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Autor:
Utkarsh Chauhan, Luc G. Berthiaume, Raymond Lai, Wei-Feng Dong, Sunita Ghosh, Justine Lai, John R. Mackey, Yie-Wei Sim, Darryl D. Glubrecht, Erwan Beauchamp, Gilbert Bigras
Publikováno v:
Breast Cancer Research and Treatment
Purpose N-myristoyltransferases 1 and 2 (NMT1 and NMT2) catalyze the addition of 14-carbon fatty acids to the N-terminus of proteins. Myristoylation regulates numerous membrane-bound signal transduction pathways important in cancer biology and the pa