Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yi-Tsung Liu"'
Autor:
Yi-Tsung Liu, 劉乙宗
96
This thesis focuses on the kinematics and configuration analysis of 3-PRRRR type pure translational parallel manipulator (TPM), which was proposed by Lee and Hervé [1]. Starting with the kinematic structural analysis of this kind of TPM, we
This thesis focuses on the kinematics and configuration analysis of 3-PRRRR type pure translational parallel manipulator (TPM), which was proposed by Lee and Hervé [1]. Starting with the kinematic structural analysis of this kind of TPM, we
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/64340867573580229809
Autor:
Nanhua Yao, Lata Ramanathan, Kevin X. Chen, Thierry O. Fischmann, Andrew Prongay, Corey Strickland, Mary M. Senior, Raymond G. Lovey, Richard N. Ingram, Bruce A. Malcolm, Viyyoor M. Girijavallabhan, Frank Bennett, Patricia C. Weber, Taisa Yarosh-Tomaine, John Pichardo, Anil K. Saksena, F. George Njoroge, Rong-Sheng Yang, Zhuyan Guo, Zhi Hong, Stephane L. Bogen, Srikanth Venkatraman, Ashok Arasappan, S. Shane Taremi, Brian M. Beyer, Rumin Zhang, Vincent Madison, Edwin Jao, Winifred W. Prosise, Yi-Tsung Liu, Joseph E. Myers
Publikováno v:
Journal of Medicinal Chemistry. 50:2310-2318
The structures of both the native holo-HCV NS3/4A protease domain and the protease domain with a serine 139 to alanine (S139A) mutation were solved to high resolution. Subsequently, structures were...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12ac27152dd419adc5be903b98a4f491
https://doi.org/10.1021/jm060173k
https://doi.org/10.1021/jm060173k
Autor:
Weidong Pan, Prudence Bradley, Kevin X. Chen, Parekh Tejal N, Andrea Hart, Frank Bennett, Danial Prelusky, Srikanth Venkatraman, Robert Chase, Susan Bogdanowich-Knipp, Jianshe Kong, Bancha Vibulbhan, Viyyoor M. Girijavallabhan, Hendrata Siska, Rong Kong, Weiying Yang, Kuo-Chi Cheng, Ashit K. Ganguly, Nancy Butkiewicz, Ashok Arasappan, Yuhua Huang, Andrew Prongay, Bruce A. Malcolm, Xiang Liang, Rong Liu, Xiaoming Cui, Walter A. Korfmacher, Sony Agrawal, Wanli Wu, Zhuyan Guo, Stephane L. Bogen, Pike Russell E, Ronald E. White, Jesse Wong, Yi-Tsung Liu, Jean-Marc Brisson, John Pichardo, Anil K. Saksena, Pavlovsky Anastasia, Bahige M. Baroudy, F. George Njoroge, Vincent Madison, Patrick Pinto, Santhanam Bama, Raymond G. Lovey, Edwin Jao, Lisa Broske, Veljko Popov, Yunsheng Hsieh, Paul Ingravallo, Sumei Ruan, Piwinski John J
Publikováno v:
Journal of Medicinal Chemistry. 49:6074-6086
Hepatitis C virus (HCV) infection is the major cause of chronic liver disease, leading to cirrhosis and hepatocellular carcinoma, which affects more than 170 million people worldwide. Currently the only therapeutic regimens are subcutaneous interfero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b1025f20fc929de7fcc2e4ce1f01669
https://doi.org/10.1021/jm060325b
https://doi.org/10.1021/jm060325b
Autor:
Odile E. Levy, Susan Y. Tamura, Andrew Prongay, Robert Chase, Sumei Ruan, Rong Liu, Bahige Baroudy, Paul Ingravallo, Kemp Scott Jeffrey, Viyyoor Girijavallabhan, Kevin Chen, John Pichardo, Bennett Frank, Tony Y. Hsieh, F. George Njoroge, Weidong Pan, Raymond G. Lovey, Kuo-Chi Cheng, Ashok Arasappan, Edwin Jao, Lim-Wilby Marguerita, Jean-Marc Brisson, Tajel Parekh, Russel E. Pike, Srikanth Venkatraman, Stephane L. Bogen, Sony Agrawal, Yi-Tsung Liu, Anil K. Saksena
Publikováno v:
Journal of Medicinal Chemistry. 49:2750-2757
Introduction of various modified prolines at P(2) and optimization of the P(1) side chain led to the discovery of SCH6 (24, Table 2), a potent ketoamide inhibitor of the HCV NS3 serine protease. In addition to excellent enzyme potency (K(i)*= 3.8 nM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3d177beeb1725aa51e250b5f8f869a
https://doi.org/10.1021/jm060077j
https://doi.org/10.1021/jm060077j
Autor:
Viyyoor M. Girijavallabhan, Anil K. Saksena, Jesse Wong, Mousumi Sannigrahi, Yi-Tsung Liu, Meng Tao, Rebecca Osterman
Publikováno v:
Tetrahedron Letters. 45:6097-6100
In the presence of a carboxyl group positioned for participation, NaBH(OAc) 3 will reduce the usually unreactive ketones in a stereoselective manner. This reaction was applied in a key step to prepare precursors 7 and 15 toward the title compounds 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d948c09a526e4da6aa94b4dec728c90e
https://doi.org/10.1016/j.tetlet.2004.06.070
https://doi.org/10.1016/j.tetlet.2004.06.070
Autor:
A.K. Ganguly, Taveras Arthur G, Mark E. Snow, Doll Ronald J, J. del Rosario, Larry Heimark, Birendra N. Pramanik, Bancha Vibulbhan, Yu-Sen Wang, Joan E. Brown, V. Girijavallabhan, Stephen D. Liberles, D. Cesarz, Yi-Tsung Liu, Paul Kirschmeier, Eric C. Huang, Stacy W. Remiszewski, Anthony Tsarbopoulos, Linda James
