Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Yi-Xin Huo"'
Autor:
Zhenya Chen, Shengzhu Yu, Jing Liu, Liwei Guo, Tong Wu, Peifeng Duan, Dongli Yan, Chaoyong Huang, Yi‐Xin Huo
Publikováno v:
Advanced Science, Vol 11, Iss 23, Pp n/a-n/a (2024)
Abstract Microbial factories lacking the ability of dynamically regulating the pathway enzymes overexpression, according to in situ metabolite concentrations, are suboptimal, especially when the metabolic intermediates are competed by growth and chem
Externí odkaz:
https://doaj.org/article/89dad004c6da441ba52893b46de9c81e
Autor:
Zeyu Liang, Chaoyong Huang, Yan Xia, Zhaojin Ye, Shunhua Fan, Junwei Zeng, Shuyuan Guo, Xiaoyan Ma, Lichao Sun, Yi-Xin Huo
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114290- (2024)
Summary: Coexpressing multiple identical single guide RNAs (sgRNAs) in CRISPR-dependent engineering triggers genetic instability and phenotype loss. To provide sgRNA derivatives for efficient DNA digestion, we design a high-throughput digestion-activ
Externí odkaz:
https://doaj.org/article/27c3bd75c8fc416b9e2e426bb462d166
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Vanillin (4-hydroxy-3-methoxybenzaldehyde) is one of the most popular flavors with wide applications in food, fragrance, and pharmaceutical industries. However, the high cost and limited yield of plant extraction failed to meet the vast mark
Externí odkaz:
https://doaj.org/article/2e330d21ed6442a99f5e6ff56054cc62
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract Oxo chemicals are valuable chemicals for synthesizing a wide array of industrial and consumer products. However, producing of oxo chemicals is predominately through the chemical process called hydroformylation, which requires petroleum-sourc
Externí odkaz:
https://doaj.org/article/c71ad67a59224a7e961b492c4a0814ec
Publikováno v:
Engineering Microbiology, Vol 3, Iss 1, Pp 100066- (2023)
Microbial fermentation has contributed to 80% of global amino acid production. The key to microbial fermentation is to obtain fermentation strains with high performance to produce target amino acids with a high yield. These strains are primarily deri
Externí odkaz:
https://doaj.org/article/8fe54cf8066f4a4eb6f6cc2909d45500
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Branched chain amino acids (BCAAs) are widely applied in the food, pharmaceutical, and animal feed industries. Traditional chemical synthetic and enzymatic BCAAs production in vitro has been hampered by expensive raw materials, ha
Externí odkaz:
https://doaj.org/article/17eb0d0fdd074d93bac46c445cb48c9f
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
For decades, lignocellulosic biomass has been introduced to the public as the most important raw material for the environmentally and economically sustainable production of high-valued bioproducts by microorganisms. However, due to the strong recalci
Externí odkaz:
https://doaj.org/article/e65b03f3f7044210aaf720a030b04dde
Publikováno v:
Synthetic and Systems Biotechnology, Vol 5, Iss 4, Pp 333-342 (2020)
Escherichia coli strain K-12 MG1655 has been proposed as an appropriate host strain for industrial production. However, the direct application of this strain suffers from the transformation inefficiency and plasmid instability. Herein, we conducted g
Externí odkaz:
https://doaj.org/article/0b5bad11837e4166b4f1a9ac4eda0c78
Autor:
Yuhui Du, Wei Song, Zhiqiu Yin, Shengbo Wu, Jiaheng Liu, Ning Wang, Hua Jin, Jianjun Qiao, Yi-Xin Huo
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Azadirachta indica (neem), an evergreen tree of the Meliaceae family, is a source of the potent biopesticide azadirachtin. The lack of a chromosome-level assembly impedes an in-depth understanding of its genome architecture and the comparative genomi
Externí odkaz:
https://doaj.org/article/25ee1f2f1dd246328e0a81c3f46f2184
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-13 (2020)
Abstract Background Co-expression of two distinct guide RNAs (gRNAs) has been used to facilitate the application of CRISPR/Cas9 system in fields such as large genomic deletion. The paired gRNAs are often placed adjacently in the same direction and ex
Externí odkaz:
https://doaj.org/article/ffbd8a1b005b424fb2074e3d5458eb2e