Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yichao Gan"'
Autor:
Kaijie Qiu, Qing Xia, Hao Chen, Qiong Ye, Haixiang Mao, Mei Tian, Yichao Gan, Qinyuan Huang, Haibiao Wang, Shiwei Duan
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21851- (2023)
Hepatocellular carcinoma (HCC), ranking as the seventh most prevalent cancer worldwide, poses a significant health challenge. Actinidia chinensis Planch Root extracts (acRoots), a traditional Chinese medicine, has exhibited promising inhibitory effec
Externí odkaz:
https://doaj.org/article/5ebb98b492764755ac2cfd84b003b4fa
Autor:
Jiawei Zhang, Yichao Gan, Hongzhi Li, Jie Yin, Xin He, Liming Lin, Senlin Xu, Zhipeng Fang, Byung-wook Kim, Lina Gao, Lili Ding, Eryun Zhang, Xiaoxiao Ma, Junfeng Li, Ling Li, Yang Xu, David Horne, Rongzhen Xu, Hua Yu, Ying Gu, Wendong Huang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
CDK2 can drive the proliferation of cancer cells. Here, the authors screened for a non-ATP competitive inhibitor of the CDK2/cylinA complex and find that Homoharringtonine can disrupt the complex and promote the degradation of CDK2.
Externí odkaz:
https://doaj.org/article/ac83cddd29e447fc91fa01e2387d3f72
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract The Myc proto-oncogene family consists of three members, C-MYC, MYCN, and MYCL, which encodes the transcription factor c-Myc (hereafter Myc), N-Myc, and L-Myc, respectively. Myc protein orchestrates diverse physiological processes, including
Externí odkaz:
https://doaj.org/article/b53263a7bd8a45e79bf9541602dd52c8
Autor:
Yinghui Zhu, Xin He, Shu Li, Yichao Gan, Zheng Li, Hanying Wang, Haojie Dong, Lei Zhang, Sheng‐Li Xue, Yang Xu, Ling Li
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 3, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/1ab069c3921b48ffa3ee677ef4f9d103
Autor:
Yichao Gan, Chen Wang, Yunyun Chen, Linxin Hua, Hui Fang, Shu Li, Shoujie Chai, Yang Xu, Jiawei Zhang, Ying Gu
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1093 (2023)
Liver cancer, consisting mainly of hepatocellular carcinoma, is the third leading cause of cancer-related mortality worldwide. Despite advances in targeted therapies, these approaches remain insufficient in meeting the pressing clinical demands. Here
Externí odkaz:
https://doaj.org/article/fc9776c0975e4015bc201cdb018a2ce9
Autor:
Wendong Huang, Rongzhen Xu, Yun Yen, Jun Wu, Yafan Wang, Guiyu Lou, Jinfen Tang, Hong Zhou, Yichao Gan, Carl Van Ness, Xiaoqiong Wang, Xiaoxiao Ma, Tao Li, Zhipeng Meng
XLSX file, 12K, Phosphorylation of CAMKII in liver cancer patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d22c93ddf8c87b43b67b75a6ae4adb
https://doi.org/10.1158/1535-7163.22497724
https://doi.org/10.1158/1535-7163.22497724
Autor:
Wendong Huang, Rongzhen Xu, Yun Yen, Jun Wu, Yafan Wang, Guiyu Lou, Jinfen Tang, Hong Zhou, Yichao Gan, Carl Van Ness, Xiaoqiong Wang, Xiaoxiao Ma, Tao Li, Zhipeng Meng
XLSX file, 11K, Sphere formation (2 independent trials).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701545c235b771520941454f4265dfff
https://doi.org/10.1158/1535-7163.22497727.v1
https://doi.org/10.1158/1535-7163.22497727.v1
Autor:
Wendong Huang, Rongzhen Xu, Yun Yen, Jun Wu, Yafan Wang, Guiyu Lou, Jinfen Tang, Hong Zhou, Yichao Gan, Carl Van Ness, Xiaoqiong Wang, Xiaoxiao Ma, Tao Li, Zhipeng Meng
PDF file, 1752K, Figure S1. (Related to Figure 2) BBM suppresses the xenograft growth of Huh7 and SK-Hep-1 cells; Figure S2. (Related to Figure 3) BBM is localized in cytoplasm and affects cell survival; Figure S3. (Related to Figure 4) BBM suppresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5137751eebdb1195a2d5985c95a09c11
https://doi.org/10.1158/1535-7163.22497733
https://doi.org/10.1158/1535-7163.22497733
Autor:
Wendong Huang, Rongzhen Xu, Yun Yen, Jun Wu, Yafan Wang, Guiyu Lou, Jinfen Tang, Hong Zhou, Yichao Gan, Carl Van Ness, Xiaoqiong Wang, Xiaoxiao Ma, Tao Li, Zhipeng Meng
PDF file, 51K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e3d4e75607599d4b87c0518e8d63c8
https://doi.org/10.1158/1535-7163.22497736.v1
https://doi.org/10.1158/1535-7163.22497736.v1
Autor:
Wendong Huang, Rongzhen Xu, Yun Yen, Jun Wu, Yafan Wang, Guiyu Lou, Jinfen Tang, Hong Zhou, Yichao Gan, Carl Van Ness, Xiaoqiong Wang, Xiaoxiao Ma, Tao Li, Zhipeng Meng
XLSX file, 9K, IC50s of berbamine on liver cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179eb82e66fbd606492a842a151c0969
https://doi.org/10.1158/1535-7163.22497730.v1
https://doi.org/10.1158/1535-7163.22497730.v1