Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yih-Chih Chan"'
Autor:
Michael Y. He, Michael M. Halford, Ruofei Liu, James P. Roy, Zoe L. Grant, Leigh Coultas, Niko Thio, Omer Gilan, Yih-Chih Chan, Mark A. Dawson, Marc G. Achen, Steven A. Stacker
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Through three-dimensional CRISPR screening, He et al. report that functional inhibition of BET family of proteins BRD2/3/4 shows mitigating effects on blood endothelial cell (EC) survival and/or proliferation upon VEGFA blockade. An interaction betwe
Externí odkaz:
https://doaj.org/article/0a802170899b49c7b97c4550e22321e7
Autor:
Ashley P. Ng, Hannah D. Coughlan, Soroor Hediyeh-zadeh, Kira Behrens, Timothy M. Johanson, Michael Sze Yuan Low, Charles C. Bell, Omer Gilan, Yih-Chih Chan, Andrew J. Kueh, Thomas Boudier, Rebecca Feltham, Anna Gabrielyan, Ladina DiRago, Craig D. Hyland, Helen Ierino, Sandra Mifsud, Elizabeth Viney, Tracy Willson, Mark A. Dawson, Rhys S. Allan, Marco J. Herold, Kelly Rogers, David M. Tarlinton, Gordon K. Smyth, Melissa J. Davis, Stephen L. Nutt, Warren S. Alexander
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
B cell development is tightly regulated in a stepwise manner to ensure proper generation of repertoire diversity via somatic gene rearrangements. Here, the authors show that a transcription factor, Erg, functions at the earliest stage to critically c
Externí odkaz:
https://doaj.org/article/6cd266dc641c4e128ba4ff9c8fb14771
Autor:
Charles C. Bell, Katie A. Fennell, Yih-Chih Chan, Florian Rambow, Miriam M. Yeung, Dane Vassiliadis, Luis Lara, Paul Yeh, Luciano G. Martelotto, Aljosja Rogiers, Brandon E. Kremer, Olena Barbash, Helai P. Mohammad, Timothy M. Johanson, Marian L. Burr, Arindam Dhar, Natalie Karpinich, Luyi Tian, Dean S. Tyler, Laura MacPherson, Junwei Shi, Nathan Pinnawala, Chun Yew Fong, Anthony T. Papenfuss, Sean M. Grimmond, Sarah-Jane Dawson, Rhys S. Allan, Ryan G. Kruger, Christopher R. Vakoc, David L. Goode, Shalin H. Naik, Omer Gilan, Enid Y. N. Lam, Jean-Christophe Marine, Rab K. Prinjha, Mark A. Dawson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
There is increasing evidence that epigenetic mechanisms contribute to therapeutic resistance in cancer. Here the authors study AML patient samples and a mouse model of non-genetic resistance and find that transcriptional plasticity drives stable epig
Externí odkaz:
https://doaj.org/article/afef38c61db14a30844be963ce6499a0
Autor:
Paul Yeh, Tane Hunter, Devbarna Sinha, Sarah Ftouni, Elise Wallach, Damian Jiang, Yih-Chih Chan, Stephen Q. Wong, Maria Joao Silva, Ravikiran Vedururu, Kenneth Doig, Enid Lam, Gisela Mir Arnau, Timothy Semple, Meaghan Wall, Andjelija Zivanovic, Rishu Agarwal, Pasquale Petrone, Kate Jones, David Westerman, Piers Blombery, John F. Seymour, Anthony T. Papenfuss, Mark A. Dawson, Constantine S. Tam, Sarah-Jane Dawson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Disease monitoring of chronic lymphocytic leukaemia (CLL) is a challenge. Here, the authors show that serial ctDNA analysis in 32 CLL patients allows monitoring of clonal dynamics over time, and identifies the emergence of genomic changes associated
Externí odkaz:
https://doaj.org/article/a5d0115fb7e149b29d91aa033cf28281
Autor:
Mark A. Dawson, Raphaël Rodriguez, Kate McArthur, Andrew H. Wei, David C.S. Huang, Kristin K. Brown, Andrew G. Cox, Georg Ramm, Sarah-Jane Dawson, Estelle Duprez, Mathilde Poplineau, Giovanna Pomilio, Véronique Litalien, Marian L. Burr, Tatiana Cañeque, Enid Y.N. Lam, Brian Liddicoat, Laura MacPherson, Lorey Smith, Kevin Tran, Kah Lok Chan, James A. Kuzich, Caitlin L. Rowe, Ali Motazedian, Yih-Chih Chan, Fiona C. Brown, Sebastian Müller, Andrew A. Guirguis, Sylvain Garciaz
