Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yiannis Drosos"'
Autor:
Yiannis Drosos, Eumorphia G. Konstantakou, Aggeliki-Stefania Bassogianni, Konstantinos-Stylianos Nikolakopoulos, Dimitra G. Koumoundourou, Sophia P. Markaki, Ourania E. Tsitsilonis, Gerassimos E. Voutsinas, Dimitrios Valakos, Ema Anastasiadou, Dimitris Thanos, Athanassios D. Velentzas, Dimitrios J. Stravopodis
Publikováno v:
Cancers, Vol 15, Iss 14, p 3730 (2023)
Bladder cancer (BLCA) is the sixth most common type of cancer and has a dismal prognosis if diagnosed late. To identify treatment options for BLCA, we systematically evaluated data from the Broad Institute DepMap project. We found that urothelial BLC
Externí odkaz:
https://doaj.org/article/b5b519b2634543698866d9e451ed47ef
Autor:
Yiannis Drosos, Geoffrey Neale, Jianming Ye, Leena Paul, Emin Kuliyev, Anirban Maitra, Anna L Means, M Kay Washington, Jerold Rehg, David B Finkelstein, Beatriz Sosa-Pineda
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 3, Pp 172-184 (2016)
The current paradigm of pancreatic neoplastic transformation proposes an initial step whereby acinar cells convert into acinar-to-ductal metaplasias, followed by progression of these lesions into neoplasias under sustained oncogenic activity and infl
Externí odkaz:
https://doaj.org/article/5d87181b5cc147919209db8cc85fef3c
Autor:
Charles W.M. Roberts, William C. Hahn, Stuart L. Schreiber, Elizabeth A. Stewart, Cory M. Johannessen, Prafulla C. Gokhale, Hong L. Tiv, Lauren Hoffmann, Kaley Blankenship, Burgess B. Freeman, Xiaofeng Wang, Andrew O. Giacomelli, Brinton Seashore-Ludlow, Pilar Ramos, Kaeli M. Mathias, Yiannis Drosos, Hsien-Chao Chou, Guillaume Kugener, Andrew L. Hong, Mariana DoCarmo, Lisa Brenan, Minh-Tam Pham, Taylor E. Arnoff, Matthew G. Rees, Elaine M. Oberlick, Thomas P. Howard
Raw data for follow-up xenograft studies. Note different tabs for each xenograft type.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cf006969ed16c887b51d095fc8b4cf
https://doi.org/10.1158/1078-0432.22476111.v1
https://doi.org/10.1158/1078-0432.22476111.v1
Autor:
Charles W.M. Roberts, William C. Hahn, Stuart L. Schreiber, Elizabeth A. Stewart, Cory M. Johannessen, Prafulla C. Gokhale, Hong L. Tiv, Lauren Hoffmann, Kaley Blankenship, Burgess B. Freeman, Xiaofeng Wang, Andrew O. Giacomelli, Brinton Seashore-Ludlow, Pilar Ramos, Kaeli M. Mathias, Yiannis Drosos, Hsien-Chao Chou, Guillaume Kugener, Andrew L. Hong, Mariana DoCarmo, Lisa Brenan, Minh-Tam Pham, Taylor E. Arnoff, Matthew G. Rees, Elaine M. Oberlick, Thomas P. Howard
Purpose:Rhabdoid tumors are devastating pediatric cancers in need of improved therapies. We sought to identify small molecules that exhibit in vitro and in vivo efficacy against preclinical models of rhabdoid tumor.Experimental Design:We screened eig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea9a68f47fd3df93b1ed379bcbf43b5
https://doi.org/10.1158/1078-0432.c.6529299.v1
https://doi.org/10.1158/1078-0432.c.6529299.v1
Autor:
Charles W.M. Roberts, William C. Hahn, Stuart L. Schreiber, Elizabeth A. Stewart, Cory M. Johannessen, Prafulla C. Gokhale, Hong L. Tiv, Lauren Hoffmann, Kaley Blankenship, Burgess B. Freeman, Xiaofeng Wang, Andrew O. Giacomelli, Brinton Seashore-Ludlow, Pilar Ramos, Kaeli M. Mathias, Yiannis Drosos, Hsien-Chao Chou, Guillaume Kugener, Andrew L. Hong, Mariana DoCarmo, Lisa Brenan, Minh-Tam Pham, Taylor E. Arnoff, Matthew G. Rees, Elaine M. Oberlick, Thomas P. Howard
