Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Yi-li Min"'
Autor:
Dileep R. Karri, Yu Zhang, Francesco Chemello, Yi-Li Min, Jian Huang, Jiwoong Kim, Pradeep P.A. Mammen, Lin Xu, Ning Liu, Rhonda Bassel-Duby, Eric N. Olson
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 154-167 (2022)
Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by mutations in the dystrophin gene. CRISPR/Cas9 genome editing has been used to correct DMD mutations in animal models at young ages. However, the longevity and durability of CRISPR
Externí odkaz:
https://doaj.org/article/b43ce09cc0a3454181205c248f318e1a
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Therapeutic targets of CRISPR-Cas can often not be accessed due to lack of carriers to deliver RNPs systematically. Here, the authors engineer modified lipid nanoparticles for delivery of gene editing proteins to specific tissues.
Externí odkaz:
https://doaj.org/article/643f6e049bbd4fa2a9c4925cf329f370
Autor:
Leonela Amoasii, Hui Li, Yu Zhang, Yi-Li Min, Efrain Sanchez-Ortiz, John M. Shelton, Chengzu Long, Alex A. Mireault, Samadrita Bhattacharyya, John R. McAnally, Rhonda Bassel-Duby, Eric N. Olson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Dystrophin-deficient mice are used to test corrective strategies for Duchenne muscular dystrophy, but evaluation of dystrophin expression requires collection of tissue samples from specific muscles and time points. Here, the authors generate mice in
Externí odkaz:
https://doaj.org/article/3998bffcfb4f49da8616481acc9f1799
Autor:
Cheng-Der Liu, Ya-Lin Chen, Yi-Li Min, Bo Zhao, Chi-Ping Cheng, Myung-Soo Kang, Shu-Jun Chiu, Elliott Kieff, Chih-Wen Peng
Publikováno v:
PLoS Pathogens, Vol 8, Iss 12, p e1003084 (2012)
Epstein-Barr Virus (EBV) is an oncogenic γ-herpesvirus that capably establishes both latent and lytic modes of infection in host cells and causes malignant diseases in humans. Nuclear antigen 2 (EBNA2)-mediated transcription of both cellular and vir
Externí odkaz:
https://doaj.org/article/440aed0c64514d2381c380b084d6b62a
97
Transcriptions of specific viral promoters and cellular genes driven by Epstein-Barr Virus (EBV) nuclear antigen 2 (EBNA2) and leader protein (LP) are essential for immortalization of B lymphocytes upon EBV infection. In particular, EBNA2 act
Transcriptions of specific viral promoters and cellular genes driven by Epstein-Barr Virus (EBV) nuclear antigen 2 (EBNA2) and leader protein (LP) are essential for immortalization of B lymphocytes upon EBV infection. In particular, EBNA2 act
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/09774113002702003040
Autor:
Dileep R. Karri, Yu Zhang, Francesco Chemello, Yi-Li Min, Jian Huang, Jiwoong Kim, Pradeep P.A. Mammen, Lin Xu, Ning Liu, Rhonda Bassel-Duby, Eric N. Olson
Publikováno v:
Molecular therapy. Nucleic acids. 28
Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by mutations in the dystrophin gene. CRISPR/Cas9 genome editing has been used to correct DMD mutations in animal models at young ages. However, the longevity and durability of CRISPR
Publikováno v:
Journal of Web Engineering.
With the rapid development of the Internet era, cell phones play an essential and indispensable role in nowadays life. Smartphones have profoundly influenced our social relationships and our daily lives. Generally speaking, the most common tools we h
Akademický článek
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Autor:
Alex A. Mireault, Rhonda Bassel-Duby, Yi Li Min, Yu Zhang, Hui Li, Eric N. Olson, John R. McAnally, Francesco Chemello, Cristina Rodriguez-Caycedo, John M. Shelton, Efrain Sanchez-Ortiz
Publikováno v:
Mol Ther
Duchenne muscular dystrophy (DMD), one of the most common neuromuscular disorders of children, is caused by the absence of dystrophin protein in striated muscle. Deletions of exons 43, 45, and 52 represent mutational "hotspot" regions in the dystroph
Akademický článek
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