Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yi-Xiang Hong"'
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Background Angiogenesis is critical for forming new blood vessels from antedating vascular vessels. The endothelium is essential for angiogenesis, vascular remodelling and minimisation of functional deficits following ischaemia. The insulin
Externí odkaz:
https://doaj.org/article/4b70606772b24902a85b33668421d143
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract N-methyl-D-aspartate receptors (NMDARs) are ligand-gated, voltage-dependent channels of the ionotropic glutamate receptor family. The present study explored whether NMDAR activation induced ferroptosis in vascular endothelial cells and its c
Externí odkaz:
https://doaj.org/article/5bf53c37e7a740149b7e01a1b02f429e
Autor:
Wei-Min Han, Xiao-Bin Hao, Yi-Xiang Hong, Shan-Shan Zhao, Xu-Chang Chen, Ruiying Wang, Yan Wang, Gang Li
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Lipopolysaccharide (LPS) displays a robust immunostimulatory ability upon Toll-like receptor 4 (TLR4) recognition. N-methyl-D-aspartate receptors (NMDARs) are highly compartmentalized in most cells and implicated in various inflammatory diso
Externí odkaz:
https://doaj.org/article/0fc4cbe3d0864748a3eb72dd561cf2fd
Autor:
Liang Mao, Yun-Da Li, Ruo-Lan Chen, Gang Li, Xiao-Xia Zhou, Fei Song, Chan Wu, Yu Hu, Yi-Xiang Hong, Xitong Dang, Gui-Rong Li, Yan Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Exosomes of human cardiosphere-derived cells (CDCs) are very promising for treating cardiovascular disorders. However, the current challenge is inconvenient delivery methods of exosomes for clinical application. The present study aims to exp
Externí odkaz:
https://doaj.org/article/a7d5fd3eaa9442c286ceedb7755cdf52
Autor:
Wei-Yin Wu, Yun-Da Li, Yu-Kai Cui, Chan Wu, Yi-Xiang Hong, Gang Li, Yao Wu, Ling-Jun Jie, Yan Wang, Gui-Rong Li
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The present study investigates the potential signal pathway of acacetin in cardioprotection against ischemia/reperfusion injury using an in vitro hypoxia/reoxygenation model in primary cultured neonatal rat cardiomyocytes and H9C2 cardiomyoblasts. It
Externí odkaz:
https://doaj.org/article/87088f25ed084a4ba07897bd497c5399
Publikováno v:
Aging (Albany NY)
Cardiac senescence is associated with cardiomyopathy which is a degenerative disease in the aging process of the elderly. The present study investigates using multiple experimental approaches whether the natural flavone acacetin could attenuate myoca
Publikováno v:
Journal of Cellular and Molecular Medicine
Doxorubicin cardiotoxicity is frequently reported in patients undergoing chemotherapy. The present study investigates whether cardiomyopathy induced by doxorubicin can be improved by the natural flavone acacetin in a mouse model and uncovers the pote
Publikováno v:
Heart Failure Reviews. 27:369-377
Heart failure is a growing health problem resulting in the decreased life expectancy of patients and severely increased the healthcare burden. Penetrating research on the pathogenesis and regulation mechanism of heart failure is important for treatme
Publikováno v:
European journal of pharmacology. 920
Cardiac hypertrophy is a major risk factor for developing heart failure. This study investigates the effects of the natural flavone acacetin on myocardial hypertrophy in cellular level and whole animals. In cardiomyocytes from neonatal rat with hyper
Autor:
Yun-Da Li, Yan Wang, Yu-Kai Cui, Wei-Yin Wu, Yi-Xiang Hong, Jing-Zhou Li, Weimin Han, Gang Li, Yao Wu, Ishan Lakhani, Fei Song
Publikováno v:
Journal of Cellular and Molecular Medicine
Oxidative stress has a considerable influence on endothelial cell dysfunction and atherosclerosis. Acacetin, an anti‐inflammatory and antiarrhythmic, is frequently used in the treatment of myocarditis, albeit its role in managing atherosclerosis is