Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Yick Fu Wong"'
Autor:
Mari K. Halle, Aishwarya Sundaresan, Jianqing Zhang, Chandra Sekhar Pedamallu, Vinodh Srinivasasainagendra, Jessica Blair, Dewey Brooke, Bjørn I. Bertelsen, Kathrine Woie, Sadeep Shrestha, Hemant Tiwari, Yick Fu Wong, Camilla Krakstad, Akinyemi I. Ojesina
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Despite recent advances in the prevention of cervical cancer, the disease remains a leading cause of cancer-related deaths in women worldwide. By applying the GISTIC2.0 and/or the MutSig2CV algorithms on 430 whole-exome-sequenced cervical ca
Externí odkaz:
https://doaj.org/article/b3ff1a185aaf4482bae4d581122715c0
Autor:
Aishwarya Sundaresan, Chandra Sekhar Pedamallu, Vinodh Srinivasasainagendra, Yick Fu Wong, Kathrine Woie, Akinyemi I. Ojesina, Camilla Krakstad, Mari K Halle, Bjørn I. Bertelsen, Jessica Blair, Jianqing Zhang, Hemant K. Tiwari, Sadeep Shrestha, Dewey Brooke
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
NPJ Genomic Medicine
NPJ Genomic Medicine
Despite recent advances in the prevention of cervical cancer, the disease remains a leading cause of cancer-related deaths in women worldwide. By applying the GISTIC2.0 and/or the MutSig2CV algorithms on 430 whole-exome-sequenced cervical carcinomas,
Autor:
Danny T M Leung, Pak-Leong Lim, Tak-Hong Cheung, Raymond R Y Wong, So-Fan Yim, Margaret H L Ng, Frankie C H Tam, Tony K H Chung, Yick-Fu Wong
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160412 (2016)
We investigated whether circulating osteopontin (OPN) could be used as a biomarker for cervical cancer. We employed a monoclonal antibody (mAb 659) specific for the unique and intact thrombin-sensitive site in OPN using an inhibition ELISA. We found
Externí odkaz:
https://doaj.org/article/9cdd2c05b1f74df88a4c4e85c329e859
Autor:
Aaron R. Thorner, Suet Ying Yeung, Yi Mu, Audrey Dalgarno, Raymond R.Y. Wong, Mei Yung Yu, Michael J. Worley, Tak Hong Cheung, So Fan Yim, Yick Fu Wong, Vivian W. Wang, Michael S. Lawrence, Christopher P. Crum, Chandra Sekhar Pedamallu, Akinyemi I. Ojesina, Graeme Doran, Anwesha Nag, Rossa W.K. Chiu, Bruce M. Wollison, Neil S. Horowitz, Kei Man Lau, Ross S. Berkowitz, Jacqueline Ho Sze Lee, Kevin M. Elias, Matthew D. Ducar, Samuel C. Mok, Shuk On Annie Leung, Tony K.H. Chung, Paul K.S. Chan, Michelle Davis, Lo Wong
Publikováno v:
Cancers
Volume 13
Issue 13
Cancers, Vol 13, Iss 3218, p 3218 (2021)
Volume 13
Issue 13
Cancers, Vol 13, Iss 3218, p 3218 (2021)
Simple Summary There is limited information about genomic markers, especially for cervical adenocarcinoma treatment decisions. In this prospective study, it was found that nonsynonymous PIK3CA mutation detected in the patient’s circulating DNA coll
Autor:
Keith W.K. Lo, Tak Hong Cheung, Nelson S.S. Siu, Tony K.H. Chung, Ross S. Berkowitz, Apple C.M. Yeung, Martin C.S. Wong, Stephen Fiascone, Paul K.S. Chan, Raymond R.Y. Wong, Mei Yun Yu, Zigui Chen, Michael J. Worley, Rossa W.K. Chiu, Kevin M. Elias, So Fan Yim, Yick Fu Wong
Publikováno v:
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 114
