Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yih Tai Chen"'
Autor:
Jo Ann Janovick, Sonia Fargue, Louis Scampavia, Christopher J. Danpure, Yih-Tai Chen, David C. Smithson, Timothy P. Spicer, Franck Madoux, P. Michael Conn
Publikováno v:
ASSAY and Drug Development Technologies. 13:16-24
Primary hyperoxaluria is a severe disease for which the best current therapy is dialysis or organ transplantation. These are risky, inconvenient, and costly procedures. In some patients, pyridoxine treatment can delay the need for these surgical proc
Publikováno v:
SLAS Discovery. 9:557-568
Deciphering the effects of compounds on molecular events within living cells is becoming an increasingly important component of drug discovery. In a model application of the industrial drug discovery process, the authors profiled a panel of 22 compou
Publikováno v:
The Journal of Cell Biology
The E-cadherin/catenin complex regulates Ca++-dependent cell–cell adhesion and is localized to the basal-lateral membrane of polarized epithelial cells. Little is known about mechanisms of complex assembly or intracellular trafficking, or how these
Publikováno v:
American Journal of Physiology-Cell Physiology. 276:C404-C418
The role of E-cadherin, a calcium-dependent adhesion protein, in organizing and maintaining epithelial junctions was examined in detail by expressing a fusion protein (GP2-Cad1) composed of the extracellular domain of a nonadherent glycoprotein (GP2)
Publikováno v:
The Journal of Cell Biology
Cadherin-mediated adhesion initiates cell reorganization into tissues, but the mechanisms and dynamics of such adhesion are poorly understood. Using time-lapse imaging and photobleach recovery analyses of a fully functional E-cadherin/GFP fusion prot
Autor:
Didier A. Mandlebrot, W. James Nelson, Elizabeth A. Murphy, Yih-Tai Chen, Sunil K. Shaw, Michael B. Brenner, Christina M. Parker, Gary J. Russell, Jonathan M.G. Higgins
Publikováno v:
The Journal of Cell Biology
The cadherins are a family of homophilic adhesion molecules that play a vital role in the formation of cellular junctions and in tissue morphogenesis. Members of the integrin family are also involved in cell to cell adhesion, but bind heterophilicall
Autor:
Yih-Tai Chen, Manfred Schliwa
Publikováno v:
Cell Motility and the Cytoskeleton. 17:214-226
Microtubule dynamics has been studied extensively in vitro, but comparatively little information is available on the in vivo behavior of microtubules. Here we report on the assembly, disassembly, and sliding of microtubules in the giant freshwater am
Autor:
Yih-Tai Chen, Sandra S. Shasby, Anant Kamath, D. Michael Shasby, Dana R. Ries, Michael C. Winter
Publikováno v:
The American journal of physiology. 277(5)
We tested the hypothesis that histamine alters the focal apposition of endothelial cells by acting on sites of cadherin-mediated cell-cell adhesion. Focal apposition was measured as the impedance of a cell-covered electrode, which was partitioned int
Autor:
Lonnie Lybarger, Steven R. Kain, Gisele Green, Robert Chervenak, George H. Patterson, Te Tuan Yang, Yih Tai Chen, David W. Piston, Paul A. Kitts, Parisa Sinai
Publikováno v:
The Journal of biological chemistry. 273(14)
The green fluorescent protein (GFP) from the jellyfish Aequorea victoria is a versatile reporter protein for monitoring gene expression and protein localization in a variety of systems. Applications using GFP reporters have expanded greatly due to th
Autor:
Yih-Tai Chen, W. James Nelson
Publikováno v:
Analytical biochemistry. 242(2)