Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Yibing, Yin"'
Publikováno v:
Experimental Biology and Medicine, Vol 249 (2024)
Current pneumococcal vaccines, including the pneumococcal polysaccharide (PPV23) and conjugate (PCV13) vaccines, offer protection against specific serotypes but pose risks of serotype replacement that can alter the composition of the nasopharyngeal m
Externí odkaz:
https://doaj.org/article/3d41bb798f634133bfb822f3f53f2a60
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
The detoxified pneumolysin derivative ΔA146Ply has been proven to have a direct anti-triple negative breast cancer effect by our group, but its work model remains unclear. In this study, we focused on its ability to inhibit triple-negative breast ca
Externí odkaz:
https://doaj.org/article/8445f70694ce4bf2905658613fb93402
Autor:
Miao Yao, Kun Wang, Guangming Song, Yumeng Hu, Jiali Chen, Tingting Li, Longying Liang, Jie Wu, Hongmei Xu, Libin Wang, Yuqiang Zheng, Xuemei Zhang, Yibing Yin, Shifei Yao, Kaifeng Wu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Competence development is essential for bacterial transformation since it enables bacteria to take up free DNA from the surrounding environment. The regulation of teichoic acid biosynthesis is tightly controlled during pneumococcal competence; howeve
Externí odkaz:
https://doaj.org/article/040b41b1ca7f4c03a1717715fbbf1c10
Autor:
Shifei Yao, Danlin Weng, Yan Wang, Yanyu Zhang, Qi Huang, Kaifeng Wu, Honghui Li, Xuemei Zhang, Yibing Yin, Wenchun Xu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Early microbial exposure is associate with protective allergic asthma. We have previously demonstrated that Streptococcus pneumoniae aminopeptidase N (PepN), one of the pneumococcal components, inhibits ovalbumin (OVA) -induced ai
Externí odkaz:
https://doaj.org/article/1232889167fe4ffe8ab37635598f9a59
Autor:
Bichen Liu, Jun Huang, Jiangming Xiao, Wenlong Xu, Hong Zhang, Yuan Yuan, Yibing Yin, Xuemei Zhang
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background The efficacy of current surgery and chemotherapy for triple negative breast cancer (TNBC) is limited due to heterogenous and immunosuppressive tumor microenvironment (TME). Tumor associated macrophages (TAMs), which are regarded a
Externí odkaz:
https://doaj.org/article/901e293f08f44f25841c32573f07679e
Autor:
Qianqian Tu, Xiaoyan Yu, Wei Xie, Yetao Luo, Hong Tang, Kai Chen, Yanting Ruan, Yue Li, Jie Zhou, Yibing Yin, Dapeng Chen, Zhixin Song
Publikováno v:
International Journal of Infectious Diseases, Vol 125, Iss , Pp 103-113 (2022)
ABSTRACT: Objectives: Bacterial pneumonia is a common serious infectious disease with high morbidity and mortality. Prokineticin 2 (PK2) has recently been identified as a novel immunomodulator in a variety of diseases; however, its role in bacterial
Externí odkaz:
https://doaj.org/article/bf88f6eaaef440328efdd98757159f79
Autor:
Yapeng Zhang, Jinghui Zhang, Jiangming Xiao, Hanyi Wang, Rui Yang, Xinlin Guo, Yuqiang Zheng, Yibing Yin, Xuemei Zhang
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Natural transformation plays an important role in the formation of drug-resistant bacteria. Exploring the regulatory mechanism of natural transformation can aid the discovery of new antibacterial targets and reduce the emergence of drug-resi
Externí odkaz:
https://doaj.org/article/2b1fefe28a8b4aaa83e79bcccdbfeef6
Autor:
Shengnan Xiao, Weicai Suo, Jinghui Zhang, Xuemei Zhang, Yibing Yin, Xinlin Guo, Yuqiang Zheng
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2366-2381 (2021)
Global transcriptional regulators are prevalent in gram-positive pathogens. The transcriptional regulators of the Mga/AtxA family regulate target gene expression by directly binding to the promoter regions, that results in the coordinated expression
Externí odkaz:
https://doaj.org/article/cf63a33d76e14c61bdc6aa127e42f2bc
Autor:
Jiayu Liu, Xiaofei Lai, Renlin Yu, Hao Ding, Haobo Bai, Zhubin Yang, Yibing Yin, Fang Xu, Ju Cao
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010873 (2022)
Candida albicans is the most frequent pathogen of fungal sepsis associated with substantial mortality in critically ill patients and those who are immunocompromised. Identification of novel immune-based therapeutic targets from a better understanding
Externí odkaz:
https://doaj.org/article/a8c934c029104ce6b029f993a92d9f12
Autor:
Zhaoche Shu, Jun Yuan, Hong Wang, Jinghui Zhang, Sijie Li, Hong Zhang, Yusi Liu, Yibing Yin, Xuemei Zhang
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 270-282 (2020)
Macrophage is essential for host anti-bacterial defense by directly eliminating invading microbes and inducing a series of immune reactions. Here we identified a Streptococcus pneumoniae protein, PepO, as a TLR2/TLR4 bi-ligand. We found that PepO enh
Externí odkaz:
https://doaj.org/article/c692bbc601774142a5344d482249723a