Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Yi., Kou"'
Autor:
Claire S. Chung, Yi Kou, Sarah J. Shemtov, Bert M. Verheijen, Ilse Flores, Kayla Love, Ashley Del Dosso, Max A. Thorwald, Yuchen Liu, Daniel Hicks, Yingwo Sun, Renaldo G. Toney, Lucy Carrillo, Megan M. Nguyen, Huang Biao, Yuxin Jin, Ashley Michelle Jauregui, Juan Diaz Quiroz, Elizabeth Head, Darcie L. Moore, Stephen Simpson, Kelley W. Thomas, Marcelo P. Coba, Zhongwei Li, Bérénice A. Benayoun, Joshua J. C. Rosenthal, Scott R. Kennedy, Giorgia Quadrato, Jean-Francois Gout, Lin Chen, Marc Vermulst
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Aging is characterized by the accumulation of proteins that display amyloid-like behavior. However, the molecular mechanisms by which these proteins arise remain unclear. Here, we demonstrate that amyloid-like proteins are produced in a vari
Externí odkaz:
https://doaj.org/article/bc97abb49e574bb98ff14f78f00de4cf
Autor:
Hye Yeon Choi, Yicheng Zhu, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M. Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 461-477 (2024)
Abstract The P53-destabilizing TBC1D15-NOTCH protein interaction promotes self-renewal of tumor-initiating stem-like cells (TICs); however, the mechanisms governing the regulation of this pathway have not been fully elucidated. Here, we show that TBC
Externí odkaz:
https://doaj.org/article/cce91a31632d430a830e45249520ef25
Autor:
Hye Yeon Choi, Yicheng Zhu, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M. Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 10, Pp 2323-2323 (2024)
Externí odkaz:
https://doaj.org/article/15ad0b71720f4c6c94a3eda7ed45a7d3
Autor:
Da-Wei Yeh, Xuyao Zhao, Hifzur R. Siddique, Mengmei Zheng, Hye Yeon Choi, Tatsuya Machida, Padmini Narayanan, Yi Kou, Vasu Punj, Stanley M. Tahara, Douglas E. Feldman, Lin Chen, Keigo Machida
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract RNA-binding protein Musashi 2 (MSI2) is elevated in several cancers and is linked to poor prognosis. Here, we tested if MSI2 promotes MYC and viral mRNA translation to induce self-renewal via an internal ribosome entry sequence (IRES). We pe
Externí odkaz:
https://doaj.org/article/f53b059996d14f06981134f03c1b966e
Publikováno v:
Journal of Marine Science and Engineering, Vol 11, Iss 11, p 2177 (2023)
In the context of climate change with frequent natural disasters, disaster risk assessment can provide great help for related risk decision-making. Based on the theory of loss expectation, this paper presents a quantitative method to assess typhoon d
Externí odkaz:
https://doaj.org/article/4cb12dc652b5420f871d7888e177dea8
Autor:
Baiyu Chen, Yi Kou, Yufeng Wang, Daniel Zhao, Shaoxun Liu, Guilin Liu, Liping Wang, Xuefeng Han
Publikováno v:
AIMS Mathematics, Vol 6, Iss 2, Pp 1177-1190 (2021)
Most of the offshore projects will be impacted by storm surge, especially in the sea area where typhoons are frequent, and storm surge disasters are inevitable. The establishment of a theoretical distribution model of the number of typhoon occurrence
Externí odkaz:
https://doaj.org/article/dc330fc62b47491aa9e1dac5a4286e44
Autor:
Hye Yeon Choi, Hifzur R. Siddique, Mengmei Zheng, Yi Kou, Da-Wei Yeh, Tatsuya Machida, Chia-Lin Chen, Dinesh Babu Uthaya Kumar, Vasu Punj, Peleg Winer, Alejandro Pita, Linda Sher, Stanley M. Tahara, Ratna B. Ray, Chengyu Liang, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Normal stem cells are maintained by asymmetric cell division, but this process is dysregulated in tumour initiating stem-like cells (TICs). Here, the authors show that TBC1D15 impairs the asymmetric division machinery and activates NOTCH pathway for
Externí odkaz:
https://doaj.org/article/b860fba9de8448de8c15f0811ec7cae9
Publikováno v:
Biochemical Journal. 480:573-585
Various alkylating agents are known to preferentially modify guanine in DNA, resulting in the formation of N7-alkylguanine (N7-alkylG) and the imidazole ring opened alkyl-formamidopyrimidine (alkyl-FapyG) lesions. Evaluating the mutagenic effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4381010c60d3c8643a4e5c544396972f
https://doi.org/10.1042/bcj20220460
https://doi.org/10.1042/bcj20220460
Publikováno v:
Information Sciences. 624:299-323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6091a9be365f37f7cb636dee355f338
https://doi.org/10.1016/j.ins.2022.12.070
https://doi.org/10.1016/j.ins.2022.12.070
Publikováno v:
Soft Computing. 27:7679-7697
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dce42ecfbbe56c18fa882094c417c83
https://doi.org/10.1007/s00500-023-08024-z
https://doi.org/10.1007/s00500-023-08024-z