Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yifang Ping"'
Autor:
Qiuhong Zhu, Panpan Liang, Hao Meng, Fangzhen Li, Wei Miao, Cuiying Chu, Wei Wang, Dongxue Li, Cong Chen, Yu Shi, Xingjiang Yu, Yifang Ping, Chaoshi Niu, Hai-bo Wu, Aili Zhang, Xiu-wu Bian, Wenchao Zhou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The peptidyl-prolyl cis-trans isomerase Pin1 is a pivotal therapeutic target in cancers, but the regulation of Pin1 protein stability is largely unknown. High Pin1 expression is associated with SUMO1-modified protein hypersumoylation in glio
Externí odkaz:
https://doaj.org/article/68d6219593424984988e9b55888ae088
Autor:
Jia Shi, Peng Zhang, Xuchen Dong, Jiaqi Yuan, Yongdong Li, Suwen Li, Shan Cheng, Yifang Ping, Xingliang Dai, Jun Dong
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Chemo-resistance hinders the therapeutic efficacy of temozolomide (TMZ) in treating glioblastoma multiforme (GBM). Recurrence of GBM even after combination of maximal tumor resection, concurrent radio-chemotherapy, and systemic TMZ applocati
Externí odkaz:
https://doaj.org/article/8da74c1f61564890bb467c75e316aff1
Autor:
Yujing Sheng, Baomin Chen, Liang Liu, Suwen Li, Shilu Huang, Shan Cheng, Zhe Li, Yifang Ping, Zhigang Gong, Jun Dong
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e19034- (2023)
Metabolism remodelling of macrophages in the glioblastoma microenvironment contributes to immunotherapeutic resistance. However, glioma stem cell (GSC)-initiated lipid metabolism remodelling of transformed macrophages (tMΦs) and its effect on the gl
Externí odkaz:
https://doaj.org/article/bb8e34b56dc04cb09c6bee465c36e809
Autor:
Yan-Xia Wang, Haibo Wu, Yong Ren, Shengqing Lv, Chengdong Ji, Dongfang Xiang, Mengsi Zhang, Huimin Lu, Wenjuan Fu, Qing Liu, Zexuan Yan, Qinghua Ma, Jingya Miao, Ruili Cai, Xi Lan, Bin Wu, Wenying Wang, Yinhua Liu, Dai-Zhong Wang, Mianfu Cao, Zhicheng He, Yu Shi, Yifang Ping, Xiaohong Yao, Xia Zhang, Peng Zhang, Ji Ming Wang, Yan Wang, Youhong Cui, Xiu-Wu Bian
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Medulloblastoma (MB) is one of the most common childhood malignant brain tumors (WHO grade IV), traditionally divided into WNT, SHH, Group 3, and Group 4 subgroups based on the transcription profiles, somatic DNA alterations, and clinical ou
Externí odkaz:
https://doaj.org/article/c19b175391054b93946eadcdcf017196
Autor:
Quanyu Zhang, Huarong Zhang, Xiaowei Yan, Sicong Ma, Xiaohong Yao, Yu Shi, Yifang Ping, Mianfu Cao, Chengfei Peng, Shuai Wang, Min Luo, Chenghui Yan, Shuyang Zhang, Yaling Han, Xiuwu Bian
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
AimsTo investigate cardiac pathology in critically ill patients with coronavirus disease 2019 (COVID-19) and identify associations between pathological changes and clinical characteristics.MethodsThe present autopsy cohort study included hearts from
Externí odkaz:
https://doaj.org/article/fa0414244247446982951aa17082b9a9
Autor:
Longfei Gao, Wuqiang Guan, Min Wang, Huihan Wang, Jiali Yu, Qing Liu, Binlong Qiu, Yongchun Yu, Yifang Ping, Xiuwu Bian, Li Shen, Gang Pei
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 538-547 (2017)
Astrocytes, due to the proximity to neuronal lineage and capability to proliferate, are ideal starting cells to regenerate neurons. Human fetal astrocytes have been successfully converted into neuronal cells by small molecules, which offered a broade
Externí odkaz:
https://doaj.org/article/33929677d0d249d7a0a939129f32301e
Autor:
Qinghong Wang, Jijun Zhou, Bei Zhang, Zhiqiang Tian, Jun Tang, Yanhua Zheng, Zemin Huang, Yi Tian, Zhengcai Jia, Yan Tang, Jennifer C van Velkinburgh, Qing Mao, Xiuwu Bian, Yifang Ping, Bing Ni, Yuzhang Wu
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003410 (2013)
IL-23 regulates myriad processes in the innate and adaptive immune systems, and is a critical mediator of the proinflammatory effects exerted by Th17 cells in many diseases. In this study, we investigated whether and how hepatitis B virus (HBV) cause
Externí odkaz:
https://doaj.org/article/04cc8df84e4445d8b9b08a6b1f6a1259
Autor:
Xiaohong Yao, Yifang Ping, Ying Liu, Kequiang Chen, Teizo Yoshimura, Mingyong Liu, Wanghua Gong, Chong Chen, Qin Niu, Deyu Guo, Xia Zhang, Ji Ming Wang, Xiuwu Bian
Publikováno v:
PLoS ONE, Vol 8, Iss 12 (2013)
Externí odkaz:
https://doaj.org/article/eb6c0fbcbd514c03ae2d217db25f3939
Autor:
Xiaohong Yao, Yifang Ping, Ying Liu, Kequiang Chen, Teizo Yoshimura, Mingyong Liu, Wanghua Gong, Chong Chen, Qin Niu, Deyu Guo, Xia Zhang, Ji Ming Wang, Xiuwu Bian
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57188 (2013)
Human glioblastomas (GBM) are thought to be initiated by glioma stem-like cells (GSLCs). GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells. Here, we report a critical role of GSLCs in the forma
Externí odkaz:
https://doaj.org/article/a1d1d75cdfc74dea84e121fb1745d347
Autor:
Si Wang, Xiaohong Yao, Shuai Ma, Yifang Ping, Yanling Fan, Shuhui Sun, Zhicheng He, Yu Shi, Liang Sun, Shiqi Xiao, Moshi Song, Jun Cai, Jiaming Li, Rui Tang, Liyun Zhao, Chaofu Wang, Qiaoran Wang, Lei Zhao, Huifang Hu, Xindong Liu, Guoqiang Sun, Lu Chen, Guoqing Pan, Huaiyong Chen, Qingrui Li, Peipei Zhang, Yuanyuan Xu, Huyi Feng, Guo-Guang Zhao, Tianzi Wen, Yungui Yang, Xuequan Huang, Wei Li, Zhenhua Liu, Hongmei Wang, Haibo Wu, Baoyang Hu, Yong Ren, Qi Zhou, Jing Qu, Weiqi Zhang, Guang-Hui Liu, Xiu-Wu Bian
Publikováno v:
Nature Cell Biology
The lung is the primary organ targeted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), making respiratory failure a leading coronavirus disease 2019 (COVID-19)-related mortality. However, our cellular and molecular understanding of h