Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yideng, Liang"'
Autor:
Ivan D. Tarandovskiy, Stepan S. Surov, Leonid A. Parunov, Yideng Liang, Wojciech Jankowski, Zuben E. Sauna, Mikhail V. Ovanesov
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Thrombin generation (TG) and fibrin clot formation represent the central process of blood coagulation. Up to 95% of thrombin is considered to be generated after the clot is formed. However, this was not investigated in depth. In this study,
Externí odkaz:
https://doaj.org/article/dca2acebe37f4b8dbe886c06c41fd9bf
Autor:
Yideng Liang, Joseph W. Jackson, Samuel A. Woodle, Stepan S. Surov, Leonid A. Parunov, Dorothy E. Scott, Mark Weinstein, Timothy K. Lee, Mikhail V. Ovanesov
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Abstract Background Activated coagulation factor XIa (FXIa) is an impurity and primary source of procoagulant activity in thrombosis‐implicated immune globulin (IG) products. Several assays, of varying quality and precision are used to assess FXIa
Externí odkaz:
https://doaj.org/article/ab2eec995bec476b91c3b022656c3222
Autor:
Yanqun Xu, Yideng Liang, Leonid Parunov, Daryl Despres, Michael Eckhaus, Dorothy Scott, Mikhail Ovanesov, Evi B. Struble
Publikováno v:
Thrombosis Journal, Vol 18, Iss 1, Pp 1-10 (2020)
Abstract Background Pregnant women are at increased risk of thrombotic adverse events. Plasma derived immune globulin (IG) products, which are used in pregnancy for various indications, may contain procoagulant impurity activated coagulation factor X
Externí odkaz:
https://doaj.org/article/54e8e2e2d34546058d8303ab1176206b
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 944-945 (2020)
Externí odkaz:
https://doaj.org/article/b2f169bd185d433e85f9d7ad0aaab62e
Autor:
Leonid A Parunov, Yideng Liang, Qijin Lu, Alexey M Shibeko, Erik I. Tucker, Timothy K. Lee, Fazoil I Ataullakhanov, Dorothy Scott, Mikhail V Ovanesov
Publikováno v:
Blood Advances.
Inhibitors of coagulation factor (F) XIa are currently investigated as potential anticoagulant therapies. We hypothesized that circulating FXIa may be a potential target for these therapies. Using previous analyses of FXIa impurity in immune globulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25761cdb087100a2c10a3455f6660c82
https://doi.org/10.1182/bloodadvances.2022008743
https://doi.org/10.1182/bloodadvances.2022008743
Autor:
Yideng Liang, Leonid A. Parunov, Maria E Shea, Mikhail V Ovanesov, Stepan S Surov, Dorothy E. Scott, Timothy K Lee, Maitreyi Chattopadhyay
Publikováno v:
Nature Protocols. 16:3981-4003
Thrombin generation (TG) assays are used widely to investigate both diseases and drugs that impact thrombosis and bleeding. TG assays were also instrumental in the identification of thrombogenic impurities in immune globulin products, which were asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e943a833a9c492c283998a62fce4f47
https://doi.org/10.1038/s41596-021-00568-4
https://doi.org/10.1038/s41596-021-00568-4
Autor:
Joseph W Jackson, M J Weinstein, Dorothy E. Scott, Mikhail V Ovanesov, Leonid A. Parunov, Samuel A. Woodle, Timothy K Lee, Yideng Liang, Stepan S Surov
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Background Activated coagulation factor XIa (FXIa) is an impurity and primary source of procoagulant activity in thrombosis‐implicated immune globulin (IG) products. Several assays, of varying quality and precision are used to assess FXIa‐like pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1c222c4217df1a21ef8507b1bf991d
https://doi.org/10.1002/rth2.12467
https://doi.org/10.1002/rth2.12467
Autor:
Naoki Masuda, Qi Peng, Qing Li, Mali Jiang, Yideng Liang, Xiaofang Wang, Ming Zhao, Wenfei Wang, Christopher A. Ross, Wenzhen Duan
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 3, Pp 293-302 (2008)
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by chorea, incoordination, and shortened life-span, and by huntingtin inclusions and neurodegeneration. We previously screened the 1040 FDA-approved compounds
Externí odkaz:
https://doaj.org/article/81f1c45665904b3b8dff6263eb65e284
Autor:
Haibing Jiang, Michelle A. Poirier, Yideng Liang, Zhong Pei, Charlotte E. Weiskittel, Wanli W. Smith, Donald B. DeFranco, Christopher A. Ross
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 3, Pp 543-551 (2006)
Huntington's disease is a neurodegenerative disease caused by an expanded polyglutamine stretch within the huntingtin protein. Transfection of mutant huntingtin causes cell toxicity and depletion of CREB binding protein (CBP) or its recruitment into
Externí odkaz:
https://doaj.org/article/4ed2f9ac950b4141b00909f5664b4f03
Autor:
Xiao Fei He, Xiaofang Wang, Lino Tessarolo, Christopher A. Ross, Yong Huang, Mark Ren, Frederick C. Nucifora, Nicolas Arbez, Wanli W. Smith, Yideng Liang, Zhong Pei
Publikováno v:
Hum Mol Genet
Parkinson’s disease (PD) is a common neurodegenerative disease with a heterogeneous etiology that involves genetic and environmental factors or exogenous. Current LRRK2 PD animal models only partly reproduce the characteristics of the disease with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bb58300ef8c9cd40cf98f656fe6fae
https://doi.org/10.1093/hmg/ddz271
https://doi.org/10.1093/hmg/ddz271