Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Yi-Tao Yu"'
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1284 (2024)
Nonsense mutations are genetic mutations that create premature termination codons (PTCs), leading to truncated, defective proteins in diseases such as cystic fibrosis, neurofibromatosis type 1, Dravet syndrome, Hurler syndrome, Beta thalassemia, inhe
Externí odkaz:
https://doaj.org/article/dc0abfb2ff974808ba7bc0f4948b6dde
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The current COVID-19 pandemic is a massive source of global disruption, having led so far to two hundred and fifty million COVID-19 cases and almost five million deaths worldwide. It was recognized in the beginning that only an effective vaccine coul
Externí odkaz:
https://doaj.org/article/fb6a4596b2f94b4cbe9d7cc377d7a8b6
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Small nuclear RNAs (snRNAs) are critical components of the spliceosome that catalyze the splicing of pre-mRNA. snRNAs are each complexed with many proteins to form RNA-protein complexes, termed as small nuclear ribonucleoproteins (snRNPs), in the cel
Externí odkaz:
https://doaj.org/article/33c123b984a742129674da2e749645dd
Publikováno v:
Biology Open, Vol 6, Iss 9, Pp 1342-1354 (2017)
Many ribonucleoproteins (RNPs), which are comprised of noncoding RNA and associated proteins, are involved in essential cellular processes such as translation and pre-mRNA splicing. One class of RNP is the small Cajal body-specific RNP (scaRNP), whic
Externí odkaz:
https://doaj.org/article/42b851a613c3450d98e3c4b07a3c6f17
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 550 (2021)
Therapeutic oligonucleotides interact with a target RNA via Watson-Crick complementarity, affecting RNA-processing reactions such as mRNA degradation, pre-mRNA splicing, or mRNA translation. Since they were proposed decades ago, several have been app
Externí odkaz:
https://doaj.org/article/572256d2474b42de9af59d6f117e7179
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 6 (2018)
Pseudouridine is the most abundant internal RNA modification in stable noncoding RNAs (ncRNAs). It can be catalyzed by both RNA-dependent and RNA-independent mechanisms. Pseudouridylation impacts both the biochemical and biophysical properties of RNA
Externí odkaz:
https://doaj.org/article/ec9bb0126c9647eeb5280c90597df755
Publikováno v:
Biochemical Journal; Jan2024, Vol. 481 Issue 1, p1-16, 16p
Publikováno v:
Methods in Molecular Biology ISBN: 9781071631904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab01df71dd328c19eb2f69566be3242
https://doi.org/10.1007/978-1-0716-3191-1_14
https://doi.org/10.1007/978-1-0716-3191-1_14
Autor:
Hironori Adachi, Yi-Tao Yu
Publikováno v:
RNA. 26:1247-1256
We have previously shown that when the uridine of a stop codon (UAA, UAG, or UGA) is pseudouridylated, the ribosome reads through the modified stop codon. However, it is not clear as to whether or not the pseudouridine (Ψ)-mediated readthrough is de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95e96ed631ff698f133b304d9cad7cc0
https://doi.org/10.1261/rna.076042.120
https://doi.org/10.1261/rna.076042.120
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The current COVID-19 pandemic is a massive source of global disruption, having led so far to two hundred and fifty million COVID-19 cases and almost five million deaths worldwide. It was recognized in the beginning that only an effective vaccine coul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d0b6fbf66d2002e811d443f9c891b9
https://doi.org/10.3389/fcell.2021.789427
https://doi.org/10.3389/fcell.2021.789427