Publikováno v:
Bioorganic & Medicinal Chemistry. 5:817-820
MS based methodology employing electrospray ionization (ESI) is described for the detection of ternary complexes in which SCH 54292 or SCH 54341 and GDP are noncovalently bound to oncogenic ras protein. The observed molecular weights of 19,816 and 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ea2df6aa8d22fee8b96fd52db08e80
https://doi.org/10.1016/s0968-0896(97)00021-7
https://doi.org/10.1016/s0968-0896(97)00021-7
Autor:
Frank Bennett, Larry Heimark, Viyyoor M. Girijavallabhan, Yi-Tsung Liu, Paul McNamara, Ashit K. Ganguly, Anthony Cacciapuoti, Roberta S. Hare, Anil K. Saksena, Haiyan Wang, Cecil B. Pickett, David Loebenberg, Maryjane Hilbert, Russell E. Pike, Peter L. Bartner, George H. Miller, J. Veals, Birendra N. Pramanik, Walter A. Korfmacher, Raymond G. Lovey, Chin-Chung Lin, Pramila Kumari, Amin A. Nomeir
Publikováno v:
Journal of mass spectrometry : JMS. 43(4)
Posaconazole (SCH 56592) is a novel triazole antifungal drug that is marketed in Europe and the United States under the trade name 'Noxafil' for prophylaxis against invasive fungal infections. SCH 56592 was discovered as a possible active metabolite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56152849495e17b3f204865fe6db7f1c
https://pubmed.ncbi.nlm.nih.gov/18059003
https://pubmed.ncbi.nlm.nih.gov/18059003
Autor:
Andrew J, Prongay, Zhuyan, Guo, Nanhua, Yao, John, Pichardo, Thierry, Fischmann, Corey, Strickland, Joseph, Myers, Patricia C, Weber, Brian M, Beyer, Richard, Ingram, Zhi, Hong, Winifred W, Prosise, Lata, Ramanathan, S Shane, Taremi, Taisa, Yarosh-Tomaine, Rumin, Zhang, Mary, Senior, Rong-Sheng, Yang, Bruce, Malcolm, Ashok, Arasappan, Frank, Bennett, Stephane L, Bogen, Kevin, Chen, Edwin, Jao, Yi-Tsung, Liu, Raymond G, Lovey, Anil K, Saksena, Srikanth, Venkatraman, Viyyoor, Girijavallabhan, F George, Njoroge, Vincent, Madison
Publikováno v:
Journal of medicinal chemistry. 50(10)
The structures of both the native holo-HCV NS3/4A protease domain and the protease domain with a serine 139 to alanine (S139A) mutation were solved to high resolution. Subsequently, structures were determined for a series of ketoamide inhibitors in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b2f3225ce5710e98074c598f37ca1e4
https://pubmed.ncbi.nlm.nih.gov/17444623
https://pubmed.ncbi.nlm.nih.gov/17444623
Autor:
Srikanth, Venkatraman, Stéphane L, Bogen, Ashok, Arasappan, Frank, Bennett, Kevin, Chen, Edwin, Jao, Yi-Tsung, Liu, Raymond, Lovey, Siska, Hendrata, Yuhua, Huang, Weidong, Pan, Tejal, Parekh, Patrick, Pinto, Veljko, Popov, Russel, Pike, Sumei, Ruan, Bama, Santhanam, Bancha, Vibulbhan, Wanli, Wu, Weiying, Yang, Jianshe, Kong, Xiang, Liang, Jesse, Wong, Rong, Liu, Nancy, Butkiewicz, Robert, Chase, Andrea, Hart, Sony, Agrawal, Paul, Ingravallo, John, Pichardo, Rong, Kong, Bahige, Baroudy, Bruce, Malcolm, Zhuyan, Guo, Andrew, Prongay, Vincent, Madison, Lisa, Broske, Xiaoming, Cui, Kuo-Chi, Cheng, Yunsheng, Hsieh, Jean-Marc, Brisson, Danial, Prelusky, Walter, Korfmacher, Ronald, White, Susan, Bogdanowich-Knipp, Anastasia, Pavlovsky, Prudence, Bradley, Anil K, Saksena, Ashit, Ganguly, John, Piwinski, Viyyoor, Girijavallabhan, F George, Njoroge
Publikováno v:
Journal of medicinal chemistry. 49(20)
Hepatitis C virus (HCV) infection is the major cause of chronic liver disease, leading to cirrhosis and hepatocellular carcinoma, which affects more than 170 million people worldwide. Currently the only therapeutic regimens are subcutaneous interfero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d829742096e46d140179bde31ce0d830
https://pubmed.ncbi.nlm.nih.gov/17004721
https://pubmed.ncbi.nlm.nih.gov/17004721
Autor:
Naginbhai M. Patel, Eugene L. Moss, Roberta S. Hare, Frank Bennett, Patrick Pinto, Pike Russell E, Viyyoor M. Girijavallabhan, Anil K. Saksena, Yi-Tsung Liu, Raymond G. Lovey, Edwin Jao, David Loebenberg, Anthony Cacciapuoti, Amin A. Nomeir, Fred Menzel, Ashit K. Ganguly, Haiyan Wang
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(1)
As part of a detailed study, the syntheses, biological activities, and pharmacokinetic properties of hydroxylated analogues of the previously described broad spectrum antifungal agents, Sch 51048 (1), Sch 50001 (3), and Sch 50002 (4), are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c2c26e041c8d1f55cc640e41f9603e
https://pubmed.ncbi.nlm.nih.gov/16260134
https://pubmed.ncbi.nlm.nih.gov/16260134