Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yichuan Xia"'
Autor:
Wanlin Yang, Min Jin, Yuting Gu, Xiaonan Zhao, Lingqiao Zhu, Shan He, Hui Wang, Xinyuan Ding, Bei Wang, Tingwang Jiang, Yichuan Xiao, Guoqiang Zhou, Jiefang Huang, Yanyun Zhang
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Introduction Mesenchymal stromal cell (MSC)-based cell therapy is a promising approach for various inflammatory disorders based on their immunosuppressive capacity. Osteopontin (OPN) regulates several cellular functions including tissue repa
Externí odkaz:
https://doaj.org/article/27d7e8b4347e43108212892d4a63bef7
Autor:
Hanbo Pan, Yu Tian, Siyu Pei, Wanlin Yang, Yanyang Zhang, Zenan Gu, Hongda Zhu, Ningyuan Zou, Jiaqi Zhang, Long Jiang, Yingjie Hu, Shengping Shen, Kai Wang, Haizhen Jin, Ziming Li, Yanyun Zhang, Yichuan Xiao, Qingquan Luo, Hui Wang, Jia Huang
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-24 (2024)
Abstract Background Non-small cell lung cancer (NSCLC) is one of the predominant malignancies globally. Percutaneous thermal ablation (PTA) has gained widespread use among NSCLC patients, with the potential to elicit immune responses but limited ther
Externí odkaz:
https://doaj.org/article/c1ea960d84b14322a3389936d2f41a36
Autor:
Chenxin Xu, Guoyu Chen, Bo Yu, Bowen Sun, Yingwen Zhang, Mingda Zhang, Yi Yang, Yichuan Xiao, Shi‐Yuan Cheng, Yanxin Li, Haizhong Feng
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract The factors driving glioma progression remain poorly understood. Here, the epigenetic regulator TRIM24 is identified as a driver of glioma progression, where TRIM24 overexpression promotes HRasV12 anaplastic astrocytoma (AA) progression into
Externí odkaz:
https://doaj.org/article/4533c20a70e64f66876871ae4421263b
Autor:
Xiaoqin Li, Fen Xiong, Zhangmin Hu, Qing Tao, Yufei Yang, Xuehan Qiao, Chen Peng, Yuchun Jiang, Miao Han, Kebin Dong, Yi Hua, Wei Zhang, Min Xu, Weiguo Long, Yichuan Xiao, Deqiang Wang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Novel biomarkers are required in gastric cancer (GC) treated by immunotherapy. Epstein-Barr virus (EBV) infection induces an immune-active tumor microenvironment, while its association with immunotherapy response is still controve
Externí odkaz:
https://doaj.org/article/cad2de92932d480585a6074f7749ff6d
Autor:
Eric I. Felner, Andrea K. Steck, Michael J. Haller, Yichuan Xia, Ramineh Zoka, Joseph A Hedrick, Jocelyn H. Leu, T Ger Study Investigators, Yinglei Li, Mark R. Rigby, Teresa Quattrin, Frank Vercruysse
Publikováno v:
N Engl J Med
Type 1 diabetes is an autoimmune disease characterized by progressive loss of pancreatic beta cells. Golimumab is a human monoclonal antibody specific for tumor necrosis factorIn this phase 2, multicenter, placebo-controlled, double-blind, parallel-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348dd322d47360729504372f1284867a
https://pubmed.ncbi.nlm.nih.gov/33207099
https://pubmed.ncbi.nlm.nih.gov/33207099
Autor:
Yuxiao Liu, Weitong Su, Zhengshuai Liu, Zhimin Hu, Jiaxin Shen, Zengpeng Zheng, Dong Ding, Wei Huang, Wenjing Li, Genxiang Cai, Shuang Wei, Ni Li, Xia Fang, Hong Li, Jun Qin, Haibing Zhang, Yichuan Xiao, Yan Bi, Aoyuan Cui, Chunxiang Zhang, Yu Li
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Chronic adipose tissue inflammation accompanied by macrophage accumulation and activation is implicated in the pathogenesis of insulin resistance and type 2 diabetes in humans. The transcriptional coregulator CREBZF is a key factor in hepati
Externí odkaz:
https://doaj.org/article/da1da277e59d4d8b915f8ac0d398d37d
Autor:
Shuning Ding, Niu Qiao, Qingchen Zhu, Yiwei Tong, Shengyue Wang, Xiaosong Chen, Qiang Tian, Yichuan Xiao, Kunwei Shen
Publikováno v:
Cancer Communications, Vol 43, Iss 6, Pp 661-684 (2023)
Abstract Background Characterizing the unique immune microenvironment of each tumor is of great importance for better predicting prognosis and guiding cancer immunotherapy. However, the unique features of the immune microenvironment of triple negativ
Externí odkaz:
https://doaj.org/article/0045da13b0e542e6ae568c59e629efd0
Autor:
Rongjing Wang, Minghui Wang, Siyu Pei, Yuchao Zhang, Shiwei Guo, Wei Guo, Zhenchuan Wu, Hailong Wang, Yizhe Li, Yufei Zhu, Ling-Hua Meng, Jingyu Lang, Gang Jin, Yichuan Xiao, Landian Hu, Xiangyin Kong
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102616- (2023)
Summary: Here, we present a protocol for exploring the effects of PPP1R15A inhibitor, Sephin1, on antitumor immunity of B16F1 subcutaneous tumor in mice. We describe steps for constructing single-cell transcriptome and TCR libraries, sequencing, and
Externí odkaz:
https://doaj.org/article/bd0396584b0744d5bc6a1400e4483272
Autor:
Martina Tufano, Laura Marrone, Chiara D’Ambrosio, Valeria Di Giacomo, Simona Urzini, Yichuan Xiao, Monica Matuozzo, Andrea Scaloni, Maria Fiammetta Romano, Simona Romano
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-12 (2023)
Abstract FKBP51 plays a relevant role in sustaining cancer cells, particularly melanoma. This cochaperone participates in several signaling pathways. FKBP51 forms a complex with Akt and PHLPP, which is reported to dephosphorylate Akt. Given the recen
Externí odkaz:
https://doaj.org/article/fb65ffadfcf849cf9982147d21fb65f9
Autor:
Alexa Kollmeier, Andrew J. Greenspan, Paul J. Dunford, Yichuan Xia, Xie L. Xu, Bei Zhou, Robin L. Thurmond, Bin Chen, Klaus Francke
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 350:181-187
The histamine H4 receptor (H4R) is a promising target for the treatment of pruritus. A clinical study was conducted to evaluate the safety and efficacy of the H4R antagonist, JNJ 39758979 [(R)-4-(3-amino-pyrrolidin-1-yl)-6-isopropyl-pyrimidin-2-ylami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc4cc4a164961c4a9ede3a3f4a2b1eb8
https://doi.org/10.1124/jpet.114.215749
https://doi.org/10.1124/jpet.114.215749