Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Yian Ann Chen"'
Autor:
Naomi C. Brownstein, Yian Ann Chen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Antibodies testing in the coronavirus era is frequently promoted, but the underlying statistics behind their validation has come under more scrutiny in recent weeks. We provide calculations, interpretations, and plots of positive and negativ
Externí odkaz:
https://doaj.org/article/b305edd24a86475f98c58df64eca8c51
Autor:
Shari Pilon-Thomas, Daniel Abate-Daga, Amod Sarnaik, Dongliang Du, Matthew Beatty, Renata Rossetti, Leticia Tordesillas, Yian Ann Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/3d327b5a71eb4de1b0deb2a0cff28cff
Autor:
Zachary J. Thompson, Jamie K. Teer, Jiannong Li, Zhihua Chen, Eric A. Welsh, Yonghong Zhang, Noura Ayoubi, Zeynep Eroglu, Aik Choon Tan, Keiran S. M. Smalley, Yian Ann Chen
Publikováno v:
Cells, Vol 11, Iss 18, p 2894 (2022)
Although substantial progress has been made in treating patients with advanced melanoma with targeted and immuno-therapies, de novo and acquired resistance is commonplace. After treatment failure, therapeutic options are very limited and novel strate
Externí odkaz:
https://doaj.org/article/ac45d504ae06489ea9a0020319ae808d
Autor:
Paul A. Stewart, Eric A. Welsh, Robbert J. C. Slebos, Bin Fang, Victoria Izumi, Matthew Chambers, Guolin Zhang, Ling Cen, Fredrik Pettersson, Yonghong Zhang, Zhihua Chen, Chia-Ho Cheng, Ram Thapa, Zachary Thompson, Katherine M. Fellows, Jewel M. Francis, James J. Saller, Tania Mesa, Chaomei Zhang, Sean Yoder, Gina M. DeNicola, Amer A. Beg, Theresa A. Boyle, Jamie K. Teer, Yian Ann Chen, John M. Koomen, Steven A. Eschrich, Eric B. Haura
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Squamous cell lung cancer has dismal prognosis due to the dearth of effective treatments. Here, the authors perform an integrated proteogenomic analysis of the disease, revealing three proteomics-based subtypes and suggesting potential therapeutic op
Externí odkaz:
https://doaj.org/article/841bd6d6165d4e9f8532ae0a3ce6a908
Autor:
Jae-Young Kim, Paul A. Stewart, Adam L. Borne, Bin Fang, Eric A. Welsh, Yian Ann Chen, Steven A. Eschrich, John M. Koomen, Eric B. Haura
Publikováno v:
Proteomes, Vol 4, Iss 2, p 16 (2016)
One way cancer cells can escape from targeted agents is through their ability to evade drug effects by rapidly rewiring signaling networks. Many protein classes, such as kinases and metabolic enzymes, are regulated by ATP binding and hydrolysis. We h
Externí odkaz:
https://doaj.org/article/57256ec4d482404a97ced0655e30fc7a
Autor:
Yian Ann Chen, Michael Schell, Xiuhua Zhao, Heather Cronin, Valerie Moberg, Lori McCormick, Allison Richards, Jodie Kroeger, Alberto J. Martinez, Pingyan Cheng, Bin Yu, Ragini Kudchadkar, Geoffrey Gibney, Jeffrey Weber
Gating Strategy for MDSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a33646293493acc3eb3bcdf47773880
https://doi.org/10.1158/2326-6066.22537871.v1
https://doi.org/10.1158/2326-6066.22537871.v1
Autor:
Yian Ann Chen, Michael Schell, Xiuhua Zhao, Heather Cronin, Valerie Moberg, Lori McCormick, Allison Richards, Jodie Kroeger, Alberto J. Martinez, Pingyan Cheng, Bin Yu, Ragini Kudchadkar, Geoffrey Gibney, Jeffrey Weber
Suppression of T-cell proliferation by MDSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d09f018d16c61f4fa82c6a50a599120
https://doi.org/10.1158/2326-6066.22537868.v1
https://doi.org/10.1158/2326-6066.22537868.v1
Autor:
Yian Ann Chen, Michael Schell, Xiuhua Zhao, Heather Cronin, Valerie Moberg, Lori McCormick, Allison Richards, Jodie Kroeger, Alberto J. Martinez, Pingyan Cheng, Bin Yu, Ragini Kudchadkar, Geoffrey Gibney, Jeffrey Weber
The checkpoint inhibitor nivolumab is active in patients with metastatic melanoma who have failed ipilimumab. In this phase I/II study, we assessed nivolumab's safety in 92 ipilimumab-refractory patients with unresectable stage III or IV melanoma, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7be50ee32acc2c375be484ca0085349
