Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yichen Xiang"'
Publikováno v:
eLife, Vol 11 (2022)
Adenosine deaminases acting on RNA (ADARs) can be repurposed to enable programmable RNA editing, however their exogenous delivery leads to transcriptome-wide off-targeting, and additionally, enzymatic activity on certain RNA motifs, especially those
Externí odkaz:
https://doaj.org/article/73940bf37fb4455a9643d0af3f0b4fdc
Publikováno v:
Methods. 205:158-166
Adenosine deaminases acting on RNA (ADARs) can be repurposed to achieve site-specific A-to-I RNA editing by recruiting them to a target of interest via an ADAR-recruiting guide RNA (adRNA). In this chapter, we present details towards experimental met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25883551f823783ab955cce0b0ea2c68
https://doi.org/10.1016/j.ymeth.2022.06.011
https://doi.org/10.1016/j.ymeth.2022.06.011
Autor:
Dhruva Katrekar, James Yen, Yichen Xiang, Anushka Saha, Dario Meluzzi, Yiannis Savva, Prashant Mali
Publikováno v:
Nature biotechnology, vol 40, iss 6
Recruiting endogenous adenosine deaminases using exogenous guide RNAs to edit cellular RNAs is a promising therapeutic strategy, but editing efficiency and durability remain low using current guide RNA designs. In this study, we engineered circular A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e9dbb4347070021f13af6a7fb1183b
https://escholarship.org/uc/item/5zq150jc
https://escholarship.org/uc/item/5zq150jc
Publikováno v:
IEEE transactions on haptics. 15(3)
Unsorted three dimensional (3D) points are commonly acquired from modern tools and they become popular in many virtual reality applications. In order to produce the haptic feedback to enrich the interaction with the captured models, the point clouds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585cf6b89c6b6715329083dee14b45fd
https://pubmed.ncbi.nlm.nih.gov/35389870
https://pubmed.ncbi.nlm.nih.gov/35389870
Autor:
Yichen Xiang, Zupei Yang, Di Wu, Zhanhui Peng, Pengfei Liang, Bi Chen, Xiaolian Chao, Hui Peng
Publikováno v:
Ceramics International. 45:11899-11904
The molten salt method was adopted in this work to synthesize CdCu3Ti4O12 precursor powders and was found capable of notably reducing the sintering temperature. It was also found that the grain size gradually increases and the grain shape changes fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d35fa4c3863258ef0187fdc52ce7dd
https://doi.org/10.1016/j.ceramint.2019.03.075
https://doi.org/10.1016/j.ceramint.2019.03.075
Autor:
Di Wu, Pengfei Liang, Xiaolian Chao, Zhanhui Peng, Zupei Yang, Hui Peng, Yichen Xiang, Xiaobin Zhou
Publikováno v:
Journal of Alloys and Compounds. 783:423-427
Effects of sintering condition on dielectric properties and microstructure were systematically investigated in (Ag1/4Ta3/4)0.005Ti0.995O2 ceramics. A giant dielectric constant of ∼9831 (1 kHz) and a relatively low dielectric loss of ∼0.041 (1 kHz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7660267629ddc790c781f112ba6647dd
https://doi.org/10.1016/j.jallcom.2018.12.321
https://doi.org/10.1016/j.jallcom.2018.12.321
Publikováno v:
Journal of Alloys and Compounds. 778:391-397
A′ site substitution in perovskite Y2/3Cu3-xZnxTi4O12 (x = 0.00, 0.03, 0.05, 0.07, 0.1) was designed and synthesized using solid state reaction method. Zn doping was responsible for the improved dielectric properties and nonlinear behaviors of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bffa1721aa0a7bedc20d3b6784aed79
https://doi.org/10.1016/j.jallcom.2018.11.104
https://doi.org/10.1016/j.jallcom.2018.11.104
Autor:
Prashant Mali, Yichen Xiang, Yiannis A. Savva, Dario Meluzzi, James Yen, Dhruva Katrekar, Anushka Saha
Akin to short-hairpin RNAs and antisense oligonucleotides which efficaciously recruit endogenous cellular machinery such as Argonaute and RNase H to enable targeted RNA knockdown, simple long antisense guide RNAs (1) can recruit endogenous adenosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53efd543fb08ce93aa7b5971010ac6fb
https://doi.org/10.1101/2021.01.12.426286
https://doi.org/10.1101/2021.01.12.426286
Publikováno v:
Ceramics International. 44:20311-20321
An effective strategy to improve the dielectric properties of CdCu3Ti4O12 ceramics was proposed via doping with Zr4+ substituting in Ti4+ sites using the sol-gel method. SEM images of samples with high densification show a fine-grained and uniform-si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce48b3eb6dba27d0020c00fb137c513a
https://doi.org/10.1016/j.ceramint.2018.08.019
https://doi.org/10.1016/j.ceramint.2018.08.019