Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yiangos Psaras"'
Autor:
Yiangos Psaras, Christopher N. Toepfer
Publikováno v:
Experimental Physiology, Vol 109, Iss 2, Pp 175-189 (2024)
Abstract Skeletal myopathies and ataxias with secondary cardiac involvement are complex, progressive and debilitating conditions. As life expectancy increases across these conditions, cardiac involvement often becomes more prominent. This highlights
Externí odkaz:
https://doaj.org/article/57218d158f934395890ce2163dd2b42f
Autor:
Francesca Margara, Yiangos Psaras, Zhinuo Jenny Wang, Manuel Schmid, Ruben Doste, Amanda C. Garfinkel, Giuliana G. Repetti, Jonathan G. Seidman, Christine E. Seidman, Blanca Rodriguez, Christopher N. Toepfer, Alfonso Bueno-Orovio
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Cardiomyopathies have unresolved genotype–phenotype relationships and lack disease-specific treatments. Here we provide a framework to identify genotype-specific pathomechanisms and therapeutic targets to accelerate the development of prec
Externí odkaz:
https://doaj.org/article/ef7eab18d6564aba82cb6d5fd83d09e7
Autor:
Francesca Margara, Yiangos Psaras, Zhinuo Jenny Wang, Manuel Schmid, Ruben Doste, Amanda Garfinkel, Giuliana G. Repetti, Jonathan Seidman, Christine Seidman, Blanca Rodriguez, Christopher N. Toepfer, Alfonso Bueno-Orovio
Cardiomyopathies have unresolved genotype-phenotype relationships and lack disease-specific treatments. Here we identify genotype-specific pathomechanisms and therapeutic targets combining experimental hiPSC-CM modelling and human-based cardiac elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d381a7c65fb10b735346455d1914602d
https://doi.org/10.1101/2022.06.08.495324
https://doi.org/10.1101/2022.06.08.495324
Autor:
Francesca Margara, Manuel Schmid, Amanda Garfinkel, Jonathan G. Seidman, Júlia D. C. Marsiglia, Giuliana Repetti, Violetta Steeples, Christopher N. Toepfer, Bueno-Orovio Alfonso, Christine E. Seidman, Yiangos Psaras, Blanca Rodriguez
Publikováno v:
Circulation Research. 129
Hypertrophic cardiomyopathy (HCM) affects as many as ~1 in 500 individuals, and is often typified by hyperdynamic contraction and poor cellular relaxation. HCM can be caused by mutations in a variety of key contractile proteins of the sarcomere. A la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e04379c23686d3af901f5d468ce982d
https://doi.org/10.1161/res.129.suppl_1.402
https://doi.org/10.1161/res.129.suppl_1.402
Autor:
Christopher N. Toepfer, Blanca Rodriguez, Alfonso Bueno-Orovio, Yiangos Psaras, Francesca Margara
Publikováno v:
Journal of Pharmacological and Toxicological Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af82853c61fdc0530ce938187cbc355
Autor:
Giuliana G. Repetti, Manuel Schmid, Paul Robinson, Jon A. L. Willcox, Christopher N. Toepfer, Alfonso Bueno-Orovio, Jonathan G. Seidman, Christine E. Seidman, Francesca Margara, Violetta Steeples, Marcelo Cicconet, Yiangos Psaras, Blanca Rodriguez, Charles Redwood, Alexander J Sparrow, Hugh Watkins
Publikováno v:
Circulation Research
Circulation research, vol 129, iss 2
Circulation research, vol 129, iss 2
Supplemental Digital Content is available in the text.
Rationale: Calcium transient analysis is central to understanding inherited and acquired cardiac physiology and disease. Although the development of novel calcium reporters enables assays of
Rationale: Calcium transient analysis is central to understanding inherited and acquired cardiac physiology and disease. Although the development of novel calcium reporters enables assays of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7caa84aa17acf4ecccacbe61254786e9
https://doi.org/10.1161/CIRCRESAHA.121.318868
https://doi.org/10.1161/CIRCRESAHA.121.318868
Autor:
Francesca Margara, Blanca Rodriguez, Alfonso Bueno-Orovio, Yiangos Psaras, Christopher N. Toepfer
Publikováno v:
EP Europace
Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement 764738. British Heart Foundat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a218861f7d2e8730363b81e4028810e6
Autor:
'Yiangos Psaras
Publikováno v:
Francesca Margara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::6c3ecf9051755de7a1ea91dee6b1d8c8