Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yi-kun Lou"'
Publikováno v:
Journal of Hypertension. 16:1009-1014
Objective To test the hypothesis that insulin resistance of the spontaneously hypertensive rat (SHR) and adrenocorticotropin -hypertensive rat is related to a difference in the proportion of the functionally different, alternatively spliced exon 11 i
Publikováno v:
Hypertension. 26:656-664
Abstract To determine responses in renin gene expression in different tissues of two-kidney, one clip hypertensive Sprague-Dawley rats and the effect of NaCl loading, we developed a novel, highly sensitive quantitative polymerase chain reaction techn
Publikováno v:
Hypertension Research. 16:113-120
The present study examined polymorphisms of genes that might be involved in the onset of essential hypertension (HT). These included the (i) growth hormone gene (GH1), whose locus has recently been linked to elevated blood pressure (BP) in the stroke
Publikováno v:
Biochemical and Biophysical Research Communications. 184:9-15
Angiotensin I-converting enzyme (ACE) is responsible for production of angiotensin II and breakdown of kinins, leading to increased blood pressure (BP). Furthermore, ACE inhibitors are effective antihypertensive agents. A 287 bp insertion/deletion po
Autor:
Feng Yang, David J. Adams, Judith A. Whitworth, Min-Xia Wang, Yi-kun Lou, Brian J. Morris, Ming Li, Cheng Wen
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 37(4)
Abstract —Administration of adrenocorticotropic hormone (ACTH) leads to the development of hypertension. Because glucocorticoids can affect the nitric oxide system at several sites, the present study tested the hypothesis that nitric oxide synthase
Publikováno v:
Clinical and experimental pharmacologyphysiology. 23(6-7)
SUMMARY 1. There are two functionally different isoforms of the insulin receptor in humans and rats. We hypothesized that a change in their relative proportion could be of relevance to insulin resistance in hypertension. 2. A reverse-transcriptase po
Publikováno v:
Journal of virological methods. 44(1)
Sample preparation is an important step in the detection of viral DNA by the polymerase chain reaction (PCR) technique. The method used should achieve release of cellular DNA with the minimum of manipulation steps so as to reduce the possibility of c
Publikováno v:
Journal of hypertension. 11(3)
OBJECTIVE The aim of the present study was to use a highly sensitive, polymerase chain reaction (PCR) technique to examine the controversial question of renin gene expression in the heart and to determine whether expression in cardiac tissue can be s
Publikováno v:
Lancet (London, England). 338(8782-8783)
Publikováno v:
Clinical and experimental pharmacologyphysiology. 18(5)
SUMMARY 1. Renin mRNA is present in the kidney and, in lower concentrations, in many extrarenal tissues and serves as an index of renin gene activity, as well as potential renin or prorenin synthesis in cell populations within those tissues. Unfortun