Zobrazeno 1 - 10
of 449
pro vyhledávání: '"Yi-Zhun Zhu"'
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/96a36a8459fc4187b8218f2b03611944
Publikováno v:
Pharmacological Research, Vol 201, Iss , Pp 107100- (2024)
The development of natural products for potential new drugs faces obstacles such as unknown mechanisms, poor solubility, and limited bioavailability, which limit the broadened applicability of natural products. Therefore, there is a need for advanced
Externí odkaz:
https://doaj.org/article/9b623a52b4064626bd52f2a3894a0ad6
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 958 (2024)
The balanced crosstalk between miRNAs and autophagy is essential in hypertensive nephropathy. Hydrogen sulfide donors have been reported to attenuate renal injury, but the mechanism is unclear. We aimed to identify and verify the miRNAs and autophagy
Externí odkaz:
https://doaj.org/article/b8f005118b0e4cdbb7057d06e85433a5
Autor:
Qinyan Yang, Yiran Zhao, Na Li, Jian-Lin Wu, Xiaolun Huang, Mei Zhang, Xiqing Bian, Yi-Zhun Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Osteoarthritis (OA) is a prevalent joint disorder worldwide. Sodium hyaluronate (SH) and mesenchymal stem cells (MSCs) are promising therapeutic strategies for OA. Previous studies showed they could improve knee function and clinical sy
Externí odkaz:
https://doaj.org/article/f1b10d78c06241008a4c9442c9edb900
Autor:
Dong-Dong Wu, Sheng Jin, Ruo-Xiao Cheng, Wen-Jie Cai, Wen-Long Xue, Qing-Qing Zhang, Le-Jie Yang, Qi Zhu, Meng-Yao Li, Ge Lin, Yi-Zhen Wang, Xue-Pan Mu, Yu Wang, Igor Ying Zhang, Qi Zhang, Ying Chen, Sheng-Yang Cai, Bo Tan, Ye Li, Yun-Qian Chen, Pu-Juan Zhang, Chen Sun, Yue Yin, Ming-Jie Wang, Yi-Zhun Zhu, Bei-Bei Tao, Jia-Hai Zhou, Wei-Xue Huang, Yi-Chun Zhu
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112750- (2023)
Summary: The present study examines whether there is a mechanism beyond the current concept of post-translational modifications to regulate the function of a protein. A small gas molecule, hydrogen sulfide (H2S), was found to bind at active-site copp
Externí odkaz:
https://doaj.org/article/4f5a5fbce8904261a2dd86229256dcdb
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/e1c5d29fa5324ad5bf5c9f54d5b05e30
Autor:
Yi-Kong Lin, Yun-Yun Li, Yue Li, Da-Jin Li, Xiao-Lin Wang, Li Wang, Min Yu, Yi-Zhun Zhu, Jia-Jing Cheng, Mei-Rong Du
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundEndometriosis (EMS), an endocrine-related inflammatory disease, is characterized by estrogen and progesterone imbalance in ectopic lesions. However, its pathogenic mechanism has not been fully elucidated. While SCM-198 is the synthetic form
Externí odkaz:
https://doaj.org/article/4af00718c77344e2acda493fd6213975
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 908 (2023)
Mammalian cells and tissues have the capacity to generate hydrogen sulfide gas (H2S) via catabolic routes involving cysteine metabolism. H2S acts on cell signaling cascades that are necessary in many biochemical and physiological roles important in t
Externí odkaz:
https://doaj.org/article/724fd50ef2494d61823b0374594bd27f
Autor:
He-Ping Lei, Min Qin, Li-Yun Cai, Hong Wu, Lan Tang, Ju-E Liu, Chun-Yu Deng, Yi-Bin Liu, Qian Zhu, Han-Ping Li, Wei Hu, Min Yang, Yi-Zhun Zhu, Shi-Long Zhong
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
It is widely accepted that genetic polymorphisms impact atorvastatin (ATV) metabolism, clinical efficacy, and adverse events. The objectives of this study were to identify novel genetic variants influencing ATV metabolism and outcomes in Chinese pati
Externí odkaz:
https://doaj.org/article/92983670d3ce4691bb2cfc11418a814f
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Myocardial ischemic injury is among the top 10 leading causes of death from cardiovascular diseases worldwide. Myocardial ischemia is caused mainly by coronary artery occlusion or obstruction. It usually occurs when the heart is insufficiently perfus
Externí odkaz:
https://doaj.org/article/fae7ac7e496c4014a3895637b45b8d22