https://doi.org/10.1158/2326-6066.c.6548582.v1
https://doi.org/10.1158/2326-6066.c.6548582.v1
Autor:
Yian Ann Chen, Michael Schell, Xiuhua Zhao, Heather Cronin, Valerie Moberg, Lori McCormick, Allison Richards, Jodie Kroeger, Alberto J. Martinez, Pingyan Cheng, Bin Yu, Ragini Kudchadkar, Geoffrey Gibney, Jeffrey Weber
Supplementary Materials and Methods and Supplementary Table 1. This table describes the treatment characteristics of the six cohorts of patients that participated in the study described herein, including what grades of toxicity to prior ipilimumab th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef5d952fef9109a3a55d8557be540d3
https://doi.org/10.1158/2326-6066.22537874.v1
https://doi.org/10.1158/2326-6066.22537874.v1
Autor:
Paul D.P. Pharoah, Simon A. Gayther, Matthew L. Freedman, Alvaro N.A. Monteiro, Thomas A. Sellers, Argyrios Ziogas, Wei Zheng, Hannah Yang, Anna Wu, Xifeng Wu, Yin-Ling Woo, Lynne R. Wilkens, Kristine G. Wicklund, Alice S. Whittemore, Nicolas Wentzensen, Christine Walsh, Shan Wang-Gohrke, Robert A. Vierkant, Ignace Vergote, Els Van Nieuwenhuysen, Anne M. van Altena, Shelley S. Tworoger, Ya-Yu Tsai, Agnieszka Timorek, Pamela J. Thompson, Kathryn L. Terry, Soo-Hwang Teo, Ingvild L. Tangen, Lara E. Sucheston-Campbell, Melissa C. Southey, Honglin Song, Weiva Sieh, Nadeem Siddiqui, Yurii B. Shvetsov, Xiao-Ou Shu, Ira Schwaab, Joellen M. Schildkraut, Helga B. Salvesen, Iwona K. Rzepecka, Ingo B. Runnebaum, Anja Rudolph, Joseph H. Rothstein, Mary Anne Rossing, Barry Rosen, Harvey A. Risch, Susan J. Ramus, Elizabeth M. Poole, Malcolm C. Pike, Catherine M. Phelan, Jennifer Permuth-Wey, Liisa M. Pelttari, Tanja Pejovic, Celeste Leigh Pearce, Rachel Palmieri Weber, Sandra Orsulic, Irene Orlow, Sara H. Olson, Kunle Odunsi, Heli Nevanlinna, Roberta B. Ness, Lotte Nedergaard, Steven A. Narod, Kirsten B. Moysich, Francesmary Modugno, Usha Menon, Iain A. McNeish, John R. McLaughlin, Valerie McGuire, Keitaro Matsuo, Leon Massuger, Lene Lundvall, Jan Lubinski, Karen Lu, Jolanta Lissowska, Dong Liang, Douglas A. Levine, Jenny Lester, Arto Leminen, Shashi Lele, Alice W. Lee, Nhu D. Le, Sandrina Lambrechts, Diether Lambrechts, Jolanta Kupryjanczyk, Camilla Krakstad, Lambertus A. Kiemeney, Joseph Kelley, Melissa Kellar, Linda E. Kelemen, Susanne K. Kjaer, Beth Y. Karlan, Bu-Tian Ji, Allan Jensen, James Paul, Anna Jakubowska, Edwin S. Iversen, Satoyo Hosono, Claus K. Hogdall, Estrid Hogdall, Peter Hillemanns, Michelle A.T. Hildebrandt, Florian Heitz, Alexander Hein, Philipp Harter, Patricia Harrington, Jacek Grownwald, Marc T. Goodman, Ellen L. Goode, Rosalind Glasspool, Graham G. Giles, Aleksandra Gentry-Maharaj, Yu-Tang Gao, Brooke L. Fridley, Peter A. Fasching, Arif B. Ekici, Robert P. Edwards, Douglas F. Easton, Diana Eccles, Matthias Dürst, Andreas du Bois, Thilo Dörk, Jennifer A. Doherty, Ed Dicks, Joe Dennis, Agnieszka Dansonka-Mieszkowska, Cezary Cybulski, Julie M. Cunningham, Daniel Cramer, Linda S. Cook, Zhihua Chen, Yian Ann Chen, Jenny Chang-Claude, Karen Carty, Ian Campbell, Ralf Butzow, Angela Brooks-Wilson, Louise Brinton, Natalia Bogdanova, Line Bjørge, Maria Bisogna, Andrew Berchuck, Matthias W. Beckmann, Yukie T. Bean, Elisa V. Bandera, Helen Baker, Georgia Chenevix-Trench, Natalia Antonenkova, Hoda Anton-Culver, Katja K.H. Aben, Kate Lawrenson, Qiyuan Li, Jonathan P. Tyrer, Siddhartha P. Kar
Background: Genome-wide association studies (GWAS) have so far reported 12 loci associated with serous epithelial ovarian cancer (EOC) risk. We hypothesized that some of these loci function through nearby transcription factor (TF) genes and that puta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6f06831e464b5462b9d60f6e076139
https://doi.org/10.1158/1055-9965.c.6515944.v1
https://doi.org/10.1158/1055-9965.c.6515944.v1