Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yih Wan Tan"'
Autor:
Chiradip Chatterjee, Sundramurthy Kumar, Smarajit Chakraborty, Yih Wan Tan, Ka Yin Leung, J Sivaraman, Yu-Keung Mok
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19208 (2011)
BackgroundThe putative needle complex subunit AscF forms a ternary complex with the chaperones AscE and AscG in the type III secretion system of Aeromonas hydrophila so as to avoid premature assembly. Previously, we demonstrated that the C-terminal r
Externí odkaz:
https://doaj.org/article/680e146151a5443a853a01a62a8de0aa
Autor:
Chacko Jobichen, Mo Li, Gal Yerushalmi, Yih Wan Tan, Yu-Keung Mok, Ilan Rosenshine, Ka Yin Leung, J Sivaraman
Publikováno v:
PLoS Pathogens, Vol 3, Iss 5, p e69 (2007)
Enterohemorrhagic Escherichia coli (EHEC) is a common cause of severe hemorrhagic colitis. EHEC's virulence is dependent upon a type III secretion system (TTSS) encoded by 41 genes. These genes are organized in several operons clustered in the locus
Externí odkaz:
https://doaj.org/article/5c8452ac0b66480db6e1331587898a0f
Autor:
Hui Qi Ng, Shuang Liu, Yan Li, Jeffrey Hill, CongBao Kang, Perlyn Zekui Kwek, Yih Wan Tan, Joma Joy, Alvin W. Hung, Thomas H. Keller, Anna Ngo
Publikováno v:
Biomolecular NMR Assignments. 11:225-229
NSD3 is a histone H3 methyltransferase that plays an important role in chromatin biology. A construct containing the methyltransferase domain encompassing residues Q1049-K1299 of human NSD3 was obtained and biochemical activity was demonstrated using
Publikováno v:
Protein Science. 18:1724-1734
In the type III secretion system (T3SS) of Aeromonas hydrophila, AcrH acts as a chaperone for translocators AopB and AopD. AcrH forms a stable 1:1 monomeric complex with AopD, whereas the 1:1 AcrH-AopB complex exists mainly as a metastable oligomeric
Autor:
Ka Yin Leung, Chacko Jobichen, Karthik Ramesh, Yih Wan Tan, Siew Leong Chan, Yunhan Hong, Van Sang Nguyen, Kang Wei Tan, J. Sivaraman, Yu-Keung Mok, Yongming Yuan, Jayaraman Seetharaman
Publikováno v:
Structure (London, England : 1993). 23(11)
Type III secretion systems (T3SSs) are adopted by pathogenic bacteria for the transport of effector proteins into host cells through the translocon pore composed of major and minor translocator proteins. Both translocators require a dedicated chapero
Autor:
Alvin W. Hung, Weiguang Seetoh, Jeffrey Hill, Grace Lin, Qiu Ying Lau, Nur Huda Binte Ahmad, Guo-Ying Chen, C. S. Brian Chia, Siew Wen Then, Ying Lei Wong, Anders Poulsen, Hui Qi Ng, Yih Wan Tan, Thomas H. Keller, Fui Mee Ng, CongBao Kang
Publikováno v:
ChemPlusChem. 80(8)
Bacterial resistance to antibiotics remains a serious threat to global health. The gyrase B enzyme is a well-validated target for developing antibacterial drugs. Despite being an attractive target for antibiotic development, there are currently no gy
Autor:
Siew Leong Chan, Tomasz Osinski, Maksymilian Chruszcz, J. Sivaraman, Yu-Keung Mok, Lesa R. Offermann, Fook Tim Chew, Yih Wan Tan, Wladek Minor
a b s t r a c t Bla g 4 is a male cockroach specific protein and is one of the major allergens produced by Blattella ger- manica (German cockroach). This protein belongs to the lipocalin family that comprises a set of proteins that characteristically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9dadf46bbf902ade5cca7a8aa5ec523
https://europepmc.org/articles/PMC4097008/
https://europepmc.org/articles/PMC4097008/
Autor:
Asha Manikkoth Balakrishna, Yvonne Yih-Wan Tan, Kunchithapadam Swaminathan, Anand M. Saxena, Henry Yu-Keung Mok
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 62:1024-1026
The structure determination of PilS, a type IV pilin, by X-ray crystallography is reported. The recombinant protein from Salmonella typhi was overexpressed, purified and crystallized. The crystals belong to space group P2(1)2(1)2, with unit-cell para
Autor:
Yvonne Yih-Wan Tan, Manfred G. Schmidt, Citra Nurfarah Zaini Mattar, Cecilia Rosales, Amit C. Nathwani, Nuryanti Johana, Irene Gil-Farina, Jerry Kok Yen Chan, Mahesh Choolani, Lay-Geok Tan, Arijit Biswas, Jenny McKintosh
Publikováno v:
Molecular Therapy. 24:S119
A concerted effort is being made to determine a safe way to treat the fetus with severe monogenic diseases. While the majority of affected pregnancies are currently terminated, intrauterine gene therapy (IUGT) may become a viable future option in wel
Autor:
Tan Ching Ong, Yih Wan Tan, Yuen Sung Tiong, Yu-Keung Mok, Siew Leong Chan, Fook Tim Chew, J. Sivaraman, Le Yau Yit
Publikováno v:
The Journal of biological chemistry. 284(5)
Inhalant allergens from cockroaches are an important cause of asthma to millions of individuals worldwide. Here we report for the first time the structures of two major cockroach allergens, Bla g 4 and Per a 4, that adopt a typical lipocalin fold but