Cancer cell metabolism is increasingly recognized as providing an exciting therapeutic opportunity. However, a drug that directly couples targeting of a metabolic dependency with the induction of cell death in cancer cells has largely remained elusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9c0945d12fd02b9cd87bbec72de7cf
https://doi.org/10.1158/2159-8290.c.6549508
https://doi.org/10.1158/2159-8290.c.6549508
Autor:
Mark A. Dawson, Raphaël Rodriguez, Kate McArthur, Andrew H. Wei, David C.S. Huang, Kristin K. Brown, Andrew G. Cox, Georg Ramm, Sarah-Jane Dawson, Estelle Duprez, Mathilde Poplineau, Giovanna Pomilio, Véronique Litalien, Marian L. Burr, Tatiana Cañeque, Enid Y.N. Lam, Brian Liddicoat, Laura MacPherson, Lorey Smith, Kevin Tran, Kah Lok Chan, James A. Kuzich, Caitlin L. Rowe, Ali Motazedian, Yih-Chih Chan, Fiona C. Brown, Sebastian Müller, Andrew A. Guirguis, Sylvain Garciaz
Supplementary movie from Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebccd70f9946bd07385a5cfd666d4a4
https://doi.org/10.1158/2159-8290.22540921.v1
https://doi.org/10.1158/2159-8290.22540921.v1
Autor:
Mark A. Dawson, Raphaël Rodriguez, Kate McArthur, Andrew H. Wei, David C.S. Huang, Kristin K. Brown, Andrew G. Cox, Georg Ramm, Sarah-Jane Dawson, Estelle Duprez, Mathilde Poplineau, Giovanna Pomilio, Véronique Litalien, Marian L. Burr, Tatiana Cañeque, Enid Y.N. Lam, Brian Liddicoat, Laura MacPherson, Lorey Smith, Kevin Tran, Kah Lok Chan, James A. Kuzich, Caitlin L. Rowe, Ali Motazedian, Yih-Chih Chan, Fiona C. Brown, Sebastian Müller, Andrew A. Guirguis, Sylvain Garciaz
Supplementary table from Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a16971acb0d67e5a21c433aaaebdf37
https://doi.org/10.1158/2159-8290.22540918.v1
https://doi.org/10.1158/2159-8290.22540918.v1
Autor:
Mark A. Dawson, Raphaël Rodriguez, Kate McArthur, Andrew H. Wei, David C.S. Huang, Kristin K. Brown, Andrew G. Cox, Georg Ramm, Sarah-Jane Dawson, Estelle Duprez, Mathilde Poplineau, Giovanna Pomilio, Véronique Litalien, Marian L. Burr, Tatiana Cañeque, Enid Y.N. Lam, Brian Liddicoat, Laura MacPherson, Lorey Smith, Kevin Tran, Kah Lok Chan, James A. Kuzich, Caitlin L. Rowe, Ali Motazedian, Yih-Chih Chan, Fiona C. Brown, Sebastian Müller, Andrew A. Guirguis, Sylvain Garciaz
Supplementary Data from Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40f5e2a0785ec6d4a7ba51a073db0e5
https://doi.org/10.1158/2159-8290.22540948.v1
https://doi.org/10.1158/2159-8290.22540948.v1
Autor:
Mark A. Dawson, Raphaël Rodriguez, Kate McArthur, Andrew H. Wei, David C.S. Huang, Kristin K. Brown, Andrew G. Cox, Georg Ramm, Sarah-Jane Dawson, Estelle Duprez, Mathilde Poplineau, Giovanna Pomilio, Véronique Litalien, Marian L. Burr, Tatiana Cañeque, Enid Y.N. Lam, Brian Liddicoat, Laura MacPherson, Lorey Smith, Kevin Tran, Kah Lok Chan, James A. Kuzich, Caitlin L. Rowe, Ali Motazedian, Yih-Chih Chan, Fiona C. Brown, Sebastian Müller, Andrew A. Guirguis, Sylvain Garciaz
Supplementary Figure from Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d1d2acedf28d1cfcdf78ed4d0cbdc6
https://doi.org/10.1158/2159-8290.22540936.v1
https://doi.org/10.1158/2159-8290.22540936.v1
Autor:
Omer Gilan, Charles C. Bell, Laure Talarmain, Daniel Neville, Kathy Knezevic, Daniel Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y.N. Lam, Mark A. Dawson
SummaryThe regulation of all chromatin-templated processes involves the selective recruitment of chromatin factors to facilitate DNA repair, replication, and transcription. Chromatin immunoprecipitation (ChIP) is a critical experimental method used t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4f18d16ef49b50b9db448233021931b
https://doi.org/10.1101/2023.03.17.533231
https://doi.org/10.1101/2023.03.17.533231