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Akademický článek

Orlistat and ezetimibe could differently alleviate the high-fat diet-induced obesity phenotype by modulating the gut microbiota

Autor: Jin Jin, Jiani Wang, Ruyue Cheng, Yan Ren, Zhonghua Miao, Yating Luo, Qingqing Zhou, Yigui Xue, Xi Shen, Fang He, Haoming Tian

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

This study aimed to evaluate the possible anti-obesity effects of orlistat and ezetimibe and determine the mechanism by which they alter the composition of gut microbiota and short-chain fatty acids (SCFAs) in mice with a high-fat diet (HFD)-induced

Externí odkaz: https://doaj.org/article/023d3b72747d4feea3a6f45288b155e1

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Akademický článek

Distinctive Gut Microbiota in Patients with Overweight and Obesity with Dyslipidemia and its Responses to Long-term Orlistat and Ezetimibe Intervention: A Randomized Controlled Open-label Trial

Autor: Jin Jin, Ruyue Cheng, Yan Ren, Xi Shen, Jiani Wang, Yigui Xue, Huimin Zhang, Xiuhua Jia, Tingting Li, Fang He, Haoming Tian

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

This study investigated the gut microbiota and short chain fatty acids (SCFAs) characteristics of subjects with obesity from Xinjiang in northwestern China, a region with a multiethnic culture and characteristic lifestyle, and to explore the potentia

Externí odkaz: https://doaj.org/article/236d631504fa4a5c934dbe6039954190

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Distinctive Gut Microbiota in Patients with Overweight and Obesity with Dyslipidemia and its Responses to Long-term Orlistat and Ezetimibe Intervention: A Randomized Controlled Open-label Trial

Autor: Huimin Zhang, Xiuhua Jia, Jin Jin, Ruyue Cheng, Fang He, Yan Ren, Yigui Xue, Haoming Tian, Xi Shen, Tingting Li, Jiani Wang

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6daaad02767696b5f7adb16d8957fec4
https://www.frontiersin.org/articles/10.3389/fphar.2021.732541/full

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miRNA-15a regulates the proliferation and apoptosis of papillary thyroid carcinoma via regulating AKT pathway

Autor: Haoming Tian, Li Luo, Jie Zhang, Siyao Wang, Yigui Xue, Jin Jin

Publikováno v: OncoTargets and Therapy. 12:6217-6226

Aim Aberrantly expressed microRNAs (miRNAs) are involved in many diseases including cancer. The expression of miR-15a was reported to be downregulated in papillary thyroid carcinoma (PTC) compared to control tissue. However, the mechanism underlying

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91cc936b6da9f7cf9991afa30ffd9c7e
https://doi.org/10.2147/ott.s213210

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