Background A blood test to serve as a tumor marker for cervical cancer would be useful to clinicians to guide treatment and provide an early signal for recurrence. The development of droplet digital PCR has enabled the detection of HPV DNA in patient
Autor:
Tak Hong Cheung, Christopher P. Crum, Aaron R. Thorner, Taymaa May, Vivian W. Wang, Tony K.H. Chung, Akinyemi I. Ojesina, Kevin M. Elias, Matthew D. Ducar, Raymond R.Y. Wong, Mei Y. Yu, Tat San Lau, Michael J. Worley, So Fan Yim, Yick Fu Wong, Michael S. Lawrence, Chandra Sekhar Pedamallu, Graeme Doran, Loucia K.Y. Chan, Samuel S. Freeman, Matthew Meyerson, Menachem Fromer, Paul K.S. Chan, Gad Getz, Katharine M. Esselen, Joseph Kwong, David I. Smith, Ross S. Berkowitz, Laura E. MacConaill, Paul Van Hummelen
Publikováno v:
International Journal of Cancer. 137:776-783
Although the rates of cervical squamous cell carcinoma have been declining, the rates of cervical adenocarcinoma are increasing in some countries. Outcomes for advanced cervical adenocarcinoma remain poor. Precision mapping of genetic alterations in
Autor:
Vivian W. Wang, Tony K.H. Chung, Keith W.K. Lo, David I. Smith, So Fan Yim, Yick Fu Wong, Raymond R.Y. Wong, Ida P.C. Lee, Mei Yun Yu, Tak Hong Cheung, Rossa W.K. Chiu, Michael J. Worley, Kitty K.M. Lau, Kevin M. Elias, Ross S. Berkowitz, Stephen Fiascone
Publikováno v:
Gynecologic oncology. 146(2)
Introduction Cervical cancer is the fourth most common female cancer worldwide. The prognosis for women with advanced-stage or recurrent cervical cancer remains poor and response to treatment is variable. Standardized management protocols leave littl
Autor:
Tony K.H. Chung, Chi Chiu Wang, Hoi Kin Wong, Ka Fai To, Yick Fu Wong, Tao Tang, Tak Hong Cheung, Wenyi Gu, Mei-Yung Yu, Kwong Wai Choy
Publikováno v:
Gynecologic Oncology. 129:199-208
Objectives The purposes of this study were to identify aberrantly expressed miRNAs and investigate their pathogenic roles in cervical cancer. Methods miRNA expression was assessed in cervical cancer cell lines, micro-dissected normal cervical epithel
Autor:
Pak-Leong Lim, Tony K.H. Chung, Raymond R.Y. Wong, Margaret H.L. Ng, So Fan Yim, Yick Fu Wong, Danny T. M. Leung, Tak Hong Cheung, Frankie C. H. Tam
Publikováno v:
PLOS ONE
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0160412 (2016)
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0160412 (2016)
We investigated whether circulating osteopontin (OPN) could be used as a biomarker for cervical cancer. We employed a monoclonal antibody (mAb 659) specific for the unique and intact thrombin-sensitive site in OPN using an inhibition ELISA. We found
Autor:
Mei Yun Yu, Tony K.H. Chung, Tak Hong Cheung, Yin Mei Wong, Man Wah Pang, Katherine W.Y. Wong, Graeme Doran, Po Ting Tsang, Michael J. Birrer, Ngar Yee Huen, So Fan Yim, Yick Fu Wong, Samuel C. Mok, Vivian W. Wang, Chen Li, Nelson S.S. Siu, Keith W.K. Lo, David I. Smith, Albert Y. K. Cheung, Ka Fei To
Publikováno v:
International Journal of Cancer. 124:1358-1365
The objective of this study, a parallel study to global gene expression profiling, was to identify dysregulated microRNAs (miRNAs) associated with endometrioid endometrial adenocarcinoma (EEC), examine their correlation with clinico-pathological char