Combined supplementary figures with accompanying legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477cd833910a34100dbb7c02a3286cc0
https://doi.org/10.1158/1078-0432.22476123
https://doi.org/10.1158/1078-0432.22476123
Autor:
Yiannis Drosos, Jacquelyn A. Myers, Beisi Xu, Kaeli M. Mathias, Emma C. Beane, Sandi Radko-Juettner, Robert J. Mobley, Margaret E. Larsen, Federica Piccioni, Xiaotu Ma, Jonathan Low, Baranda S. Hansen, Samuel T. Peters, Natarajan V. Bhanu, Sandeep K. Dhanda, Taosheng Chen, Santhosh A. Upadhyaya, Shondra M. Pruett-Miller, David E. Root, Benjamin A. Garcia, Janet F. Partridge, Charles W.M. Roberts
Publikováno v:
Mol Cell
Disruption of antagonism between SWI/SNF chromatin remodelers and polycomb repressor complexes drives the formation of numerous cancer types. Recently, an inhibitor of the polycomb protein EZH2 was approved for the treatment of a sarcoma mutant in th
Autor:
Aristeidis H. Zibis, Katerina Vassiou, Yiannis Drosos, Sophia Havaki, Dimitrios L. Arvanitis, Michail Nikolaou, Leonidas D. Arvanitis, Sotirios Sotiriou
Publikováno v:
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 40(4)
Epitope H contains an O-linked N-acetylglucosamine (O-GlcNAcH) residue in a specific conformation and/or environment recognized by the mouse monoclonal antibody H. O-GlcNAcH is present in several types of cells and in several polypeptides, including
Autor:
Minh-Tam Pham, Charles W. M. Roberts, Burgess B. Freeman, Kaeli M. Mathias, Cory M. Johannessen, Thomas P. Howard, Elizabeth Stewart, Hong L. Tiv, Andrew O. Giacomelli, Pilar Ramos, Yiannis Drosos, Lisa Brenan, Prafulla C. Gokhale, Kaley Blankenship, Lauren Hoffmann, Andrew L. Hong, Hsien-Chao Chou, Brinton Seashore-Ludlow, Guillaume Kugener, William C. Hahn, Taylor E. Arnoff, Mariana DoCarmo, Stuart L. Schreiber, Elaine M. Oberlick, Matthew G. Rees, Xiaofeng Wang
Publikováno v:
Clin Cancer Res
Purpose: Rhabdoid tumors are devastating pediatric cancers in need of improved therapies. We sought to identify small molecules that exhibit in vitro and in vivo efficacy against preclinical models of rhabdoid tumor. Experimental Design: We screened
Autor:
Jerold E. Rehg, Geoffrey Neale, Emin Kuliyev, Anirban Maitra, Yiannis Drosos, M. Kay Washington, David B. Finkelstein, Jianming Ye, Beatriz Sosa-Pineda, Leena Paul, Anna L. Means
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 3, Pp 172-184 (2016)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
The current paradigm of pancreatic neoplastic transformation proposes an initial step whereby acinar cells convert into acinar-to-ductal metaplasias, followed by progression of these lesions into neoplasias under sustained oncogenic activity and infl
Autor:
Andrey Korshunov, Marina Rhyzova, Stephan Wolf, Marc Zapatka, Dominik Sturm, Charles W. M. Roberts, Andreas E. Kulozik, Amar Gajjar, Martin Hasselblatt, Jan-Philipp Mallm, Michael C. Frühwald, Peter Lichter, Katja Beck, Martina Finetti, Olaf Witt, Roland Eils, Hsien-Chao Chou, Marcel Kool, David T.W. Jones, Lukas Chavez, Pascal Johann, Paul A. Northcott, Stefan M. Pfister, Yiannis Drosos, Jan O. Korbel, Serap Erkek, Daniel Williamson
Publikováno v:
Cancer cell. 35(1)
Biallelic inactivation of SMARCB1, encoding a member of the SWI/SNF chromatin remodeling complex, is the hallmark genetic aberration of atypical teratoid rhabdoid tumors (ATRT). Here, we report how loss of SMARCB1 affects the epigenome in these tumor