Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yicong Wei"'
Autor:
Guoen Cai, Fabin Lin, Dihang Wu, Chenxin Lin, Huiyun Chen, Yicong Wei, Huidan Weng, Zhiting Chen, Minxia Wu, En Huang, Zucheng Ye, Qinyong Ye
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Mitochondria are essential organelles that perform important roles in cell biologies such as ATP synthesis, metabolic regulation, immunomodulatory, and apoptosis. Parkinson’s disease (PD) is connected with mitochondrial neuronal damage related to m
Externí odkaz:
https://doaj.org/article/fcdda279c2814c75a6a8865be54ffc66
Publikováno v:
Chinese Herbal Medicines. 15:298-309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f8581111c8888cfa9ebf97996260d75
https://doi.org/10.1016/j.chmed.2022.11.002
https://doi.org/10.1016/j.chmed.2022.11.002
Publikováno v:
Central nervous system agents in medicinal chemistry. 22(1)
Background: Depressive disorder is one of the most common mental diseases and has become one of the three major causes of disability worldwide. Although some of the pathological mechanisms have been analyzed, the corresponding drug therapy has only a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06e6067f8aa771d28f3b5fdaf3007e2
https://pubmed.ncbi.nlm.nih.gov/35260064
https://pubmed.ncbi.nlm.nih.gov/35260064
Publikováno v:
Behavioural Brain Research. 433:114006
Neuroinflammation is one of the main causes of sickness and depressive-like behavior. Rosmarinic acid (RA) has been shown to have a significant anti-neuroinflammatory effect. However, the protective effects and the underlying mechanism of RA on sickn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa16b15242c424ce59a8e805241b7b43
https://doi.org/10.1016/j.bbr.2022.114006
https://doi.org/10.1016/j.bbr.2022.114006
Publikováno v:
BioMed Research International, Vol 2021 (2021)
BioMed Research International
BioMed Research International
Major depressive disorder (MDD) is a prevalent, chronic, and relapse-prone psychiatric disease. However, the intermediate molecules resulting from stress and neurological impairment in different brain regions are still unclear. To clarify the patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dace20bca042aabbd0549c098adc336b
https://doaj.org/article/2d19b5f2004849b594f6ede97ac96f48
https://doaj.org/article/2d19b5f2004849b594f6ede97ac96f48
Publikováno v:
Behavioural Brain Research. 423:113775
The NLRP3 inflammasome activation and neuroinflammation play a crucial role in nerve damage, which can lead to sickness and depressive-like behavior. Dihydromyricetin (DMY) is an important flavanone extracted from Ampelopsis grossedentata. It has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f386acdc1b989959b01917060d00cb0
https://doi.org/10.1016/j.bbr.2022.113775
https://doi.org/10.1016/j.bbr.2022.113775
Publikováno v:
Inflammation. 44(1)
Microglia are resident macrophage-like cells in the central nervous system (CNS). The induction of microglial activation dampens neuroinflammation-related diseases by promoting microglial (re)polarization to the anti-inflammatory (M2) phenotype and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bae6a101eb237492e15a089e9c88221
https://pubmed.ncbi.nlm.nih.gov/32940818
https://pubmed.ncbi.nlm.nih.gov/32940818
Autor:
Yicong Wei, Yingzheng Wang, Haimian Hong, Guizhu Hong, Chen Lidian, Xiaoqin Zhang, John Brown, Kedan Chu, Wenfang Lai
Publikováno v:
Inflammation. 40:1297-1309
Salidroside is being investigated for its therapeutic potential in stroke because it is neuroprotective over an extended therapeutic window of time. In the present study, we investigated the mechanisms underlying the anti-inflammatory effects of sali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd182f16219bbba0c6d3d3f835a314b5
https://doi.org/10.1007/s10753-017-0573-x
https://doi.org/10.1007/s10753-017-0573-x
Publikováno v:
Inflammation. 41(2)
The excessive activation of microglia plays a key role in the pathogenesis of neurodegenerative diseases. The neuroprotective properties of rosmarinic acid have been reported in a variety of disease models both in vitro and in vivo; however, the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b42f599eb7c0e27195303bfc36945a
https://pubmed.ncbi.nlm.nih.gov/29318480
https://pubmed.ncbi.nlm.nih.gov/29318480
Autor:
Shaoping Zhang, Guizhu Hong, Qing Xiang, Wenfang Lai, Yicong Wei, Jingti Deng, Chu Kedan, Xue Tian, John Brown
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 29(4)
Inhibition of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) represents a therapeutic target for treating hyperglycemia in type 2 diabetes. Here, we investigate the effects of 11β-HSD1 on the innate immune response of adipocytes to produce pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847bcb459a649441b60f43489bc3b262
https://pubmed.ncbi.nlm.nih.gov/25734515
https://pubmed.ncbi.nlm.nih.gov/25734515