Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Yi-guang Chen"'
Autor:
Xiao-ting XIONG, Pu RAO, Chun-sheng LIU, Yi-guang CHEN, Zi-feng SONG, Chun LIN, Hui-yong LI, Xiao-gang HUANG, Guo-shan HE
Publikováno v:
Zhipu Xuebao, Vol 45, Iss 4, Pp 577-586 (2024)
Photointiators have been commercially applied in ultra-violet photocuring ink, varnish, coating, lacquers since 1970s. The significant advantages of efficient, energy-saving and environmental-friendly make them more and more popular in automobile ind
Externí odkaz:
https://doaj.org/article/12287047e3f4482d83a3f2189d6b3ef3
Autor:
Achia Khatun, Xiaopeng Wu, Fu Qi, Kexin Gai, Arjun Kharel, Matthew R. Kudek, Lisa Fraser, Ashley Ceicko, Moujtaba Y. Kasmani, Amber Majnik, Robert Burns, Yi‐Guang Chen, Nita Salzman, Elizabeth J. Taparowsky, Dayu Fang, Calvin B. Williams, Weiguo Cui
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract Regulatory T (Treg) cells are inevitable to prevent deleterious immune responses to self and commensal microorganisms. Treg function requires continuous expression of the transcription factor (TF) FOXP3 and is divided into two major subsets:
Externí odkaz:
https://doaj.org/article/786eb5c93e3443a6b323cd0698684eb8
Autor:
Susanne M. Cabrera, Alison T. Coren, Tarun Pant, Ashley E. Ciecko, Shuang Jia, Mark F. Roethle, Pippa M. Simpson, Samantha N. Atkinson, Nita H. Salzman, Yi-Guang Chen, Martin J. Hessner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The incidence of type 1 diabetes (T1D) has increased, coinciding with lifestyle changes that have likely altered the gut microbiota. Dysbiosis, gut barrier dysfunction, and elevated systemic inflammation consistent with microbial antigen exp
Externí odkaz:
https://doaj.org/article/ad250eba8213477aa74556a077af8614
Autor:
Samuel I. Blum, Jared P. Taylor, Jessie M. Barra, Ashley R. Burg, Qiao Shang, Shihong Qiu, Oren Shechter, Aleah R. Hayes, Todd J. Green, Aron M. Geurts, Yi-Guang Chen, Hubert M. Tse
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Type 1 diabetes (T1D) is an autoimmune disease resulting in pancreatic β cell destruction. Coxsackievirus B3 (CVB3) infection and melanoma differentiation-associated protein 5–dependent (MDA5-dependent) antiviral responses are linked with T1D deve
Externí odkaz:
https://doaj.org/article/481ea67a6fde4ec79a6074eb8b6ff38c
Autor:
Pinar Sargin, Mark F. Roethle, Shuang Jia, Tarun Pant, Ashley E. Ciecko, Samantha N. Atkinson, Nita H. Salzman, Ru-Jeng Teng, Yi-Guang Chen, Susanne M. Cabrera, Martin J. Hessner
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The increasing incidence of Type 1 diabetes has coincided with the emergence of the low-fiber, high-gluten Western diet and other environmental factors linked to dysbiosis. Since Lactiplantibacillus plantarum 299 v (Lp299v) supplementation improves g
Externí odkaz:
https://doaj.org/article/04e49acff871446096d9b0058aa801e5
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f7e21a43f9d84f5db260f1ece2729cff
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Autoimmunity involves a loss of immune tolerance to self-proteins due to a combination of genetic susceptibility and environmental provocation, which generates autoreactive T and B cells. Genetic susceptibility affects lymphocyte autoreactivity at th
Externí odkaz:
https://doaj.org/article/770f4d98dcac44a3ab56512b76e0240f
Autor:
Melanie R. Shapiro, Wen-I Yeh, Joshua R. Longfield, John Gallagher, Caridad M. Infante, Sarah Wellford, Amanda L. Posgai, Mark A. Atkinson, Martha Campbell-Thompson, Scott M. Lieberman, David V. Serreze, Aron M. Geurts, Yi-Guang Chen, Todd M. Brusko
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The costimulatory molecule CD226 is highly expressed on effector/memory T cells and natural killer cells. Costimulatory signals received by T cells can impact both central and peripheral tolerance mechanisms. Genetic polymorphisms in CD226 have been
Externí odkaz:
https://doaj.org/article/7bccfa348d184824bd0a2ddaebeab0f9
Autor:
Ashley E. Ciecko, Bardees Foda, Jennifer Y. Barr, Sheela Ramanathan, Mark A. Atkinson, David V. Serreze, Aron M. Geurts, Scott M. Lieberman, Yi-Guang Chen
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3073-3086.e5 (2019)
Summary: Human genetic studies implicate interleukin-27 (IL-27) in the pathogenesis of type 1 diabetes (T1D), but the underlying mechanisms remain largely unexplored. To further define the role of IL-27 in T1D, we generated non-obese diabetic (NOD) m
Externí odkaz:
https://doaj.org/article/3fc24c0010584feaa74f430e920e1248
Autor:
Arata Itoh, Lorenzo Ortiz, Kritika Kachapati, Yuehong Wu, David Adams, Kyle Bednar, Shibabrata Mukherjee, Claire Chougnet, Robert S. Mittler, Yi-Guang Chen, Laurence Dolan, William M. Ridgway
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
We show here that soluble CD137 (sCD137), the alternately spliced gene product of Tnfsfr9, effectively treats acute type 1 diabetes (T1D) in nonobese diabetic (NOD) mice. sCD137 significantly delayed development of end-stage disease, preserved insuli
Externí odkaz:
https://doaj.org/article/a1f4bc23defc4c90872138307eddea17