L. Griffith, Malachi Griffith
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Analysing the regulatory consequences of mutations and splice variants at large scale in cancer requires efficient computational tools. Here, the authors develop RegTools, a software package that can identify splice-associated variants from large-sca
Externí odkaz:
https://doaj.org/article/a791b7f280e84d3d8c3cf984f3f564cd
Publikováno v:
Cells, Vol 11, Iss 24, p 4083 (2022)
Mitochondrial autophagy (mitophagy) is a central catabolic event for mitochondrial quality control. Defective or insufficient mitophagy, thus, can result in mitochondrial dysfunction, and ultimately cell death. There is a strong causal relationship b
Externí odkaz:
https://doaj.org/article/a9881fb988e64c60acc19fe4bcde1690
Autor:
Min Xu, MD, Fangyu Zhou, MD, Ola Ahmed, MD, Lucy V. Randle, BSc, Jun-Kyu Shin, PhD, Yuehui Zhu, PhD, Gundumi A. Upadhya, PhD, Kathleen Byrnes, MD, Brian Wong, PhD, Jae-Sung Kim, PhD, Yiing Lin, MD, PhD, William C. Chapman, MD
Publikováno v:
Transplantation Direct, Vol 7, Iss 12, p e789 (2021)
Background. Perfusate lactate clearance (LC) is considered one of the useful indicators of liver viability assessment during normothermic machine perfusion (NMP); however, the applicable scope and potential mechanisms of LC remain poorly defined in t
Externí odkaz:
https://doaj.org/article/a3a0dad254144335b8d47cdb3a5273e8
Autor:
Margaret Nalugo, John Cashin, Xiaohua Jin, Jeffrey Millman, Maria Remedi, Connor Engel, Dillon Williams, Yiing Lin, Mohamed A. Zayed
Publikováno v:
JVS - Vascular Science, Vol 2, Iss , Pp 283- (2021)
Externí odkaz:
https://doaj.org/article/ebcb4e4ae0a04bcea7902d1573ebf411
Autor:
Chandu Vemuri, MD, Gundumi A. Upadhya, MD, Batool Arif, MD, Jianluo Jia, MD, Yiing Lin, MD, PhD, Joseph P. Gaut, MD, PhD, Jawad Fazal, MD, Hua Pan, MD, Samuel A. Wickline, MD, William C. Chapman, MD
Publikováno v:
Transplantation Direct, Vol 4, Iss 9, p e384 (2018)
Background. Over 100 000 patients await renal transplantation and 4000 die per year. Compounding this mismatch between supply and demand is delayed graft function which contributes to short-term and long-term graft failures. Previously, we reported t
Externí odkaz:
https://doaj.org/article/7b6524d2001b4d9a8221f1a6d0698d1e
Autor:
Sabarinathan Ramachandran, Haseeb Ilias Basha, Nayan J Sarma, Yiing Lin, Jeffrey S Crippin, William C Chapman, Thalachallour Mohanakumar
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70744 (2013)
Hepatitis C virus (HCV) induced liver disease is the leading indication for liver transplantation (LTx). Reinfection and accelerated development of fibrosis is a universal phenomenon following LTx. The molecular events that lead to fibrosis following
Externí odkaz:
https://doaj.org/article/17595f9b068146aaa67e0647903bb4f2
Autor:
Zachary L Skidmore, Jason Kunisaki, Yiing Lin, Kelsy C Cotto, Erica K Barnell, Jasreet Hundal, Kilannin Krysiak, Vincent Magrini, Lee Trani, Jason R Walker, Robert Fulton, Elizabeth M Brunt, Christopher A Miller, Richard K Wilson, Elaine R Mardis, Malachi Griffith, William Chapman, Obi L Griffith
Publikováno v:
Cancer Genet
BackgroundLiver cancer is the second leading cause of cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) risk factors include chronic hepatitis, cirrhosis, and alcohol abuse, whereby tumorigenesis is induced through inflammation and subs
Autor:
Bradley S Kushner, Maria B Doyle, Adeel S Khan, Yiing Lin, Tarek Alhamad, Jennifer Yu, William C Chapman, Jason R Wellen
Publikováno v:
Journal of the American College of Surgeons.
Autor:
Cliona O'Farrelly, Brian W. Wong, Min Xu, Ola Ahmed, Yiing Lin, Alexander N Wein, Fangyu Zhou, William C. Chapman, Gundumi A. Upadhya, Li Ye
Publikováno v:
American Journal of Transplantation. 22:58-70
Antioxidant defence mechanisms, such as the nuclear factor-erythroid 2-related-factor-2 (NRF2) axis, are integral to oxidative stress responses and ischemic injury. Hepatic antioxidant capacity is contingent on parenchymal quality, and there is a nee